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Home › Medications › pantoprazole

pantoprazole

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of pantoprazole

25 trials tracked of pantoprazole: 12 in phase 3 or 4 and 3 with published results. The most-cited published study has 2443 citations.

25Trials tracked
12Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 6 Phase 3 6 Phase 2 4 Phase 1 3 Other / NA 6
  1. Phase 3 Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease Completed · 2,443 cited
  2. Phase 4 Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients Completed · 79 cited
  3. Phase 4 Stress Ulcer Prophylaxis in the Intensive Care Unit Completed · 33 cited
  4. Phase 4 Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS Completed
  5. Phase 4 Comparison of Pantoprazole and Ranitidine in Dyspepsia Completed
  6. Phase 4 A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation Completed
Show 19 more trials
  1. Phase 4 Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole Completed
  2. Phase 3 Aspirin in Young Psychotic Patients Completed
  3. Phase 3 Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD) Completed
  4. Phase 3 Pantoprazole on Insulin Secretion in Diabetes Completed
  5. Phase 3 Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD) Completed
  6. Phase 3 Study Evaluating Pantoprazole in Neonates and Preterm Infants With GERD Completed
  7. Phase 2 Incretin Effect and Use After Clinical Islet Transplantation Completed
  8. Phase 2 Histamine Glutamate Antagonism in Stroke Completed
  9. Phase 2 Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy Completed
  10. Phase 2 Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor Completed
  11. Phase 1 Drug-Drug Interaction of Cladribine and Pantoprazole in Multiple Sclerosis Subjects Completed
  12. Phase 1 Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Study Completed
  13. Phase 1 PK Study With Pantoprazole in Obese Children and Adolescents Completed
  14. N/A Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders Completed
  15. N/A Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea Completed
  16. N/A Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease Completed
  17. N/A Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS) Completed
  18. N/A Structured Non-operative Treatment of Knee Osteoarthritis Completed
  19. N/A Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD) Completed

Showing the 25 most-cited and recently-updated of 25 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Intravenous pantoprazole may trigger life-threatening Type I Kounis syndrome in patients with bronchial asthma
Cardiology Sys. Review
Intravenous pantoprazole may trigger life-threatening Type I Kounis syndrome in patients with bronchial asthma Pantoprazole May Trigger Rare Heart Complications in Asthma Patients
This case report and literature review describes a single instance of Type I Kounis syndrome following intravenous pantoprazole administrati…
A rare case shows how a common acid reflux medication may cause a severe heart reaction in a patient with a history of asthma.
Frontiers Sep 29, 2026
Omeprazole, rabeprazole, pantoprazole, and lansoprazole are associated with increased fracture risk in elderly patients
Drug Pipeline Meta-analysis
Omeprazole, rabeprazole, pantoprazole, and lansoprazole are associated with increased fracture risk in elderly patients Some acid reflux medications may increase fracture risk in seniors
This network meta-analysis of 257,445 patients indicates that omeprazole, rabeprazole, pantoprazole, and lansoprazole are associated with in…
New data suggests that certain acid reflux medications may increase the risk of bone fractures for adults over age 65.
Frontiers Sep 13, 2026
Pantoprazole Benefits COVID-19 ICU Patients Without Raising Mortality
Emergency Medicine RCT
Pantoprazole Benefits COVID-19 ICU Patients Without Raising Mortality Trial shows pantoprazole helps prevent gastrointestinal bleeding in COVID patients
In critically ill COVID-19 patients, pantoprazole reduced GI bleeding without increasing mortality, though infection itself worsened outcome…
A study of critically ill patients shows that the medication pantoprazole helps prevent serious stomach bleeding in those with COVID-19.
Sep 2, 2026
Pantoprazole exposure linked to insulin autoimmune syndrome in case report
Diabetes & Endocrinology Sys. Review
Pantoprazole exposure linked to insulin autoimmune syndrome in case report Stopping a stomach acid drug helped a patient with low blood sugar recover
This case report describes a patient with insulin autoimmune syndrome (IAS) temporally associated with pantoprazole exposure. Discontinuatio…
A patient with insulin autoimmune syndrome found relief when doctors stopped a common stomach acid medication, suggesting a possible link be…
Frontiers Jun 3, 2026