Proof of concept study uses preSCRIPT framework to annotate prescriptions in UK Biobank
preSCRIPT framework identifies genetic links to drug response in UK Biobank
This proof of concept study utilized the preSCRIPT framework to filter and annotate raw prescription data from the UK Biobank, which include…
A proof of concept study in the UK Biobank used preSCRIPT to find genetic links to how people respond to common medications like warfarin an…
Fetal paracetamol exposure linked to reduced ovarian and uterine volume in girls
Prenatal Paracetamol Linked to Smaller Ovaries and Uterus in Girls
This prospective, observational cohort study examined 3425 eligible participants, including 302 girls examined at follow-up. Fetal exposure …
Prenatal paracetamol exposure is linked to smaller ovaries and uterus in infant girls, raising new questions about long-term reproductive he…
Opioid prescribing in pregnancy increased in Catalonia from 2011 to 2020
Pregnant women getting more pain pills in Spain
This retrospective drug-utilization study of 41,398 pregnancies in Catalonia found that 2.41% involved opioid exposure, with prescribing inc…
A new study shows doctors in Spain are prescribing pain pills to pregnant women more often, but current rules might not be protecting babies…
Paracetamol or ibuprofen treatment outcomes in preterm infants with patent ductus arteriosus: a retrospective cohort analysis.
Tiny Hearts, Big Risk: New Clues to a Common Preemie Problem
This retrospective cohort study evaluated pharmacological treatment with intravenous paracetamol or ibuprofen in 60 preterm infants with pat…
For the tiniest premature babies, an open heart passage that doesn't close can be life-threatening, but early treatment helps most infants r…
CBD oil shows no surrogate evidence of drug interactions with opioids or benzodiazepines in advanced cancer patients
Study finds CBD oil did not increase side effects when taken with certain cancer medications
A randomized controlled trial in advanced cancer patients found no evidence from surrogate measures that CBD oil increased adverse effects o…
Advanced cancer patients taking CBD oil alongside pain and mental health drugs did not experience increased side effects or drug interaction…