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Psychiatry
Review of pooled psilocybin data suggests broadening blood pressure eligibility criteria for psychiatric trials
Psilocybin raises blood pressure briefly but stays safe for most patients
This pooled analysis review examined blood pressure and heart rate responses in 368 participants receiving 536 psilocybin sessions at Johns …
New data shows psilocybin raises blood pressure only briefly, suggesting doctors could safely treat more patients with mild high blood press…
medRxiv
Apr 30, 2026
Drug Pipeline
RCT
Three psilocybin doses (5–20 mg) in healthy volunteers showed dose-dependent functional connectivity changes.
Thinking Process:
This randomized controlled trial (RCT) enrolled 10 healthy volunteers who received three psilocybin doses between 5 and 20 mg in a randomize…
Lower psilocybin doses linked to decreased brain connectivity, while higher doses increased connections in healthy volunteers.
medRxiv
Apr 20, 2026