Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Medications › riluzole

riluzole

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of riluzole

17 trials tracked of riluzole: 5 in phase 3 or 4 and 3 with published results. The most-cited published study has 599 citations.

17Trials tracked
5Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 4 Phase 3 1 Phase 2 10 Phase 1 1 Other / NA 1
  1. Phase 4 Research Study for Major Depressive Disorder: Investigation of Glutamate Medications Completed · 599 cited
  2. Phase 3 Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS Completed · 136 cited
  3. Phase 4 Riluzole in Fragile X Syndrome Completed · 65 cited
  4. Phase 4 Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation Completed
  5. Phase 4 Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission Completed
  6. Phase 2 Neuroprotection With Riluzole Patients With Early Multiple Sclerosis Completed
Show 11 more trials
  1. Phase 2 Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery Completed
  2. Phase 2 Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders Completed
  3. Phase 2 Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder Completed
  4. Phase 2 Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS) Completed
  5. Phase 2 Riluzole in Mild Alzheimer's Disease Completed
  6. Phase 2 Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD) Completed
  7. Phase 2 A Double-Blind Placebo Controlled Trial of Riluzole in Bipolar Depression Completed
  8. Phase 2 Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) Completed
  9. Phase 2 Efficacy and Tolerability of Riluzole in Treatment Resistant Depression Completed
  10. Phase 1 A Pilot Study Of Riluzole In Patients With Post Traumatic Stress Disorder (PTSD) Completed
  11. N/A Riluzole in the Treatment of Bipolar Depression Completed

Showing the 17 most-cited and recently-updated of 17 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Masitinib 4.5 mg/kg/day associated with survival in ALS post-hoc analysis
Neurology RCT
Masitinib 4.5 mg/kg/day associated with survival in ALS post-hoc analysis This Drug Could Add Nearly Two Years to ALS Life
This post-hoc analysis of a randomized, double-blind, placebo-controlled trial in 130 ALS patients found that masitinib 4.5 mg/kg/day was as…
A new look at data suggests a specific drug might significantly extend life for some people with ALS.
medRxiv Apr 19, 2026