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Orthopedics & Sports Medicine
Meta-analysis
Potent bisphosphonate therapy reduces incident vertebral fractures by 71% after denosumab discontinuation
Potent bisphosphonates may lower fracture risk after denosumab treatment stops
This meta-analysis of 683 adults with osteoporosis or low bone mass found that potent bisphosphonate therapy significantly reduced incident …
Patients with osteoporosis may have a lower risk of spine fractures when switching to potent bisphosphonates after stopping denosumab.
NEJM
Sep 6, 2026
OB/GYN & Women's Health
Sys. Review
Peptide therapies may restore fertility after TRT suppression, but evidence is limited
New peptide therapies may help men with low testosterone and fertility
This narrative review examines peptide and neuroendocrine strategies for male hypogonadism, including kisspeptin-based therapies and GnRH-re…
Men using testosterone replacement therapy often face fertility issues. New peptide-based treatments could offer a way to protect reproducti…
Frontiers
Aug 14, 2026