Germline variants associated with chemotherapy-induced peripheral neuropathy show poor replication and limited clinical translation
Genetic Variations Linked to Chemotherapy Induced Nerve Damage
This systematic review of 72 studies assessed germline genetic variations related to vincristine, taxanes, platinum agents, and bortezomib. …
Specific genetic markers may be linked to nerve damage caused by chemotherapy, though these findings are not yet ready for use in clinical p…
Dose-dense adjuvant chemotherapy reduces invasive disease hazard by 38% in HER2-zero breast cancer
Dose-dense Chemotherapy Shows Benefit for Early Stage Breast Cancer
This exploratory analysis of a randomized controlled trial involving 1243 patients with node-positive early-stage HER2-negative breast cance…
A large study suggests that a dose-dense chemotherapy schedule may improve survival and outcomes for patients with HER2-negative breast canc…
Taxane-Based and Long-Course Chemotherapy Linked to Higher Breast Cancer-Related Lymphedema Risk
New Data Links Chemo Drugs to Arm Swelling in Breast Cancer
In a retrospective cohort of 201 breast cancer patients at Guangzhou Red Cross Hospital, taxane-based regimens, long-course chemotherapy, an…
Breast cancer patients on certain chemotherapy drugs face a higher risk of developing arm swelling after treatment ends.
Same-day desensitization linked to lower breakthrough reaction rate than rapid protocol in chemotherapy hypersensitivity
Can a same-day approach reduce allergic reactions during cancer treatment?
A retrospective cohort study of 120 patients with hypersensitivity reactions to platinum- or taxane-based chemotherapy compared same-day des…
A same-day desensitization approach reduced breakthrough allergic reactions to 15% compared to 24% for patients receiving rapid protocols du…