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Home › Medications › TCAs

TCAs

2 published articles · Updated continuously

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Patient Mode — summaries use plain language, avoiding clinical jargon.
Antidepressant use is associated with a 1.34 increased risk of ventricular arrhythmia and sudden cardiac death
Cardiology Meta-analysis
Antidepressant use is associated with a 1.34 increased risk of ventricular arrhythmia and sudden cardiac death Antidepressant use linked to higher risk of sudden cardiac death
This meta-analysis of 9,619,278 patients found that antidepressant use, including SSRIs and TCAs, is associated with a significantly increas…
A massive study of over 9 million people shows a link between antidepressant use and a higher risk of serious heart rhythm problems.
Sep 24, 2026
No significant association between BDNF genotypes and remission in major depressive disorder patients treated with antidepressants
Psychiatry Meta-analysis
No significant association between BDNF genotypes and remission in major depressive disorder patients treated with antidepressants Genetic markers do not predict antidepressant success in major depression
This meta-analysis review examined 599 Caucasian patients with a major depressive episode treated with SSRIs, SNRIs, or TCAs. The analysis f…
A large review found that specific genetic markers do not predict who will recover from depression when taking common antidepressant medicat…
Jun 1, 2026