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Home › Medications › thiamine

thiamine

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of thiamine

9 trials tracked of thiamine: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 284 citations.

9Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 7 Other / NA 1
  1. Phase 3 Vitamin C, Thiamine, and Steroids in Sepsis Completed · 284 cited
  2. Phase 2 Thiamine as a Renal Protective Agent in Septic Shock Completed
  3. Phase 2 Thiamine as an Adjunctive Therapy in Cardiac Surgery Completed
  4. Phase 2 Thiamine and Acute Decompensated Heart Failure: Pilot Study Completed
  5. Phase 2 High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Completed
  6. Phase 2 Thiamine as a Metabolic Resuscitator in Septic Shock Completed
Show 3 more trials
  1. Phase 2 The Effect of Thiamine vs. Placebo on VO2 in Critical Illness Completed
  2. Phase 2 Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis. Completed
  3. N/A Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness Completed

Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Micronutrient deficiencies and metabolic blocks impact pulmonary vasculopathy via the HIF axis and eNOS uncoupling
Cardiology Sys. Review
Micronutrient deficiencies and metabolic blocks impact pulmonary vasculopathy via the HIF axis and eNOS uncoupling Micronutrient Deficiencies Linked to Pulmonary Hypertension in Children
This systematic review of 115 articles synthesizes the impact of micronutrient deficiencies and metabolism disorders on pulmonary vasculopat…
New research suggests that common vitamin and mineral deficiencies may impact heart and lung health in children with pulmonary hypertension.
Frontiers Sep 24, 2026
High-dose thiamine use increased for Wernicke encephalopathy in Japan; functional impairment common at discharge
Neurology
High-dose thiamine use increased for Wernicke encephalopathy in Japan; functional impairment common at discharge Did more high-dose vitamin B1 help patients with alcohol-related brain damage?
A 13-year observational study of 7,856 hospitalized Wernicke encephalopathy patients in Japan found initial high-dose thiamine use increased…
Despite a surge in high-dose vitamin B1 use for alcohol-related brain damage, over half of patients still leave the hospital unable to care …
medRxiv Apr 5, 2026