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Home › Medications › trimethoprim-sulfamethoxazole

trimethoprim-sulfamethoxazole

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of trimethoprim-sulfamethoxazole

10 trials tracked of trimethoprim-sulfamethoxazole: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 21 citations.

10Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 2 Other / NA 3
  1. Phase 4 Antibiotic Prophylaxis for Transrectal Prostate Biopsy Completed · 21 cited
  2. Phase 4 Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations Completed · 15 cited
  3. Phase 4 Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management Completed
  4. Phase 3 Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) Completed
  5. Phase 3 Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA" Completed
  6. Phase 2 Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus Completed
Show 4 more trials
  1. Phase 2 Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia Completed
  2. N/A Study of New Antibiotic Regimen for the Treatment of Uncomplicated Cellulitis in Emergency Department Patients Completed
  3. N/A Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage Completed
  4. N/A Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
Hematology Meta-analysis
Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis Case report: Brain infection in autoimmune hepatitis patient
This case report describes the management of disseminated nocardiosis in a 55-year-old man with autoimmune hepatitis. The patient showed gra…
A man with autoimmune hepatitis developed a rare brain infection after immunosuppression. Doctors treated it successfully with targeted anti…
Frontiers Jul 17, 2026
Electronic health record study links prior antimicrobial resistance to bacteraemia in cancer patients
Infectious Disease
Electronic health record study links prior antimicrobial resistance to bacteraemia in cancer patients Prior Antibiotic Resistance Linked to Higher Bacteraemia Risk in Cancer Patients
This electronic health record study analyzed 2752 adults with cancer diagnostic codes in Oxfordshire, UK, between 2015 and 2025.
Past antibiotic resistance in cancer patients strongly predicts future bloodstream infections, with specific cancer types increasing odds of…
medRxiv Apr 26, 2026
Brief research report on toxicity-guided TMP-SMX dose reduction in disseminated nocardiosis
Drug Pipeline Guideline
Brief research report on toxicity-guided TMP-SMX dose reduction in disseminated nocardiosis Gold miner's rare infection treated with adjusted antibiotic dose
This brief research report describes a single case of disseminated nocardiosis with CNS involvement in a patient with pneumoconiosis.
A gold miner with a rare brain infection improved after doctors lowered his antibiotic dose due to severe side effects.
Frontiers Apr 24, 2026