Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
Case report: Brain infection in autoimmune hepatitis patient
This case report describes the management of disseminated nocardiosis in a 55-year-old man with autoimmune hepatitis. The patient showed gra…
A man with autoimmune hepatitis developed a rare brain infection after immunosuppression. Doctors treated it successfully with targeted anti…
Autoimmune hepatitis pathogenesis shifts from single molecule to immune-metabolic network analysis
New Research Maps Complex Networks in Autoimmune Hepatitis
This systematic review reframes autoimmune hepatitis (AIH) pathogenesis from a single-molecule perspective to a systematic regulatory networ…
Researchers are moving beyond single-molecule views to map complex immune and metabolic networks that drive autoimmune hepatitis.
Systematic review and meta-analysis of biopsy-guided versus clinically guided withdrawal in autoimmune hepatitis
Biopsy-guided withdrawal shows no benefit over clinical guidance for autoimmune hepatitis
This systematic review and meta-analysis evaluated relapse rates after treatment withdrawal in patients with autoimmune hepatitis.
A meta-analysis of 518 patients found that biopsy-guided withdrawal did not lower relapse rates compared to clinically guided withdrawal in …
Hepatic steatosis prevalence and impact in autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis
Fatty liver makes autoimmune hepatitis and PBC worse, but not PSC
This systematic review and meta-analysis of 19,898 patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing c…
A large review found fatty liver is common in autoimmune liver diseases and makes outcomes worse for some patients, but not others.
Research across Hepatitis
Related studies from across the Hepatitis family.
Eight-Week Sofosbuvir-Velpatasvir Matches Twelve-Week Course in Non-Cirrhotic Hepatitis C
Trial shows 8-week treatment works for Hepatitis C
In 880 treatment-naive adults with non-cirrhotic hepatitis C, 8 weeks of sofosbuvir-velpatasvir achieved SVR12 rates similar to the standard…
A shorter 8-week course of sofosbuvir and velpatasvir showed similar success rates to the standard 12-week treatment for Hepatitis C patient…
HBeAg positivity and high HBV DNA levels increase postpartum ALT elevation risk in chronic hepatitis B
Risk Factors for Liver Inflammation in Mothers with Hepatitis B
This meta-analysis of cohort studies identifies key risk factors for postpartum alanine aminotransferase (ALT) elevation in women with chron…
Specific factors like HBeAg positivity and high viral DNA levels can increase the risk of liver inflammation in women with chronic hepatitis…
HBsAg prevalence 7.0% in dialysis patients, with low HBV-DNA and suboptimal vaccination
Hepatitis B infection rates among patients on dialysis
This meta-analysis of 79 articles estimates hepatitis B burden in dialysis patients globally. Pooled HBsAg prevalence was 7.0% (95% CI 6.1-8…
New data shows that about 7% of patients on dialysis have Hepatitis B, highlighting the need for safer procedures and better vaccination rat…
Community health workers support infectious disease management and PrEP navigation in agricultural communities
Community health workers help farm workers manage infectious diseases
This mini-review examines the role of community health workers (CHWs) in managing infectious diseases among California agricultural workers.…
Community health workers can help farm workers manage serious infections like HIV, tuberculosis, and hepatitis through direct outreach and n…
Hepatic macrophage metabolic reprogramming and bidirectional signaling dictate the balance between liver injury and regeneration
New research identifies how liver cells communicate during chronic disease
This systematic review synthesizes the role of hepatic macrophages in metabolic dysfunction-associated steatotic liver disease, alcohol-asso…
New research reveals how specific immune cells in the liver switch between causing inflammation and repairing tissue damage.
Tonsillar metastasis in hepatocellular carcinoma patients may present as undifferentiated carcinoma with specific IHC markers
Lenvatinib and Chemoembolization Treatment Linked to Liver Cancer Metastasis
This case report and literature review describes a single patient with hepatocellular carcinoma and chronic hepatitis B presenting with a to…
A rare case of liver cancer spreading to the tonsils highlights the need for careful monitoring of head and neck symptoms in patients with l…
Direct-acting antiviral therapy and diverse viral infections require comprehensive epidemiological and diagnostic strategy review
Review Outlines Treatment and Prevention for Various Viral Infections
This systematic review covers the molecular biology, epidemiology, and treatment strategies for various viral infections including Hepatitis…
A comprehensive review outlines the biological traits, diagnosis methods, and treatment strategies for several common viral infections inclu…
Global HBsAg prevalence 3.2% in nurses, with 5.6% in Africa and 3.6% in LMICs
Nurses Face Higher Hepatitis B Risk in Poorer Countries
This meta-analysis estimates global hepatitis B surface antigen (HBsAg) prevalence among hospital-based nurses at 3.2% (95% CI 2.3-4.4), wit…
A global analysis finds 3.2% of hospital nurses carry hepatitis B, with rates four times higher in poorer countries.
Host non-coding RNAs orchestrate antiviral defense and are targeted by viral counter-defense strategies
Host molecules may help the body fight off common viruses
This systematic review examines how host non-coding RNAs, including miRNAs, lncRNAs, circRNAs, and vtRNAs, modulate antiviral responses agai…
Your body uses special molecules called non-coding RNAs to fight off viruses like flu, Zika, and COVID-19 by blocking their growth.
Incarceration acts as a structural determinant of health with higher rates of chronic and infectious diseases
Incarceration Linked to Higher Rates of Mental Illness and HIV
This narrative review of 167 articles examines the health status and care utilization of incarcerated adults in Canada. It finds significant…
People in correctional centers face higher rates of mental illness and chronic diseases compared to those living in the community.
Peg-interferon add-on to nucleoside analogues achieves HBsAg loss in 8.6% of patients
Adding peg-interferon to standard treatment helps some hepatitis B patients
This meta-analysis of 581 patients with chronic hepatitis B evaluates peg-interferon add-on to nucleoside analogue therapy. The analysis fou…
Adding peg-interferon to standard nucleoside therapy can help some patients with chronic hepatitis B achieve a key milestone in their treatm…
TZ84-based hepatitis A vaccine shows higher seroconversion rates and GMCs than HM175-based vaccine
TZ84 vaccine shows stronger long-term protection against hepatitis A
This meta-analysis of 3,282 children and adolescents found that the TZ84-based hepatitis A vaccine is associated with higher seroconversion …
One type of hepatitis A vaccine shows higher antibody levels and longer protection in children compared to another common vaccine type.