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Home › Medications › valacyclovir

valacyclovir

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of valacyclovir

19 trials tracked of valacyclovir: 7 in phase 3 or 4 and 1 with published results. The most-cited published study has 122 citations.

19Trials tracked
7Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 5 Phase 3 2 Phase 2 8 Phase 1 3 Other / NA 1
  1. Phase 4 Randomized Trial to Evaluate Suppressive Effect of High-Dose Valacyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2 Completed · 122 cited
  2. Phase 4 VALTREX(Valacyclovir) Once Daily for Viral Shedding In Subjects Newly Diagnosed With HSV-2 Completed
  3. Phase 4 Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV Completed
  4. Phase 4 Valacyclovir vs. Acyclovir as HSV-2 Suppressive Therapy: Effect on Plasma HIV-1 Levels Among HIV-1/HSV-2 Co-infected Persons Completed
  5. Phase 4 Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2 Completed
  6. Phase 3 Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir Completed
Show 13 more trials
  1. Phase 3 Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes Completed
  2. Phase 2 SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC Completed
  3. Phase 2 HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeeding Completed
  4. Phase 2 Anti-viral Therapy in Alzheimer's Disease Completed
  5. Phase 2 Systematic Evaluation of Antiviral Medication in Schizophrenia Completed
  6. Phase 2 Research Study of Bipolar Mood Symptoms and Cognitive Problems Completed
  7. Phase 2 Herpes Simplex Type 1 Suppression in Hepatitis C Completed
  8. Phase 2 ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation Completed
  9. Phase 2 Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma Completed
  10. Phase 1 Valacyclovir 1000 mg Tablet Under Fed Conditions Completed
  11. Phase 1 Evaluating Three Grams Daily Valacyclovir in Patients With Chronic Hepatitis C and HSV-2 Infection (Phase I) Completed
  12. Phase 1 Valacyclovir in Neonatal Herpes Simplex Virus Disease Completed
  13. N/A Effect of Valacyclovir in the Reduction of HSV-2 Recurrence and Shedding Completed

Showing the 19 most-cited and recently-updated of 19 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Aglatimagene plus valacyclovir improves disease-free survival in intermediate or high-risk prostate cancer patients
Drug Pipeline RCT
Aglatimagene plus valacyclovir improves disease-free survival in intermediate or high-risk prostate cancer patients New gene therapy helps prostate cancer patients stay disease-free longer after radiation treatment
This phase 3 randomised, double-blind, placebo-controlled trial enrolled 745 patients with intermediate or high-risk prostate cancer aged at…
A large trial found that a new gene therapy plus standard medicine helped patients with prostate cancer stay disease-free longer. This treat…
Jun 3, 2026
Valacyclovir No Better Than Placebo for Stromal Keratitis in Herpes Zoster Ophthalmicus
Infectious Disease RCT
Valacyclovir No Better Than Placebo for Stromal Keratitis in Herpes Zoster Ophthalmicus Oral antivirals do not prevent eye inflammation in shingles patients
This secondary analysis of a randomized trial in 527 patients with herpes zoster ophthalmicus found that oral valacyclovir 1 g daily did not…
A study of 527 people with shingles eye infections found oral antivirals did not stop inflammation. Close monitoring and low-potency steroid…
May 1, 2026