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Meta-analysis reveals caffeine benefits for female athletes in intermittent sports regarding agility and vertical jump performanceCaffeine helps female athletes in intermittent sports improve agility and vertical jump

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Key Takeaway
Caffeine improves agility and vertical jump in female athletes, but sprint performance is unaffected and cycle phase effects remain uncertain.

This meta-analysis evaluated the impact of caffeine on physical performance in female athletes participating in intermittent-type sports. The analysis pooled data from nine studies, with six contributing to the primary meta-analysis involving a total of 118 participants. The research aimed to determine if caffeine supplementation enhances specific athletic metrics in this population.

Results indicated significant improvements in agility and vertical jump height following caffeine consumption. The standardized mean difference for agility was substantial, while vertical jump showed a moderate positive effect. In contrast, sprint performance did not demonstrate any meaningful improvement with caffeine use. Additionally, subgroup analysis suggested that agility improvements were more pronounced during the follicular phase of the menstrual cycle.

Between-group analyses comparing different menstrual cycle phases revealed no statistically significant differences in caffeine effects. The certainty of effects observed during the luteal phase was lower than in other phases. Researchers noted limitations including a small number of studies with detailed menstrual cycle data and a lack of rigorous verification methods. Future well-designed studies are needed to robustly test whether caffeine responses truly differ across menstrual cycle phases.

Female athletes who play intermittent sports often wonder if caffeine helps them perform better. A new analysis looked at data from nine studies involving 118 women to answer this question. The research focused on how caffeine affects physical performance during exercise.

The results showed clear benefits for specific movements. Athletes taking caffeine demonstrated better agility and higher vertical jumps. The data suggested these improvements were consistent across different groups. However, the study did not find any boost in sprint performance.

The researchers also looked at how the menstrual cycle might change these results. They found no significant differences between the follicular and luteal phases. Yet, the evidence for effects during the luteal phase was less certain. The small number of studies with detailed cycle information limits what we can conclude.

Experts say we need better-designed studies to test if caffeine responses truly differ across cycle phases. Until then, the current data supports caffeine use for agility and jumping in this specific group of athletes.

What this means for you:
Caffeine improved agility and vertical jump in female athletes doing intermittent sports.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
IntroductionFemale athletes remain underrepresented in caffeine-based performance research, and inconsistent menstrual cycle classification further limits generalization of the current evidence. This systematic review and meta-analysis examined the effects of caffeine on physical performance in female athletes participating in intermittent sports and explored whether these effects differ between the menstrual cycle phases, within the constraints of the available literature.MethodsA systematic search was conducted (PubMed, Scopus, Web of Science) from January 2000 to September 2025. Randomized controlled trials evaluating caffeine effects on physical performance in female athletes participating in intermittent-type sports and reporting menstrual cycle phase were included. Random-effects meta-analyses using standardized mean differences were conducted and subgroup analysis by menstrual cycle phase were pre-specified. Study quality was assessed using the Physiotherapy Evidence Database scale and Risk-of-Bias tool.ResultsNine studies (n = 118) were included, and six (n = 82) contributed to the meta-analysis. Caffeine was associated with improvements in agility (SMD = −0.62, 95% CI [−0.98 to −0.26], I2 = 0%) and vertical jump (SMD = 0.37, 95% CI [0.05 to 0.69], I2 = 0%) but not sprint performance (SMD = 0.03, 95% CI [−0.36 to 0.41], I2 = 15.2%) with low heterogeneity across outcomes. Within-condition sub-group analyses suggested caffeine-related improvements in agility within follicular-phase samples (SMD = −0.84, 95% CI [−1.34 to −0.33]), whereas effects in the luteal phase were less certain. However, between-group analyses showed no differences in caffeine effects between menstrual cycle phases (Q [1] = 1.41, p = 0.24), and these findings were based on a limited and methodologically constrained evidence base.ConclusionCaffeine was associated with improvements in vertical jump and agility in females from intermittent sports. However, the small number of studies reporting menstrual cycle details, lack of appropriate experimental designs, and absence of rigorous menstrual cycle verification limit inference regarding phase-dependent effects. These findings highlight the need for well-designed studies to robustly test whether caffeine responses differ across menstrual cycle phases.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42025634451.
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