A new analysis of 16 studies involving 942 people with liver cirrhosis and sarcopenia (muscle loss) found that exercise programs can improve muscle strength and physical function. The meta-analysis looked at aerobic and resistance exercises and measured outcomes like walking distance, thigh circumference, and knee extensor strength.
Participants who exercised showed significant improvements in the 6-minute walk distance (an average increase of 54 meters), thigh circumference, knee extensor strength, thigh muscle thickness, and quality of life scores. Gait speed also improved. However, handgrip strength and liver disease severity scores (MELD) did not change significantly.
The study did not report any safety concerns or adverse events. The authors note that more research is needed to determine which type of exercise (aerobic vs. resistance) is most effective.
For people with cirrhosis and muscle loss, this analysis suggests that exercise may help improve muscle mass and physical performance. Talk to your doctor before starting any new exercise program.
