Narrative review explores immune monitoring for relapse prediction after AML stem cell transplant
Can better immune monitoring help predict relapse in leukemia patients after stem cell transplants?
This narrative review examines immune monitoring methodologies for predicting relapse in acute myeloid leukemia patients after allogeneic he…
New immune monitoring tools could spot leukemia relapse risks earlier than standard tests after stem cell transplants, helping doctors tailo…
Systematic review synthesizes immune and genetic factors in African SARS-CoV-2 populations
Why Africa saw milder COVID-19
This narrative synthesis reviews 40 studies from African settings regarding SARS-CoV-2 infection.
Africa saw milder COVID-19 because unique genes and immune defenses helped people fight the virus without getting severely sick.
Review of ISG15 pathway targeting for inflammatory and cardiovascular diseases
A Tiny Protein That Fuels Your Inflammation
This narrative review examines the potential of targeting the ISG15 pathway to treat inflammatory diseases, including skin, cardiovascular, …
Understanding this protein could lead to better medicines for skin, heart, and brain diseases.
Budesonide-glycopyrronium-formoterol fumarate dihydrate improved lung function and reduced severe exacerbations versus budesonide-formoterol in inadequately controlled asthma
New Asthma Drug Cuts Attacks Without Recent Crisis
This phase 3 randomised, double-blind, double-dummy, parallel-group trial evaluated budesonide-glycopyrronium-formoterol fumarate dihydrate …
A new asthma combo therapy improves breathing and lowers severe flare-up risk for patients who haven't had a recent emergency room visit.
Home-based e-based exercise protocol feasibility study for patients with multiple sclerosis and comorbidities
Working Out From Home Could Slow Multiple Sclerosis Progression
This protocol describes a home-based e-based physical exercise program for patients with multiple sclerosis (pwMS) with and without comorbid…
A new trial tests if twice-weekly online resistance exercise from home can improve walking ability and reduce disease activity in people wit…
Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
Your body has a built-in alarm system. It wakes up when you get a sore throat or a fever. But sometimes, this alarm gets stuck in the "on" position. That stuck alarm causes chronic pain and swelling. Scientists are finally learning how to turn it off
This systematic review examined molecular mechanisms involving natural compounds like oridonin and pristimerin, alongside synthetic inhibito…
A hidden protein key inside your cells triggers the stuck alarm that causes chronic pain and swelling, and scientists now know how to stop i…
Peri- and postmenopausal hormonal changes may exacerbate asthma, rhinitis, cough, allergies, hypersensitivity, anaphylaxis, and angioedema
Menopause Changes Allergy Rules for Women
This systematic review examines the association between declining and fluctuating estrogen and progesterone levels and various allergic and …
Menopause can worsen allergies like hay fever and asthma because dropping estrogen levels make your immune system more reactive to triggers.
AQST-109 sublingual film shows faster time-to-peak concentration than epinephrine autoinjectors in healthy adults
The Allergy Shot That Goes Under Your Tongue Instead
A phase 3 RCT in healthy adults compared AQST-109 sublingual film to intramuscular epinephrine.
A dissolving film under the tongue delivers epinephrine faster than an EpiPen, offering a needle-free option for severe allergy emergencies.
Occupational toxic particle exposure linked to increased pulmonary sarcoidosis risk in meta-analysis
The Dusts and Fumes Linked to a Strange Lung Disease
This systematic review and meta-analysis evaluated 13 studies published between 2000 and 2025 to assess occupational exposures as risk facto…
A review of 13 studies found that specific workplace dusts and chemicals are linked to sarcoidosis, a mysterious lung disease that leaves ti…
Systematic review assesses liquid biopsy technologies for early detection of drug resistance and therapeutic response monitoring in people
A Simple Blood Test May Catch When Your Cancer Treatment Stops Working
This systematic review evaluated liquid biopsy technologies, including ctDNA, CTCs, and EVs, for monitoring tumor genomics and customizing t…
A simple blood test can detect when cancer evolves to resist treatment weeks before standard scans show any change.
Strategies to screen and reduce adverse events in patients with asthma using systemic corticosteroids
Asthma Patients Are Still Getting Too Many Steroids — Here Is Why That Matters
This systematic review examined real-world practice strategies aimed at identifying and screening patients at risk of adverse events associa…
Asthma patients face serious, preventable harm from overused systemic steroids, yet safer biologics aren't reaching enough people who need t…
Mini-review examines natural product compounds in rodent depression models
Nature's Keys Unlock Depression's Fire
This mini-review evaluated compounds from natural products in rodent models of depression.
Natural compounds may fight depression by targeting brain inflammation through the P2X7 receptor, offering new hope for treatments beyond tr…