Meta-analysis finds systemic lupus erythematosus elevates coronary artery disease risk
People with lupus face higher heart disease risk but genetics show no direct link
This meta-analysis of 2,517,781 individuals from European and East Asian populations found that systemic lupus erythematosus is associated w…
A massive analysis of millions of people found those with lupus have a much higher risk of heart disease, though genetics do not prove a dir…
Residual angina occurs in 42.2% of patients after anatomic complete revascularization for chronic coronary disease
Residual angina affects over 40% of patients after complete heart artery treatment
This randomized controlled trial evaluated symptomatic patients with chronic coronary disease undergoing invasive management. At six months,…
More than 40% of patients still have chest pain six months after complete heart artery treatment, impacting daily life and medication needs.
M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation
Heart Valve Repair Improves Symptoms in Heart Failure Patients
This RCT subgroup analysis found that mitral transcatheter edge-to-edge repair (M-TEER) reduced the risk of cardiovascular death or heart fa…
A study found that mitral valve repair with MitraClip improved symptoms and reduced hospitalizations in heart failure patients with mitral r…
Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months
Simplified care plan shows no overall benefit for heart failure patients
This multicenter randomized clinical trial enrolled 982 patients with acute heart failure. The study evaluated a simplified transitional car…
A new trial found that a simplified discharge plan did not improve medication adherence or symptoms for most heart failure patients, though …
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.
Olezarsen showed no significant difference versus placebo in noncalcified plaque volume change over 12 months in adults with moderate hypertriglyceridemia
New trial shows olezarsen did not reduce plaque volume compared to placebo in adults with high triglycerides
This randomized, placebo-controlled trial enrolled 468 adults with moderate hypertriglyceridemia and followed them for 12 months. The primar…
A study of 468 adults found that taking olezarsen did not lower plaque volume better than taking a dummy pill. Safety was also similar betwe…
Network meta-analysis compares DOACs and VKAs for intracranial hemorrhage risk
Dabigatran may be safest for brain bleeding risk
This network meta-analysis of 127,267 patients with venous thromboembolism or atrial fibrillation found that all DOACs had lower risk of int…
All blood thinners beat warfarin for brain bleed risk, but dabigatran may be the safest choice.
Narrative review outlines QT monitoring protocols for cancer patients
Cancer patients need better heart monitoring during treatment
This narrative review from MD Anderson Cancer Center discusses QT monitoring protocols and cardiac electrophysiology principles for cancer p…
A new review shows why cancer patients need careful heart monitoring to prevent dangerous rhythm problems.
Review of bedside ligation for patent ductus arteriosus in an extremely low birth weight infant
A single case shows bedside ligation works for a tiny newborn with a heart hole
This review and synthesis examines a single case report of bedside ligation for patent ductus arteriosus in an extremely low birth weight in…
A single case report suggests bedside ligation can close a heart hole and help a tiny newborn breathe easier without major surgery.
Systematic review and meta-analysis of drug-coated balloons versus drug-eluting stents in coronary artery disease
Meta-analysis links drug balloons to higher heart risks
This systematic review and meta-analysis evaluated drug-coated balloons (DCB) versus drug-eluting stents (DES) in 8,123 patients with corona…
A review of 8,123 patients found drug-coated balloons for heart arteries may raise risks of repeat procedures and cardiac death compared to …
Meta-analysis finds cerebral embolic protection does not reduce stroke in TAVR patients
New review shows brain protection devices did not lower stroke risk for heart valve patients
This systematic review and meta-analysis of 11,696 patients undergoing transcatheter aortic valve replacement found that cerebral embolic pr…
A large study of over eleven thousand patients found that using special filters during heart valve surgery did not lower the chance of havin…
Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence
Cochrane review finds little benefit for drugs treating Friedreich ataxia
This Cochrane systematic review evaluated pharmacological treatments for people with genetically-confirmed Friedreich ataxia. The analysis i…
A major review of eight studies found that most drugs for Friedreich ataxia likely make little difference to key symptoms compared to placeb…