Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Deferral of PCI non-inferior to routine PCI before TAVI in coronary artery disease patients
Study finds delaying heart artery procedure before valve replacement is as safe as doing it first
A randomised controlled trial of 466 patients undergoing TAVI with coronary artery disease in 12 Dutch hospitals found deferral of PCI was n…
Delaying heart artery procedures before valve replacement is just as safe as doing them first, with similar rates of death, heart attack, st…
Image-based deep learning models show high accuracy for aortic dissection segmentation and diagnosis compared to clinicians
AI Reads Your Scan Better Than Doctors
This systematic review and meta-analysis pooled data from 48 studies evaluating image-based deep learning models against clinicians for aort…
Smart computer programs now spot life-threatening aortic tears with accuracy that matches top human doctors, catching dangerous signs humans…
Sacubitril/valsartan shows greater LVMI regression than some antihypertensives in hypertension with remodeling
New Drug Shrinks Heart Muscle Better Than Old Options
A network meta-analysis of 851 patients with essential hypertension and cardiovascular remodeling found sacubitril/valsartan achieved greate…
A new analysis shows one specific medicine shrinks thickened heart muscle better than older blood pressure treatments, offering hope for rev…
External validation of three DVT prediction models in 1,270 acute stroke patients
Three DVT prediction models showed varying accuracy in a single-center stroke study
This single-center spatial validation cohort study assessed three deep vein thrombosis (DVT) prediction models in 1,270 patients with acute …
The Lu Qiufang model outperformed others with 82.1% accuracy in predicting deep vein thrombosis among 1,270 acute stroke patients at a Shenz…
Meta-analysis shows altered muscle morphology and metabolism in heart failure patients versus healthy controls
Why Your Muscles Change in Heart Failure
This systematic review and meta-analysis of 35 studies compared cross-sectional muscle morphology and metabolism in patients with heart fail…
Heart failure doesn't just weaken the heart; it silently rewrites the blueprint of your leg muscles to make them less efficient.
HIIT improves cardiorespiratory fitness and waist circumference in sedentary adults versus no exercise
HIIT exercise improves fitness and waist size in sedentary adults, review finds
A Cochrane systematic review of 2,075 healthy, sedentary adults found that high-intensity interval training (HIIT) likely increases VO2max a…
High-intensity interval training likely boosts fitness and shrinks waist size for sedentary adults, though more research is needed to confir…
Serum biomarkers stratify disease severity in acute myocarditis cohorts
New Blood Test Predicts Heart Attack Risk in Inflammation
This prospective cohort study analyzed 103 patients across two independent settings to evaluate serum analyses and multimodal data integrati…
A new blood test predicts heart attack risk by spotting inflammation signals from repair workers in the heart muscle.
Serial echocardiography in severe aortic regurgitation shows LVESD and FS changes predict risk
Does waiting for a specific heart measurement number actually keep you safe?
A retrospective analysis of 140 patients with severe aortic regurgitation undergoing serial echocardiographic follow-up found that small inc…
Waiting for a specific heart measurement to justify surgery may miss warning signs, as every millimeter of heart widening raises risk by 5% …
Probiotics with high-fiber diet linked to lower blood pressure in hypertensive patients
Your Gut Bacteria May Be a Hidden Lever for Blood Pressure
A retrospective cohort study of 322 hypertensive patients found that a 3-month regimen of probiotics combined with a high-fiber diet was ass…
Combining probiotic supplements with a high-fiber diet changed the gut microbiome in ways that measurably lowered blood pressure and improve…
GWAS meta-analysis identifies 89 loci for mitral valve prolapse and genetic links to hypertrophic cardiomyopathy
New DNA Clues Link Heart Valve to Dangerous Rhythms
This meta-analysis of genome-wide association studies (GWAS) evaluated genetic factors in over 2.2 million individuals, including 21,517 cas…
Imagine your heart has a tiny door that sometimes swings too wide.
GMPI software packages show varied reference values for left ventricular function in low-risk CAD patients
Your Heart's "Normal" Range May Depend on Your Sex and Age
A retrospective cohort of 142 consecutive patients with low-risk coronary artery disease found significant differences in left ventricular f…
What's considered normal heart function on a common imaging test varies by sex and age, with new benchmarks showing significant differences …