Fluoxetine Linked to Small but Significant Blood Pressure Rise
Fluoxetine linked to small rise in blood pressure
A meta-analysis of 538 participants found fluoxetine associated with modest increases in systolic and diastolic blood pressure versus placeb…
A review of trials finds fluoxetine may raise blood pressure slightly, a finding that warrants caution for people taking the antidepressant.
Meta-analysis of CMR biomarkers in diabetes shows elevated ECV and reduced perfusion
Heart scans show warning signs in patients with diabetes
This systematic review and meta-analysis synthesized cardiac magnetic resonance biomarker data in patients with diabetes. It found significa…
A large review of heart scans found clear warning signs in patients with diabetes, including higher fluid buildup and reduced blood flow to …
Review of immunomodulatory strategies for myocardial infarction notes major translational gaps and undefined heart-immune axis
New ideas for heart attack treatment face big scientific hurdles
This review examines immunomodulatory strategies targeting the CCR2/CCL2 axis, regulatory T cells, and macrophage polarization compared to c…
Experts review new immune-targeting strategies for heart attacks but note major gaps in understanding how the heart and immune system intera…
Systematic review and meta-analysis links traffic noise to hypertension risk
Long-term traffic noise exposure linked to higher hypertension risk in adults
This systematic review and meta-analysis synthesized evidence on long-term traffic noise exposure and hypertension incidence in adults. The …
A massive analysis of over 1.3 million adults found that living near busy roads increases the risk of developing high blood pressure.
LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.
Narrative review proposes phenotype-driven framework for managing myelofibrosis splenomegaly
New combo strategies shrink spleens better than older treatments for myelofibrosis
This narrative review addresses the management of splenomegaly in patients with myelofibrosis. The authors synthesize evidence regarding eme…
Emerging combination strategies like pelabresib plus ruxolitinib or navitoclax plus ruxolitinib show superior spleen shrinkage for myelofibr…
FDA Approves Argatroban in Sodium Chloride for Thrombosis in HIT and PCI
FDA approves new blood thinner for patients with rare clotting disorder.
The FDA approved Argatroban in Sodium Chloride injection for prophylaxis or treatment of thrombosis in adult patients with heparin-induced t…
The FDA approved Argatroban in Sodium Chloride injection to prevent or treat blood clots in adults with heparin-induced thrombocytopenia (HI…
Edoxaban trough concentration and PT predict major bleeding in very old AF patients
Blood thinner levels linked to bleeding in very old patients
This post hoc analysis of the ELDERCARE-AF RCT included 427 very old Japanese patients with atrial fibrillation and high bleeding risk. High…
Higher edoxaban levels in the blood may increase bleeding risk in patients 80 and older with atrial fibrillation.
Scoping review finds exercise preserves ventricular-arterial coupling in male adults
Physical activity preserves heart efficiency in men with various risk factors
This scoping review synthesizes evidence on exercise and physical activity regarding ventricular-arterial coupling in male adults. The autho…
A review of 2,229 men found that exercise and aerobic training help maintain heart efficiency and reduce arterial load.
Baseline BMI does not significantly alter exercise capacity or lipid improvements in cardiac rehabilitation patients
Obesity does not limit heart rehab exercise gains
This systematic review and meta-analysis evaluated eighteen studies involving patients undergoing cardiac rehabilitation after cardiac event…
For people in cardiac rehab, starting weight did not change how much their exercise capacity improved, a new review finds.
Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
Metabolic syndrome raises atrial fibrillation risk by 1.5 to 2 times
This narrative review examines the association between metabolic syndrome and atrial fibrillation. The authors synthesize evidence suggestin…
Metabolic syndrome increases the risk of developing atrial fibrillation by 1.5 to 2 times, a finding that could help doctors target preventi…