Sugammadex improves diaphragmatic excursion and reduces pulmonary complications in morbidly obese patients
Sugammadex Helps Obese Patients Breathe Easier
A randomized double-blind controlled trial in 104 morbidly obese patients compared sugammadex (2 mg/kg) with neostigmine+atropine.
This new research shows that a specific reversal drug helps morbidly obese patients breathe better and avoid lung issues after surgery.
Circulating spexin levels are significantly lower in patients with type 2 diabetes mellitus compared to controls
The Hormone That Goes Missing When Diabetes Arrives
This systematic review and meta-analysis evaluated circulating spexin levels in 1,122 patients with type 2 diabetes mellitus and 681 control…
A little-known hormone called spexin shows up in much smaller amounts in people with type 2 diabetes, hinting at a possible link scientists …
Risk factors for recurrence in patients undergoing percutaneous endoscopic lumbar discectomy for lumbar disc herniation
Back Surgery Worked — So Why Did the Disc Come Back?
This systematic review and meta-analysis evaluated 14,454 patients undergoing percutaneous endoscopic lumbar discectomy (PELD) for lumbar di…
A large analysis of nearly 15,000 patients identifies who is most likely to need repeat back surgery — and what lifestyle factors make recur…
Cultural dietary patterns linked to lower obesity risk in global meta-analysis
Your Food Habits Are Shaping Your Weight Risk
A meta-analysis of 48 studies across 68 countries found that traditional dietary patterns were associated with a 23% lower obesity risk and …
Sticking to traditional diets lowers obesity risk by 23% compared to Westernized eating, while moving away from home culture raises it.
Meta-analysis links BMI to breast cancer subtype risk with menopausal status differences
Does Weight Change Breast Cancer Risk? It Depends on When
A systematic review and meta-analysis of 2,103,181 pre- and post-menopausal women found BMI associations with breast cancer subtype risk var…
Extra weight raises breast cancer risk after menopause, but before menopause it's linked to more aggressive tumor types, a review of over 2 …
PRP infusion improves pregnancy rates in recurrent implantation failure but may increase preterm births
Platelet Plasma Boosts Pregnancy in Repeat Failures
A meta-analysis in women with recurrent implantation failure found that intrauterine autologous platelet-rich plasma (PRP) infusion signific…
Platelet-rich plasma triples pregnancy rates for women with recurrent implantation failure, but it also raises the risk of preterm birth.
Meta-analysis identifies risk factors for diabetic kidney disease in Asian patients with type 2 diabetes
High Blood Pressure Is A Major Kidney Killer For Asian Diabetics
A meta-analysis of 24 studies including 12,047 Asian patients with type 2 diabetes found that SBP, hypertension, HbA1c, WHR, FBG, UA, Cr, ag…
High blood pressure is a top kidney killer for Asian diabetics, making blood pressure control just as critical as managing sugar levels to p…
GnRHa treatment in familial hCG syndrome associated with concurrent beta-hCG elevation in blood and CSF
When a Pregnancy Hormone Shows Up in a Child — and It Is Not Cancer
This case report describes an 8-year-old girl with central precocious puberty treated with a gonadotropin-releasing hormone agonist (GnRHa).
An inherited condition can mimic a brain tumor in children by raising pregnancy hormones, leading to unnecessary surgery and chemotherapy be…
Systematic review of gouty arthritis models highlights limitations in reproducing human disease complexity
New Gout Models Could Finally Fix Chronic Pain
This systematic review evaluated various gouty arthritis models, including exogenous monosodium urate and hyperuricemia models, as well as c…
Better lab models mean scientists can finally target the root causes of long-term gout pain instead of just hiding the symptoms.
Burosumab improved clinical and biochemical outcomes in patients with tumor-induced osteomalacia
Can a new drug help patients with tumor-induced bone loss before surgery?
This hybrid study, combining a clinical survey with a systematic review, evaluated burosumab in patients with tumor-induced osteomalacia.
A new drug helps patients with tumor-induced bone loss improve health and blood chemistry while waiting for surgery or if surgery isn't poss…
Protein nutritional support in critically ill adults shows heterogeneous mortality benefits and potential harm from very high early doses
Why ICU Patients Need More Protein, But Not Too Much
This narrative review evaluates protein supplementation strategies in critically ill adults, including those with sepsis or severe burns.
Doctors caring for patients in the ICU know protein matters for recovery, but a new review shows the right dose depends on the illness, the …
Endocrine-disrupting chemicals may contribute to obesity and adiposity in humans
Hidden Chemicals Linked to Weight Gain
This narrative mini-review examines human studies regarding endocrine-disrupting chemicals (EDCs) and their potential role in obesity.
Invisible chemicals in your environment can trick your cells into storing fat, making weight loss harder than diet and exercise alone can fi…