Narrative review examines GDF-15 potential in diabetic osteoporosis with limited clinical application evidence
New Target Found for Bone Loss in Diabetes
This narrative review examines the role of GDF-15 in patients with diabetic osteoporosis and diabetes mellitus.
A new protein called GDF-15 links diabetes to weak bones, offering a specific target for future treatments to stop dangerous fractures in pa…
Bioinformatics study identifies shared immune genes and potential drugs for PCOS and T2DM
Could existing drugs treat shared genes in PCOS and type 2 diabetes?
A preclinical bioinformatics and experimental validation study analyzed GEO datasets from patients with PCOS and T2DM, identifying 239 commo…
A study identified 239 genes linked to both PCOS and type 2 diabetes, with 40 existing drugs like maraviroc potentially targeting them for n…
Cross-Sectional Analysis of Protective Foot Sensation and Complications in 387 Type 2 Diabetes Patients
Smoking and kidney disease link to worse diabetes nerve damage in feet
This retrospective cross-sectional study evaluated 387 patients with Type 2 diabetes and Diabetic Peripheral Neuropathy at University Hospit…
Smoking and severe kidney disease greatly increase the risk of losing protective feeling in the feet, leading to dangerous complications for…
Prospective observational cohort evaluates Tardivo Algorithm risk stratification and outcomes in diabetic foot patients
What does a new risk tool mean for people with diabetic foot problems?
This prospective observational cohort study included 42 adult patients with diabetic foot in a vascular surgery outpatient setting.
A new risk tool tracked healing in 42 diabetic foot patients, showing 94% kept their limbs and wounds healed in about five months during rou…
Atherogenic index of plasma shows non-linear association with mortality in diabetic AKI patients
Research finds blood marker linked to death in diabetic kidney injury
A retrospective cohort study of 1046 diabetic patients with acute kidney injury found that the atherogenic index of plasma (AIP) had a non-l…
Higher levels of a specific blood marker are linked to a greater risk of death in people with diabetes and acute kidney injury.
Expert meeting report reviews pharmacological strategies for acquired hypothalamic obesity
Could new drugs help patients with hypothalamic obesity finally control their hunger and lose weight?
An expert meeting report from Frankfurt am Main, Germany, discussed pharmacological strategies including dextroamphetamine, glucagon-like pe…
New drugs targeting hunger pathways show promise for patients with hypothalamic obesity, offering hope where diets and exercise have failed …
Early pregnancy FT4 levels show non-linear association with gestational diabetes mellitus risk in 40,682 women
Low-Normal Thyroid Hormones Raise Diabetes Risk
This retrospective cohort study of 40,682 pregnant women evaluated early pregnancy thyroid hormones (FT4, TSH) against normal function range…
Even thyroid numbers that look "normal" on a lab report might actually signal a higher chance of developing gestational diabetes.
Nomogram using baseline SUA and CD4+ count predicts hyperuricemia risk in people living with HIV
What raises uric acid in HIV? New tool spots risk before symptoms start
This retrospective single-center study in Hangzhou, China derived and internally validated a nomogram predicting time to hyperuricemia (HUA)…
A new tool predicts high uric acid risk in HIV patients using just two factors: starting uric acid levels and CD4+ T-cell counts.
Multidisciplinary management in T2DM patients yielded a 29.24% remission rate in a single-arm observational study
Nearly 1 in 3 Reversed Type 2 Diabetes in Special Clinic
This single-arm observational study evaluated 171 patients with Type 2 Diabetes Mellitus receiving remission-oriented treatment at a special…
A special diabetes clinic helped nearly one in three patients reach remission, meaning they no longer needed diabetes pills after six months…
Case series suggests pain relief and quality of life improvement with multimodal therapy in fibromyalgia
Small case series suggests combined therapies may help three patients with fibromyalgia
This case series evaluated 3 patients with refractory fibromyalgia using low frequency Pulsed Electromagnetic Field therapy, medical ozone i…
Three patients with tough fibromyalgia cases found lasting pain relief and better quality of life after a 30-day mix of PEMF therapy, ozone,…
Total IgG Concentration Linked to Anemia in Hemodialysis Patients
Is low immunity linked to anemia in dialysis patients, or just age?
This cross-sectional study included 351 participants, comprising 179 dialysis patients and 172 healthy controls.
Dialysis patients with weaker overall immune defenses are more likely to have anemia, while protection from chickenpox offers little clue ab…
Retrospective study derives age- and sex-specific reference intervals for triglyceride-glucose index
Why do we need better standards for this common blood measurement?
This retrospective study derived and validated age- and sex-specific reference intervals (2.5th–97.5th percentiles) for the triglyceride-glu…
A common blood test for insulin resistance lacks standard reference ranges, leaving doctors without clear guidelines for interpreting result…