Sugar acts as a pivotal ecological factor influencing metabolism, biofilm formation, and interspecies interactions in dental caries
New Strategies Help Prevent Dental Caries Through Ecological Management
This narrative review explores the role of dietary sugars and various prevention strategies like fluoride application and probiotics in mana…
Sugar plays a major role in how bacteria build plaque on teeth, but new strategies like probiotics and fluoride may help balance the oral mi…
Computational strategies facilitate identification of conserved antigens and potential therapeutics in parasitic diseases
Computational Tools Help Identify New Treatments for Parasitic Diseases
This systematic review evaluates the role of computational methods including genomics, proteomics, and artificial intelligence in parasitolo…
New computer-based methods are helping scientists find new ways to treat parasitic diseases by identifying drug targets and vaccine markers.
Gram-negative organisms and multidrug resistance are prevalent in dental unit waterlines
Bacteria in dental water lines show resistance to common antibiotics
This scoping review of 18 studies identifies a prevalence of Gram-negative organisms, such as Pseudomonas spp., in dental unit waterlines. T…
Research shows that bacteria found in dental unit waterlines can resist several common types of antibiotics used to treat infections.
No risk score outperformed WHO IMCI criteria for predicting pediatric pneumonia mortality
Risk Scores Do Not Outperform Standard Care for Pneumonia
This secondary analysis of a randomized controlled trial evaluated five risk scores in 1010 children with pneumonia across five African coun…
New analysis shows standard clinical tools are just as effective as complex risk scores for predicting pneumonia outcomes in children.
Mycobacteriophages show promise for drug-resistant mycobacterial infections in One Health approach
Phages Show Promise for Drug-Resistant Infections
This systematic review examines mycobacteriophages as tools for drug-resistant mycobacterial infections. The authors find them promising for…
Viruses that attack bacteria could help diagnose and treat hard-to-cure infections in people, animals, and the environment.
FDA Approves Zyvox (linezolid) for Gram-Positive Infections Including MRSA
FDA approves new antibiotic Zyvox for serious bacterial infections.
FDA approved Zyvox (linezolid) for nosocomial pneumonia, community-acquired pneumonia, complicated and uncomplicated skin infections, and va…
The FDA has approved Zyvox (linezolid) to treat serious infections caused by Gram-positive bacteria, including pneumonia and skin infections…
FDA Approves Linezolid Injection for Gram-Positive Infections Including Pneumonia and Skin Infections
FDA approves new antibiotic injection for serious bacterial infections
The FDA approved linezolid injection for nosocomial pneumonia, community-acquired pneumonia, complicated skin infections, and vancomycin-res…
The FDA approved linezolid injection for treating serious infections like pneumonia and skin infections caused by certain bacteria, includin…
Intrawound vancomycin powder reduces postoperative infection risk (OR 0.59) in high-risk fracture fixation cases
Vancomycin Powder May Reduce Infections After High Risk Fractures
This meta-analysis of 3185 patients found that intrawound vancomycin powder significantly reduced postoperative infection rates (OR 0.59; 95…
A review of data suggests that using vancomycin powder in wounds may lower infection rates for patients with serious bone fractures.
Plant essential oils demonstrate significant inhibitory effects against key subgingival plaque microbial complexes in periodontitis
Plant essential oils show promise against gum disease bacteria
This systematic review synthesizes the antibacterial activity of plant essential oils, including carvacrol and thymol, against subgingival p…
Certain plant oils may fight the specific bacteria that cause periodontitis while also helping to block harmful biofilm from forming in the …
Fungal biotransformation platform may generate new anti-infective molecules to combat antimicrobial resistance
Fungal Biotransformation May Help Combat Antimicrobial Resistance
This narrative review discusses fungal biotransformation as a discovery platform for generating structurally refined metabolites with anti-i…
New research explores how fungal systems can transform chemicals into new molecules to help fight stubborn bacterial and fungal infections.
Regenerative endodontic procedures may lead to unusual root morphology in immature teeth
Regenerative procedures can lead to unusual tooth root growth
This case report with literature review describes 2 immature teeth with pulp necrosis secondary to dens evaginatus treated with regenerative…
A new look at dental treatments shows that while some procedures save teeth, they can sometimes cause unexpected changes in how roots grow.
Risk-adapted HLA delisting and imlifidase enable deceased-donor kidney transplantation for highly sensitized candidates
New guide helps transplant kidneys for hardest-to-match patients
This expert consensus provides a practical guideline for managing highly sensitized adult patients on the waitlist for deceased-donor kidney…
A new expert guide shows how to safely transplant kidneys into highly sensitized patients who have few options left.