APOE ε4 status does not significantly impact neurocognitive performance in adults with HIV infection
APOE Status Does Not Impact Cognitive Health in HIV Patients
This meta-analysis of 2610 adults with HIV found no significant difference in cognitive performance or diagnosis of neurocognitive impairmen…
A large review of data suggests that the APOE e4 gene does not change cognitive performance or impairment for adults living with HIV.
NF-kB pathway serves as a unifying hub for molecular and clinical phenotypes in post-acute infection syndrome
New research identifies shared biological markers for chronic fatigue conditions
This systematic literature review synthesized 142 studies to identify biomarkers and pathomechanisms for post-acute infection syndrome (PAIS…
Researchers identified a common biological pathway linked to post-acute infection syndrome, which may help explain the underlying causes of …
Triple antibiotic paste and calcium hydroxide show comparable success in necrotic immature teeth
Triple Antibiotic Paste Shows Success for Necrotic Immature Teeth
This meta-analysis evaluated the clinical success rates of triple antibiotic paste, double antibiotic paste, and calcium hydroxide for regen…
New research shows triple antibiotic paste and calcium hydroxide are both highly effective at saving immature teeth with infections.
Three-variable stratification tool identifies risk of invasive pulmonary aspergillosis in SFTS patients
New Tool Helps Identify Fungal Infection Risk in SFTS Patients
This meta-analysis and systematic review evaluates a three-variable diagnostic stratification tool for identifying invasive pulmonary asperg…
A new diagnostic tool helps doctors identify patients with severe fever and thrombocytopenia who are at higher risk for a specific fungal in…
0.01% atropine reduces axial length by 0.04 mm/year in children with myopia
Low Dose Atropine Shows Mixed Results for Children with Myopia
This meta-analysis of randomized controlled trials evaluates the efficacy of 0.01% atropine for managing myopia in children. The analysis fo…
A low dose of atropine may slow eye growth in children with myopia, though its effects are less consistent than stronger doses.
Salmonella prevalence in bovine deep tissue lymph nodes reaches 10.8% across 33 studies
Salmonella found in 10.8% of beef lymph nodes
This meta-analysis of 33 studies evaluates Salmonella prevalence and concentration in bovine deep tissue lymph nodes (DTLNs). The analysis f…
A meta-analysis of 33 studies finds Salmonella in about 1 in 10 deep tissue lymph nodes from cattle, with higher rates in warm weather and f…
Doxycycline provides higher odds of microbiological cure compared to azithromycin in cis-men with chlamydia
Doxycycline Shows Higher Cure Rates for Chlamydia in Men
This systematic review and meta-analysis of 1172 patients found that doxycycline (OR = 2.525, 95% CI: 1.329-4.796, p = 0.005) provides a hig…
A review of clinical data suggests doxycycline may be more effective than azithromycin for treating chlamydia infections in men.
Antibiotic resistance mutations drive H. pylori treatment failure across Asia-Pacific region
Antibiotic resistance in H. pylori rising across Asia
This meta-analysis of H. pylori infections in the Asia-Pacific region finds that clarithromycin resistance (19-34%) is driven by A2142G/A214…
H. pylori bacteria in Asia are increasingly resistant to common antibiotics, driven by specific mutations.
Many healthcare students lack knowledge that antibiotics do not speed recovery from colds and flu
Healthcare students often lack clear knowledge on antibiotics and viruses
This meta-analysis of 131 studies from 43 countries found that while 88.7% of healthcare students correctly knew antibiotics treat bacterial…
Many healthcare students are unsure if antibiotics can treat common colds or flu, which may lead to improper use of these important medicine…
Pooled Salmonella prevalence in Ethiopia is 6.7% with significant regional and source variations
Tracking Salmonella Bacteria and Drug Resistance Across Different Areas of Ethiopia
This meta-analysis of 43 datasets from 39 articles identifies a pooled Salmonella prevalence of 6.7% (95% CI: 5.3-8.1%) across human, animal…
New data shows how common Salmonella is in people, animals, and the environment while tracking how well it resists common medicines.
Novel biomarkers and machine learning algorithms facilitate earlier identification and diagnosis of sepsis
New Diagnostic Tools May Help Identify Sepsis More Quickly
This narrative review explores the evolution of sepsis diagnostic strategies from traditional clinical scoring systems to advanced markers l…
Newer biomarkers and machine learning tools are evolving beyond traditional scoring systems to help doctors identify sepsis earlier in patie…
Non-invasive biomarkers offer potential alternatives to invasive kidney biopsy for monitoring renal allograft pathology
New non-invasive tests may replace invasive kidney transplant biopsies
This mini review explores non-invasive biomarkers, including donor-derived cell-free DNA and extracellular vesicles, as tools for monitoring…
Doctors are looking for ways to monitor kidney transplants using blood and urine tests instead of painful, invasive needle biopsies.