Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis.
Luteolin shows potential benefits in early studies for neurodegenerative diseases
This review of preclinical studies and preliminary clinical observations suggests luteolin may reduce neuroinflammation and improve function…
Luteolin may help slow brain decline in Alzheimer's and Parkinson's by calming inflammation and boosting antioxidant defenses in early studi…
Spatial coupling of enlarged perivascular spaces and white matter lesions observed across Alzheimer's disease continuum stages.
Do enlarged brain spaces link to early Alzheimer's changes?
This observational cohort study analyzed participants from the Alzheimer's Disease Neuroimaging Initiative dataset categorized by cognitive …
People with early Alzheimer's memory issues have swollen brain drainage tubes right next to damaged areas, suggesting these changes happen b…
Active bilingualism associated with better neuropsychological function and biomarker profiles in Alzheimer's disease compared to passive bilingualism.
Do speaking two languages help protect your brain from Alzheimer's disease?
This cohort study examined Spanish-Catalan bilinguals with biomarker-confirmed Alzheimer's disease. Active bilinguals outperformed passive b…
People with Alzheimer's who actively speak two languages show better brain function and lower disease markers than those who do not.
Pipeline Embolization Device in Small Vessels (<2 mm) Shows 52% 1-Year Occlusion, 16.9% Ischemic Events
Study of Pipeline Device in Small Vessels Shows Mixed Results
A retrospective multicenter cohort of 71 patients with intracranial aneurysms in parent vessels <2 mm found a 1-year complete occlusion rate…
A Pipeline device in tiny brain vessels closed 80% of aneurysms long-term but caused strokes in 17% of patients, with longer devices raising…
Early nutrition and rehabilitation protocol associated with better outcomes in severe subarachnoid hemorrhage
Can early feeding and rehab help severe brain bleed survivors recover better?
A retrospective cohort study of 102 patients with severe SAH (Hunt–Hess grade III–V) found that combined early enteral nutrition (within 48 …
Starting feeding and rehab within three days helped severe brain bleed survivors recover better, spend less time in the hospital, and avoid …
Earlier endovascular therapy within 24 hours associated with smaller infarct and better outcomes in LVO stroke.
Does waiting longer for stroke treatment cause more brain damage and worse recovery?
This prospective cohort study evaluated 216 patients with anterior circulation large-vessel occlusion stroke treated with endovascular thera…
Waiting longer for stroke treatment causes more dead brain tissue and leaves fewer patients able to live independently after 90 days.
ESKD Patients Had Higher ED Hospitalization, Mortality During COVID-19 Pandemic in South Korea
Did the pandemic make emergency visits and deaths worse for adults with end-stage kidney disease?
A retrospective cohort study of 159,456 ED visits by adult ESKD patients in South Korea found increased hospitalization (aOR 1.054) and mort…
Adults with end-stage kidney disease faced higher risks of hospitalization and death during the pandemic, while emergency visits increased f…
Higher systemic immune-inflammation index associated with increased mortality after ischemic stroke
Higher inflammation marker linked to increased death risk after ischemic stroke
A retrospective cohort study of 1,156 ischemic stroke patients found that each standard deviation increase in the systemic immune-inflammati…
Higher inflammation levels after an ischemic stroke are linked to a 17% greater risk of death for every standard increase in the blood test …
Tirofiban plus aspirin associated with lower early neurological deterioration in branch atheromatous disease
Early tirofiban plus aspirin linked to fewer early neurological declines in branch atheromatous disease patients
A retrospective single-center cohort study in patients with acute branch atheromatous disease found early tirofiban plus aspirin was associa…
Early tirofiban plus aspirin reduced early neurological decline from 55.1% to 10.1% in branch atheromatous disease patients compared to stan…
9.4T MRI shows similar FCD detection to 3T in small epilepsy cohort, reveals one quantitative feature
Can a stronger MRI scanner find hidden seizure causes that a standard scan misses?
A small cohort study of 21 patients with drug-resistant focal epilepsy found 9.4T MRI did not identify new epileptogenic lesions in 3T-negat…
A powerful 9.4T MRI scanner spotted hidden seizure causes in two patients that standard scans missed, but found no new issues in others.
Normative MRI modelling identifies critical brain volume deviations associated with disability in multiple sclerosis.
Do brain scans show more warning signs of disability in multiple sclerosis than in healthy people?
This observational cohort study applied a normative model trained on 62,444 healthy MRI datasets to scans from 362 people with multiple scle…
Brain scans reveal that people with multiple sclerosis have more critical volume deviations than healthy individuals, directly linked to hig…
CSF alpha-synuclein seed amplification assay shows high intra-individual consistency in Parkinson's disease
Does a single brain scan truly predict Parkinson's disease years later?
An observational review of the PPMI cohort (n=1238) found serial CSF alpha-synuclein seed amplification assay (aSyn-SAA) results were highly…
A single brain scan predicting Parkinson's disease stays accurate for most patients, but results for healthy people without the disease can …