Modified CIMT with trunk restraint improves function in chronic stroke patients
Six weeks of tailored therapy improved function and quality of life for chronic stroke patients
A single-blinded RCT in 34 chronic stroke patients found that adding patient-tailored modified constraint-induced movement therapy (mCIMT) w…
Thirty-four people with long-term stroke saw better movement and balance after six weeks of a specific therapy mix compared to standard care…
Exoskeleton-assisted robotic therapy improves upper limb motor scores versus conventional rehabilitation in poststroke inpatients
Robotic Therapy Helps Stroke Patients Regain Arm Function Faster
This multicenter, single-blind randomized controlled trial enrolled 94 inpatients with moderate-to-severe upper limb impairment within three…
A trial of 94 stroke patients found robotic arm therapy led to significantly better motor recovery than standard rehabilitation within five …
Anodal tDCS combined with therapy enhanced verb naming in chronic post-stroke aphasia
Stimulation plus therapy improves word finding in chronic stroke aphasia
This double-blind, sham-controlled crossover study investigated anodal tDCS over the left inferior frontal gyrus combined with verb naming t…
A small study found that combining brain stimulation with speech therapy helped people with chronic stroke aphasia name verbs better, with b…
Post-hoc ATTEND trial analysis shows stroke severity and caregiver factors predict 6-month outcomes in India
Stroke recovery in India depends heavily on age and caregiver support
This post-hoc analysis of a multicentre, prospective, randomised, open blinded endpoint trial evaluated 1,250 participants with acute stroke…
A look at 1,250 stroke patients in India shows that older age and certain caregivers predict worse long-term outcomes.
Systematic review and meta-analysis of dietary restriction in Alzheimer's mouse models
Dietary restrictions show mixed results in Alzheimer's mouse models
This systematic review and meta-analysis of 23 studies examined five dietary restriction regimens in Alzheimer's disease mouse models.
A meta-analysis of 23 studies found fasting-mimicking diets had the largest effects, while intermittent fasting improved memory but worsened…
Systematic review and meta-analysis finds abdominal acupuncture may improve poststroke constipation
Acupuncture plus standard care helps poststroke constipation, but evidence remains uncertain
This systematic review and meta-analysis of 943 patients evaluated abdominal acupuncture combined with conventional therapy for poststroke c…
A meta-analysis suggests acupuncture combined with standard care improves bowel movements for stroke survivors, though study limits make res…
Frexalimab study validates PROMIS-Fatigue-MS-8a and MSIS-29v2 in relapsing multiple sclerosis patients
New tools reliably measure fatigue in multiple sclerosis
This Phase 2 trial assessed psychometric validation of PROMIS-Fatigue-MS-8a and MSIS-29v2 in adults with relapsing multiple sclerosis.
Two questionnaires accurately track fatigue in relapsing MS, offering a new way to measure treatment benefits in trials.
Systematic Review and Meta-Analysis: Non-Invasive Brain Stimulation for Visual Perception After Stroke
New brain stimulation helps stroke patients see better than before
This systematic review and meta-analysis examined non-invasive brain stimulation (NIBS) for visual perception after stroke.
A new review shows brain stimulation helps stroke patients see better, offering hope for those struggling with vision loss after a stroke.
Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
Mindfulness and Melatonin May Help Sleep in Multiple Sclerosis
This systematic review and meta-analysis evaluated non-pharmacologic and pharmacologic interventions for sleep in people with multiple scler…
A review of ten studies suggests mindfulness, melatonin, and other therapies may improve sleep for people with multiple sclerosis, though mo…
Meta-analysis shows reduced stress-induced autonomic responses in people with multiple sclerosis compared to controls
People with MS show reduced autonomic responses to stress compared to controls
This meta-analysis reviews fourteen studies examining autonomic responses to emotional or stress-related stimuli in people with multiple scl…
A meta-analysis of fourteen studies found that people with multiple sclerosis have lower stress-induced autonomic responses than healthy con…
Meta-analysis shows MRI volumetric differences in Parkinson's disease with mild cognitive impairment versus cognitively normal patients
New scan signs reveal early brain changes in Parkinson's dementia risk
This systematic review and meta-analysis evaluates gray matter volume alterations across six subcortical regions in patients with Parkinson'…
A new scan pattern shows specific brain shrinkage in Parkinson's patients who are starting to forget things, helping doctors catch dementia …
Systematic review identifies ferroptosis as a key mechanism in acquired sensorineural hearing loss
New way to stop cell death may protect hearing
This systematic review examines the role of ferroptosis in various forms of sensorineural hearing loss, including noise-induced and age-rela…
Scientists found that stopping a specific type of cell death could help prevent hearing loss caused by noise, age, or certain drugs.