AhR signaling exhibits dual neurotoxic or neuroprotective effects depending on specific ligand types
Gut Health and AhR Signaling Linked to Alzheimer's and Parkinson's
This systematic review examines the role of Aryl hydrocarbon receptor (AhR) signaling in Alzheimer's and Parkinson's disease. The authors co…
New research highlights how different gut-related signals can either harm or protect the brain in conditions like Alzheimer's and Parkinson'…
Transcutaneous auricular vagus nerve stimulation mechanisms and parameter optimization reviewed
New research explores how ear nerve stimulation helps neurological conditions
This systematic review synthesizes neuroimaging, autonomic, and molecular pathways underlying transcutaneous auricular vagus nerve stimulati…
Scientists are mapping out how stimulating the vagus nerve through the ear could offer new ways to treat various neurological and systemic d…
Multidimensional biomarker panels suggest a complex pathological basis for post-stroke depression in the DRN-mPFC circuit
New framework identifies biological markers for depression after a stroke
This narrative review synthesizes evidence regarding the biological drivers of post-stroke depression (PSD). It proposes a framework where P…
A new research framework identifies how different biological factors, like inflammation and chemicals in the brain, combine to cause depress…
Transitional care interventions reduce rehospitalization and improve quality of life in adult stroke survivors
Transitional care helps stroke survivors stay out of the hospital
This systematic review and meta-analysis of 3,520 adult stroke survivors found that transitional care interventions reduced overall rehospit…
Specialized transitional care can cut hospital readmissions for stroke survivors by nearly half within three months of leaving the hospital.
Acupuncture-related therapies significantly reduce overall, physical, and mental fatigue in chronic fatigue syndrome patients
Acupuncture may help reduce physical and mental fatigue in CFS
This meta-analysis of 8 RCTs involving 715 patients found that acupuncture-related therapies were superior to control interventions for redu…
New data suggests acupuncture-related therapies can lower overall, physical, and mental fatigue for people living with chronic fatigue syndr…
Intravenous thrombolysis does not improve excellent functional recovery in patients with minor acute ischemic stroke
Thrombolytic drugs may not improve recovery for minor strokes
This meta-analysis of randomized controlled trials evaluated intravenous thrombolysis compared to nonthrombolytic standard of care for minor…
New data suggests that using clot-busting drugs might not provide extra benefits for patients with minor, non-disabling strokes.
cGAS-STING signaling pathway activation drives inflammation, fibrosis, and functional decline in various kidney diseases
Immune pathway linked to kidney disease progression
This systematic review explores the role of the cGAS-STING signaling pathway in renal pathologies. The authors conclude that this pathway is…
A newly mapped immune pathway may drive kidney damage, opening doors for future treatments.
FDA Approves Morphine Sulfate Oral Solution for Acute and Chronic Pain
FDA approves new morphine liquid for severe pain in adults and children.
The FDA approved Morphine Sulfate Oral Solution (2 mg/mL and 4 mg/mL) for acute and chronic pain in adults and pediatric patients 2 years an…
The FDA approved Morphine Sulfate Oral Solution for severe pain that requires an opioid and hasn't been helped by other treatments. It comes…
FDA Approves Xtampza ER (oxycodone) for Severe Persistent Pain
FDA approves new long acting painkiller Xtampza ER for severe pain
FDA approved Xtampza ER, an extended-release oxycodone, for severe persistent pain requiring an opioid when alternative options are inadequa…
The FDA approved Xtampza ER, a long acting oxycodone capsule, for severe pain that cannot be managed with other treatments. It is taken ever…
FDA Approves OxyContin (oxycodone) for Severe Pain in Adults and Pediatric Patients
FDA approves new opioid painkiller OxyContin for severe pain.
FDA approved OxyContin (extended-release oxycodone) for management of severe and persistent pain requiring an opioid analgesic in adults and…
The FDA approved OxyContin, a strong opioid painkiller, for severe pain that cannot be managed with other treatments. It is for adults and c…
FDA Approves Morphine Sulfate Tablets for Acute and Chronic Pain
FDA approves morphine sulfate tablets for acute and chronic pain.
The FDA approved Morphine Sulfate Tablets for acute pain in adults and pediatric patients weighing at least 50 kg, and for chronic pain in a…
The FDA approved morphine sulfate tablets for acute pain in adults and children over 50 kg, and chronic pain in adults, when other treatment…
Neuroprotective anesthesia targets protocol aims to reduce silent brain infarction and perioperative neurocognitive disorders
New trial plans to protect brain health during heart surgery
This randomized controlled trial protocol describes a study of 912 patients undergoing elective cardiac surgery with cardiopulmonary bypass.…
A new large-scale study aims to see if specific anesthesia targets can prevent brain damage and cognitive issues for patients undergoing hea…