Meta-analysis links speech features to severity in Parkinsons, cerebral palsy, and ALS
Speech patterns may help track disease severity in Parkinsons and other conditions
This meta-analysis synthesizes evidence from 890 speakers across 5 languages to evaluate a training-free method for assessing speech degrada…
A new computer method tracks Parkinson's and other disease severity by measuring how specific speech sounds change without needing special t…
Telemedicine network associated with lower 90-day mortality and care needs in rural acute neurological disorders
Could a 24/7 telemedicine network help rural hospitals save lives after a stroke or brain injury?
This prospective cohort study in rural northeast Germany evaluated a digitally enabled hub-and-spoke telemedicine network for adults with ac…
Rural hospitals using a 24/7 telemedicine network saw lower death or nursing home rates for stroke patients compared to similar facilities w…
Neutrophil SIRL-1/IL-8 Ratio as a Diagnostic Biomarker for Inflammatory Bowel Disease
New Blood Ratio Could Spot IBD Faster
This single-center cohort study measured neutrophil SIRL-1 and serum IL-8 in 90 IBD patients and healthy volunteers.
A new blood ratio measuring two immune signals could help doctors diagnose Crohn's and Ulcerative Colitis faster and more accurately.
SHAP-based model predicts pneumonia after aneurysmal subarachnoid hemorrhage embolization
Doctors Can Now Predict a Dangerous Complication After Brain Bleeds
This retrospective cohort study of 290 patients with aneurysmal subarachnoid hemorrhage evaluated a prediction model for stroke-associated p…
Doctors can now predict who will develop pneumonia after a brain bleed, allowing faster action to save lives.
Gut microbiota and inflammatory biomarkers associate with 1-year neurological recovery in cerebral hypoxia-ischemia cohort
Gut Bacteria Could Predict Brain Recovery After Oxygen Loss
This single-center cohort study analyzed 772 patients with cerebral hypoxia-ischemia to identify biomarkers associated with 1-year neurologi…
Gut bacteria levels and blood markers can predict how well a patient will recover after a stroke or cardiac arrest.
Observational cohort finds high cardiac involvement and variable treatment patterns in hATTR patients
Heart Treatment Often Misses Nerve Damage in This Group
This single-center retrospective cohort study of 54 patients with hereditary transthyretin amyloidosis (hATTR) found 94.4% had cardiac invol…
Heart patients with a common African American gene variant often get nerve damage missed, leaving tingling hands untreated while doctors foc…
Plasma proteomics profiling reveals differential protein expression in Alzheimer's and frontotemporal dementia
Can a simple blood test tell Alzheimer's from frontotemporal dementia?
An observational cohort study of 101 Asian individuals with known pTau217 status used plasma proteomics profiling to identify 1,168 proteins…
A simple blood test could distinguish Alzheimer's from frontotemporal dementia by spotting unique protein patterns linked to brain inflammat…
Etalanetug reduces CSF tau biomarkers in dominantly inherited Alzheimer's disease in phase 1b/2 study
Can a new drug slow Alzheimer's toxic tau protein in the brain?
This open-label phase 1b/2 study in 8 participants with mild-to-moderate cognitive impairment due to dominantly inherited Alzheimer's diseas…
An early study shows an experimental drug lowers two key tau proteins in spinal fluid for people with a rare inherited form of Alzheimer's.
Protocol for observational study of digital cognitive assessments in post-COVID-19 condition
New Tool Spots “Brain Fog” After COVID in Just 15 Minutes
This is a protocol for a single-center, cross-sectional observational study in the Luxembourgish Predi-COVID cohort.
A new digital tool spots lingering brain fog after COVID in just 15 minutes, offering a faster alternative to long clinic visits for million…
Observational analysis of a multi-channel blood biomarker framework for Alzheimer's amyloid detection
Can a simple blood test spot Alzheimer's brain changes as well as a brain scan?
This observational analysis from the ADNI cohort evaluates a Virtual Spectral Decomposition (VSD) framework using plasma biomarkers to detec…
A new blood test combining four markers spots Alzheimer's brain changes with 90% accuracy, outperforming single-marker tests without needing…
Non-randomized trial of Zoom system for LVO stroke reperfusion exceeds performance goals
Can a new stroke device clear deadly clots faster and more often?
This is a prospective, multicenter, non-randomized investigational device exemption trial in 260 adults with anterior circulation LVO stroke…
A new stroke device cleared deadly clots in 83% of patients within three tries, restoring blood flow in just 19 minutes.
Non-randomized trial of neuromodulation prehabilitation for brain tumor language networks
Small study tests brain stimulation and language training before brain tumor surgery
This is a non-randomized controlled trial in 26 patients with operable brain tumors.
Brain stimulation and language training before surgery reduced overlap between stimulation targets and language areas in patients with opera…