Age and sex drive distinct immune microenvironment and evasion mechanisms in cancer patients
Age and sex influence how cancer drugs work in patients
This systematic review synthesizes how age and sex influence the anti-tumor immune microenvironment and immune evasion mechanisms. The autho…
New research shows that a patient's age and sex change how their immune system fights cancer and responds to treatment.
High CAR-HEMATOTOX scores correlate with increased ICAHT odds and worse survival in CAR T-cell therapy
New Risk Score Identifies Complications in CAR T-cell Therapy
This meta-analysis evaluates the CAR-HEMATOTOX score as a risk-stratification tool for patients receiving CAR T-cell therapy for hematologic…
A new scoring tool helps identify patients at higher risk for severe complications and infections during CAR T-cell therapy for blood cancer…
Machine learning models predict cancer symptoms with AUC values ranging from 0.76 to 0.86
Machine Learning Models Predict Common Symptoms in Cancer Patients
This meta-analysis of 34 studies evaluated the predictive accuracy of machine learning models for common cancer symptoms. The analysis found…
New data shows machine learning models can predict pain, fatigue, and other common symptoms in patients living with cancer.
Viral hepatitis infections pose significantly higher risk for liver cancer than smoking-related lung cancer
Comparing the risks of liver cancer from hepatitis versus lung cancer from smoking
This meta-analysis of 86,097,714 participants analyzed the relative risks of liver cancer from various exposures compared to lung cancer fro…
New data shows that certain hepatitis viruses pose a much higher risk for liver cancer than smoking does for lung cancer.
Olaparib maintenance therapy significantly improves progression-free survival in advanced ovarian cancer patients
Olaparib Maintenance Therapy Delays Progression in Advanced Ovarian Cancer
This meta-analysis of randomized trials evaluates olaparib maintenance therapy for advanced ovarian cancer following platinum-based chemothe…
Olaparib maintenance therapy significantly delays disease progression in advanced ovarian cancer, especially for patients with specific gene…
Higher preoperative neutrophil-to-lymphocyte ratio predicts poorer survival in oral squamous cell carcinoma patients
High white blood cell ratios predict survival in oral cancer
This meta-analysis of 30 studies indicates that a higher preoperative neutrophil-to-lymphocyte ratio (NLR) is significantly associated with …
A high ratio of neutrophils to lymphocytes before surgery can help doctors predict survival outcomes for patients with oral squamous cell ca…
Integrating immunohistochemistry with next-generation sequencing improves diagnosis and risk stratification for myxoid glioneuronal tumor
New genetic testing helps identify rare brain tumor types
This case report and literature review examines the molecular profiling of myxoid glioneuronal tumor (MGNT). The authors conclude that combi…
Combining tissue samples with advanced genetic sequencing helps doctors identify rare brain tumors and find potential targets for future tre…
Locally advanced thyroid cancer is associated with increased rates of difficult airway and tracheal invasion
New data reveals risks and surgical outcomes for thyroid cancer
This meta-analysis of 6142 patients with thyroid cancer, including those with locally advanced and complex disease, identifies significant r…
New data highlights the risks of airway issues and nerve damage for patients facing complex or advanced thyroid cancer cases.
Digital CBTi reduces insomnia severity scores more than telephone or group delivery methods
Digital therapy shows promise for cancer patients with insomnia
This systematic review and network meta-analysis of 2040 adult cancer patients found that digital CBTi (dCBTi) significantly reduced ISI sco…
Digital cognitive behavioral therapy can help cancer patients fall asleep faster and stay asleep longer compared to standard care.
Robotic-assisted endoscopic submucosal dissection achieves 98.2% en-bloc and 96.8% R0 resection rates in GI neoplasms
Robotic surgery shows high success for removing gastrointestinal tumors
This Bayesian single-arm meta-analysis of 183 lesions indicates that robotic-assisted endoscopic submucosal dissection (R-ESD) achieves high…
Robotic-assisted surgery shows high success rates for removing gastrointestinal tumors, though more large-scale studies are needed to confir…
UFT combined with radiotherapy achieves a 38% pooled objective response rate in advanced pancreatic cancer
UFT Combined with Radiotherapy Shows Promise for Pancreatic Cancer
This meta-analysis of observational studies evaluates UFT combined with radiotherapy for patients with advanced pancreatic cancer. The analy…
A review of observational data suggests that combining UFT with radiotherapy may improve response rates for patients with advanced pancreati…
Lu-PSMA-617 combined with ADT and ARPI reduced radiographic progression risk by 28%
New Treatment Options for Men with Advanced Prostate Cancer
This Phase 3 randomized controlled trial of 1144 patients with PSMA-positive metastatic androgen pathway modulator-naive/sensitive prostate …
A large study shows that adding a specific radioactive treatment to standard hormone therapy can help slow cancer growth.