Systematic review and meta-analysis finds higher intracranial aneurysm prevalence in pituitary adenoma patients
Pituitary tumor patients have a higher rate of brain aneurysms than the general population
This systematic review and meta-analysis of 74 and 5264 patients found a 4% pooled prevalence of intracranial aneurysms in pituitary adenoma…
People with pituitary adenomas are more likely to have brain aneurysms than average. This review analyzed thousands of patients to find the …
Yoga reduces depression in breast cancer patients across multiple treatment groups
Yoga reduces depression in breast cancer patients, meta-analysis finds
A meta-analysis of 21 studies shows yoga significantly lowers depression in breast cancer patients, with strong effect sizes across surgery,…
A meta-analysis of 21 studies found yoga significantly reduced depression levels in breast cancer patients, suggesting a useful complementar…
Narrative review explores macrophage reprogramming for liver fibrosis and MASH
Scientists explore new ways to reprogram liver cells to heal damaged tissue and stop scarring
This narrative review summarizes macrophage reprogramming strategies for liver fibrosis and MASH. Approaches include gene modulation, pharma…
A recent review looks at fresh methods to change how liver immune cells behave. These changes could help heal liver scarring and improve hea…
Systematic Review Links Neural Circuit Disturbances to Glioma Symptoms and Survival
Brain tumor growth linked to disrupted neural circuits
This systematic review synthesizes evidence that circuit-level disturbances in the neural microenvironment correspond with glioma-related ep…
A new review shows that glioma disrupts brain circuits, linking seizures, mood changes, and survival. Could rewiring the brain help treat tu…
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins
A rare kidney tumor in a young adult was removed with clear margins and no spread
This case review describes a 23-year-old female who underwent right radical nephrectomy for a rare epithelial-type Wilms tumor. Histopatholo…
A 23-year-old woman had a rare kidney tumor removed. The surgery showed clear edges and no spread. This case highlights the need for awarene…
Ibrutinib plus chemo without ASCT shows survival benefit in mantle cell lymphoma
Adding stem cell transplant to ibrutinib treatment offered no extra benefit for lymphoma patients
In younger patients with mantle cell lymphoma, adding ASCT to an ibrutinib regimen did not improve outcomes but increased toxicity. Ibrutini…
Adding stem cell transplant to ibrutinib did not improve survival for younger lymphoma patients but increased side effects.
Systematic review finds activity pacing may improve cancer-related fatigue during chemotherapy
Activity pacing helps reduce tiredness for some cancer patients during chemotherapy treatment
This systematic review and meta-analysis of 5 studies (617 participants) found that activity pacing-related interventions had a small, non-s…
A review of six hundred seventeen patients found activity pacing might help reduce tiredness, especially during chemotherapy. However, overa…
Age and comorbidity do not raise severe complication risk after minimally invasive esophagectomy
Older esophageal cancer patients face no higher risk of severe complications with minimally invasive surgery
A secondary analysis of an RCT found that older age and higher comorbidity were not linked to more severe complications after minimally inva…
Analysis of 245 patients shows age and health conditions do not increase severe complication rates after minimally invasive esophagectomy.
Review of gynecologic malignancies highlights dormant tumor cells as a therapeutic target
Doctors find dormant cancer cells could help stop gynecologic cancer from coming back after treatment
This narrative review examines ovarian, cervical, endometrial, and uterine sarcoma cancers. The authors synthesize evidence regarding dorman…
A review shows that sleeping cancer cells might cause tumors to return. Targeting these hidden cells could help prevent recurrence in ovaria…
Closing rectal wall defects after full-thickness excision reduces bleeding and re-admission rates compared to leaving defects open in patients with rectal neoplasms
Closing the rectal wall defect lowers bleeding and re-admission rates after surgery
A systematic review and meta-analysis of six studies found that closing rectal wall defects after full-thickness excision significantly lowe…
A review of six studies found that closing the rectal wall defect after surgery significantly reduced bleeding and re-admission rates compar…
Angiogenic ccRCC tumors show higher pancreatic metastasis rate in phase II trial
Pancreatic Metastases Predict Better Sunitinib Response in Kidney Cancer
This phase II RCT of 305 treatment-naive ccRCC patients found that angiogenic tumors had a higher rate of pancreatic metastases (21% vs. 6.9…
Kidney tumors with certain genetic patterns are more likely to spread to the pancreas. Patients with these pancreatic metastases respond bet…
Morning immune checkpoint inhibitor infusions associated with improved survival in metastatic non-small-cell lung cancer
Giving cancer immunotherapy in the morning may help patients live longer
This emulated pragmatic randomized controlled trial in Veterans Health Administration patients with stage IV non-small-cell lung cancer foun…
Giving immunotherapy in the morning instead of the afternoon appears to help advanced lung cancer patients live longer, a large study found.