Regenerative medicine strategies show feasibility for dentin-pulp complex regeneration in dental pulp disease
New regenerative methods show promise for treating dental pulp disease
This mini-review examines regenerative medicine strategies, including stem cell biology and bioactive scaffolds, for treating dental pulp di…
New research explores how stem cells and advanced materials could help regrow damaged tissue inside teeth to improve long term outcomes.
High PTTG1 expression correlates with poorer survival and advanced disease in various solid tumors
High levels of PTTG1 protein linked to worse cancer outcomes
This meta-analysis of 22 studies from 21 articles analyzed the prognostic value of PTTG1 expression across multiple solid tumors. High PTTG1…
A review of 22 studies shows that high levels of the PTTG1 protein are linked to shorter survival times in several types of solid tumors.
FDA Approves Ibrance (palbociclib) for PIK3CA-Mutated Breast Cancer
FDA approves Ibrance combination for certain advanced breast cancer patients.
The FDA approved Ibrance (palbociclib) in combination with inavolisib and fulvestrant for endocrine-resistant, PIK3CA-mutated, HR-positive, …
The FDA approved Ibrance (palbociclib) with inavolisib and fulvestrant for adults with a specific type of advanced breast cancer that has a …
FDA Approves Ibrance (palbociclib) for HR-Positive, HER2-Negative Advanced Breast Cancer
FDA approves new drug Ibrance for certain advanced breast cancers.
The FDA approved Ibrance (palbociclib) for HR-positive, HER2-negative advanced or metastatic breast cancer in combination with an aromatase …
The FDA approved Ibrance (palbociclib) for adults with HR-positive, HER2-negative advanced or metastatic breast cancer. It is used with othe…
FDA Approves Trodelvy (sacituzumab govitecan-hziy) for HR+/HER2- Breast Cancer
FDA approves Trodelvy for a common type of advanced breast cancer.
The FDA approved Trodelvy for unresectable locally advanced or metastatic HR+/HER2- breast cancer after endocrine-based therapy and at least…
The FDA approved Trodelvy for adults with advanced HR-positive, HER2-negative breast cancer who have tried hormone therapy and at least two …
Low baseline TKa associated with longer OS of 38.5 months in endocrine-resistant MBC
Low thymidine kinase levels linked to longer survival in breast cancer
This translational analysis of a Phase III trial involving 555 patients with endocrine-resistant HR+ / HER2- metastatic breast cancer found …
A specific enzyme level called thymidine kinase may help doctors predict how well patients with certain types of breast cancer will respond …
Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
Zinc Mouthwash May Reduce Severe Mouth Sores From Radiation
Researchers evaluated the impact of topical and systemic zinc on the incidence of severe radiation-induced oral mucositis in head and neck c…
A new analysis suggests zinc mouthwash may cut the risk of severe mouth sores from radiation by 84%.
HPV prevalence in breast cancer tissue is 23% with higher risk in specific subtypes
Analysis shows link between HPV and breast cancer tissue
This meta-analysis of 82 studies involving 7,683 samples found a 23% prevalence of HPV in breast cancer tissues. The analysis identified sig…
A large analysis of over 7,000 samples reveals a significant link between the human papillomavirus and certain types of breast cancer.
Asparaginase therapy in acute lymphoblastic leukemia patients correlates with increased thromboembolism risk in specific subgroups
Adults with Leukemia Show Higher Risk of Blood Clots
This meta-analysis examined the incidence of thromboembolism among patients with acute lymphoblastic leukemia receiving asparaginase based c…
Patients with acute lymphoblastic leukemia treated with asparaginase face higher risks of blood clots, especially adults and those with spec…
Hybrid multi-component frameworks and qualitative integration characterize best practices in medical device risk management
Review Identifies Best Practices for Medical Device Risk Management
This scoping review analyzed 12 documents to identify best practices in medical device risk management. The authors found that while ISO 149…
New research highlights the need for more patient input and stakeholder engagement to improve safety in medical device manufacturing.
Robotic nipple-sparing mastectomy increases total operative time by 64.01 minutes compared to conventional techniques
Robotic surgery takes longer for breast reconstruction but keeps safety
This meta-analysis of prospective studies compares robotic versus conventional nipple-sparing mastectomy for patients undergoing immediate i…
Robotic-assisted breast reconstruction may take significantly longer than traditional methods, though it shows similar safety results for pa…
Cadmium exposure increases pancreatic cancer risk with an RR of 1.69 across meta-analyzed data
Cadmium exposure linked to 69% higher pancreatic cancer risk
This meta-analysis evaluates the link between cadmium exposure from various sources and pancreatic cancer incidence. The analysis found that…
People exposed to cadmium may face a 69% higher risk of pancreatic cancer, a new analysis finds.