Mendelian Randomization Evaluates IL-6 Inhibition Effects on Hepatocellular and Colorectal Cancer Risk
Genetic data shows tocilizumab does not cause specific cancers
Genetic modeling suggests that IL-6 inhibition does not causally increase the risk of hepatocellular or colorectal cancers in diverse popula…
New genetic modeling suggests the drug tocilizumab does not increase the risk of liver or colorectal cancers for patients.
Machine learning models provide statistically significant improvements in 5-year survival prediction for gastric cancer patients
AI Models Slightly Improve Gastric Cancer Survival Prediction
This systematic review and meta-analysis of 10 retrospective studies evaluated AI models using electronic health record data to predict 5-ye…
AI models modestly beat standard tools at predicting 5-year survival after gastric cancer surgery, a new meta-analysis finds.
FH-deficient uterine leiomyoma in young women requires IHC screening and lifelong renal surveillance
Rare Genetic Marker Linked to Multiple Uterine Fibroids
This case report and literature review describes a 35-year-old woman with multiple uterine leiomyomas confirmed as FH-deficient via immunohi…
A rare genetic condition can cause multiple uterine fibroids in young women and may require lifelong monitoring for other health issues.
Prostatic incidental uptake on FDG PET/CT has a 1.7% prevalence with 21.3% malignancy risk
New data helps doctors identify prostate cancer risks on scans
This meta-analysis of 24 studies evaluates the prevalence and malignancy risk of prostatic incidental uptake (PIU) on various radiotracers. …
Doctors are finding ways to better distinguish between harmless activity and actual cancer during routine prostate scans.
Hypopharyngeal well-differentiated liposarcoma can occur in young adults and may recur early after transoral excision
Rare Liposarcoma Can Recur Quickly After Surgery in Young Adults
This case report and literature review describes a 24-year-old man with a hypopharyngeal mass that was histopathologically confirmed as well…
A rare type of liposarcoma can appear in young adults and may return quickly after surgery, highlighting the need for careful monitoring.
Migrated pancreaticojejunal stents may act as chronic local irritants potentially linked to metachronous cholangiocarcinoma
Migrated Surgical Stent Linked to Late Cancer Diagnosis
This case report describes a 62-year-old male with metachronous hilar cholangiocarcinoma and an intraoperatively migrated pancreaticojejunal…
A single case report suggests that an old, migrated surgical stent may act as a local irritant leading to cancer.
Combination of Local Treatment and Systemic Therapy Improves Outcomes in Patients with Hepatocellular Carcinoma
Combining local and systemic treatments improves survival in liver cancer
This meta-analysis evaluated the addition of local treatments like TACE or HAIC to systemic therapy involving immune checkpoint inhibitors a…
Adding local treatments like TACE or HAIC to immunotherapy can improve response rates and extend survival for patients with hepatocellular c…
CSF IL-10 demonstrates high diagnostic accuracy and strong rule-in utility for CNSL
CSF IL-10 shows high accuracy in diagnosing brain lymphoma
This meta-analysis of 1462 patients evaluates the diagnostic performance of CSF IL-10 for central nervous system lymphoma. The analysis foun…
A new test using a protein called IL-10 in spinal fluid helps doctors identify central nervous system lymphoma with high accuracy.
Robot-assisted inguinal lymphadenectomy reduces the odds of total postoperative complications in penile cancer patients
Robot surgery may reduce complications for penile cancer patients
This meta-analysis of 276 patients with penile cancer compared robot-assisted inguinal lymphadenectomy (RAIL) to open surgery. RAIL was asso…
Robotic-assisted surgery shows a lower risk of overall complications for men undergoing lymph node removal for penile cancer, though evidenc…
Transoral robotic surgery and transoral laser microsurgery show higher 5-year survival than radiotherapy for supraglottic squamous cell carcinoma
Surgery Options Show Better Survival for Supraglottic Squamous Cell Carcinoma
This meta-analysis of 59 studies compared surgical techniques against radiotherapy for early stage supraglottic squamous cell carcinoma. Res…
New analysis shows that surgical techniques like robotic surgery may offer higher five-year survival rates for certain types of throat cance…
Transcutaneous electrical acupoint stimulation for intercostobrachial nerve syndrome: clinical trial protocol
Trial Plans to Test Acupoint Stimulation for Nerve Pain
This randomized controlled trial protocol describes a planned study of 200 patients with intercostobrachial nerve syndrome following breast …
A new clinical trial aims to see if electrical acupoint stimulation can help manage nerve pain after breast cancer surgery.
Explainable AI methods aim to improve deep learning interpretability in breast cancer ultrasound
New ways to make artificial intelligence clearer for breast cancer
This mini review summarizes Explainable Artificial Intelligence (XAI) methods for deep learning models in breast cancer ultrasound imaging. …
Doctors often struggle to understand how AI makes decisions. New methods aim to make these tools more transparent and reliable for ultrasoun…