Rituximab plus lenalidomide provides comparable progression-free survival to rituximab-based immunochemotherapy in advanced follicular lymphoma
Trial shows lenalidomide and rituximab for advanced follicular lymphoma
This Phase 3 randomized controlled trial of 1030 patients with previously untreated advanced follicular lymphoma found that the combination …
A large trial shows that a combination of two drugs can serve as an effective alternative to chemotherapy for patients with advanced follicu…
Tafasitamab plus lenalidomide and R-CHOP improves progression-free survival in high-risk DLBCL
Trial shows new treatment improves progression-free survival for lymphoma
This Phase 3 randomized, double-blind, placebo-controlled trial evaluated tafasitamab plus lenalidomide and R-CHOP in patients with high-ris…
A new drug combination showed improved progression-free survival for patients with high-risk large B-cell lymphoma in a Phase 3 clinical tri…
Serplulimab Combined With SOX Chemotherapy Improves Event Free Survival in Gastric Cancer
Trial shows serplulimab improves outcomes for gastric cancer patients
Neoadjuvant serplulimab plus SOX chemotherapy significantly improves event-free survival and safety profiles for PD-L1-positive gastric aden…
A new clinical trial finds that adding the drug serplulimab to chemotherapy significantly extends event-free survival for certain types of s…
Venetoclax-based combinations show superior progression-free survival compared to chemoimmunotherapy in CLL without TP53 aberrations
Trial shows venetoclax combinations improve progression-free survival in CLL
This Phase 3 randomized controlled trial of 926 patients with CLL without TP53 aberrations found that venetoclax-based regimens (RV, GV, and…
New clinical trial results show that specific venetoclax combinations can keep chronic lymphocytic leukemia stable for longer than standard …
Lung cancer screening identifies new solid nodules with a 7.4% malignancy rate at 12 months
New lung cancer screening data identifies risk for solid nodules
This multicenter randomized controlled trial evaluated lung cancer screening in 875 high-risk individuals aged 50-75 years. The study found …
A study of 875 high-risk individuals shows that the size and growth speed of new lung nodules can help predict cancer risk.
One-off 16 Gray stereotactic radiotherapy reduces anti-VEGF injections but results in worse visual acuity
Radiation for wet AMD cuts injections but harms vision
This randomized controlled trial of 411 patients with neovascular age-related macular degeneration found that one-off 16 Gray stereotactic r…
A single dose of radiation reduced the number of eye injections needed for wet AMD, but patients ended up with worse vision after four years…
Endovascular treatment does not improve functional outcomes but increases symptomatic intracranial hemorrhage risk in low NIHSS stroke
Endovascular Treatment Shows No Better Outcome For Certain Stroke Patients
This meta-analysis of patients with low NIHSS scores and Large Vessel Occlusion (LVO) found that endovascular treatment (EVT) did not improv…
A review of stroke treatments shows that endovascular treatment does not improve functional outcomes for some patients but may increase blee…
ACEIs and Beta Blockers Show Cardioprotective Effects in Chemotherapy
ACE Inhibitors and Beta Blockers May Protect Hearts During Chemotherapy
An umbrella review of 35 meta-analyses finds ACEIs and beta blockers modestly preserve cardiac function and reduce heart failure risk during…
Specific heart medications like ACE inhibitors and beta blockers may help protect heart function in patients undergoing chemotherapy treatme…
Robotic-assisted CT-guided transthoracic needle biopsy reduces radiation exposure and complication rates for pulmonary nodules
Robotic-assisted biopsy shows lower radiation and fewer complications
This meta-analysis evaluates robotic-assisted versus conventional CT-guided transthoracic needle biopsy for pulmonary nodules. The analysis …
A new look at lung nodule biopsies shows that robotic tools can reduce radiation exposure and complication rates for patients.
Statin use and EGFR-TKI efficacy in EGFR-mutant non-small cell lung cancer remains to be evaluated
Statins may boost lung cancer treatment, review planned
This protocol for a systematic review and meta-analysis aims to evaluate if statin exposure is associated with improved outcomes in patients…
A new review will examine if statins improve survival in EGFR-mutant lung cancer patients on targeted therapy.
Radiotherapy with re-irradiation achieves long-term remission in orbital Rosai-Dorfman disease
Radiotherapy Shows Promise for Orbital Rosai-Dorfman Disease Treatment
This case report describes a 58-year-old man with orbital Rosai-Dorfman disease who achieved complete remission for five years after initial…
A patient with orbital Rosai-Dorfman disease saw significant improvement in vision and remission after undergoing targeted radiation therapy…
Intratumoral microbiome linked to survival and chemotherapy resistance in pancreatic cancer
Tumor Bacteria Linked to Pancreatic Cancer Survival
This systematic review synthesizes evidence that the intratumoral microbiome in pancreatic cancer is mainly composed of Proteobacteria and F…
Bacteria inside pancreatic tumors may influence how long patients live and how well chemo works.