PD-1 and PD-L1 inhibitors increase the risk of skin rash in cancer patients
Immunotherapy drugs increase rash risks for cancer patients
This meta-analysis evaluated the risk of developing rashes in cancer patients treated with PD-1 or PD-L1 inhibitors, both alone and in combi…
New data shows that certain immunotherapy drugs used to treat cancer significantly increase the risk of developing skin rashes.
Lead-in ADT reduces grade ≥3 neutropenia incidence in metastatic hormone-sensitive prostate cancer patients
Lead-in therapy may reduce severe low white blood cell counts
This post hoc analysis of a phase 3 trial and real-world validation study evaluated lead-in androgen-deprivation therapy (ADT) for patients …
A new look at clinical data suggests that a lead-in hormone treatment can help prevent serious low white blood cell counts in prostate cance…
Dabrafenib and trametinib produce rapid response in a single case of BRAF V600E-mutant PHC
Targeted Treatment Shows Promise for Rare Pancreatic Cancer Type
This systematic review and case report analyze pancreatic hepatoid carcinoma (PHC) and the role of targeted therapies. The analysis identifi…
A specific drug combination showed a rapid and deep response in a patient with a rare type of pancreatic cancer involving a BRAF mutation.
CAR T-cell therapy targeting CD19 or BCMA may induce sustained remission in specific autoimmune diseases
CAR T-cell Therapy Shows Potential for Autoimmune Disease Remission
This systematic review examines CAR T-cell therapies for patients with systemic lupus erythematosus, idiopathic inflammatory myopathy, and s…
A new type of cell therapy may offer a way to reset the immune system in patients with lupus, scleroderma, and inflammatory myopathy.
Deep learning models achieve 0.979 AUC for colorectal cancer detection in histopathological whole-slide images
Deep Learning Models Show High Accuracy for Colorectal Cancer Detection
This meta-analysis evaluates the diagnostic accuracy of deep learning models for detecting colorectal cancer in histopathology slides. The a…
New analysis shows deep learning models can identify colorectal cancer in tissue images with high sensitivity and specificity.
TORS yields oncologic outcomes comparable to radiotherapy in early-stage oropharyngeal cancer
Robotic surgery shows promise as an alternative to radiation therapy
This systematic review of 51 clinical trials found that transoral robotic surgery (TORS) achieves oncologic outcomes comparable to radiother…
Robotic surgery may offer a way to reduce treatment intensity for some patients with throat cancer while maintaining survival rates.
Exercise interventions improve sleep quality in breast cancer survivors with larger effects for yoga and longer durations
Exercise and yoga may improve sleep for breast cancer survivors
This systematic review and meta-analysis of 31 randomized controlled trials found that exercise interventions may improve sleep quality in b…
New data shows that regular exercise, including yoga, can help breast cancer survivors achieve better sleep quality.
Repeat ablation provides favorable outcomes for local recurrence after primary ablation in renal cell carcinoma
Local treatments show mixed results for recurring kidney cancer
This meta-analysis of 45 studies evaluates the efficacy of various local salvage therapies for patients with local recurrence of renal cell …
New data shows that while some local treatments work well for recurring kidney cancer, others face challenges with distant spread.
Sarcopenia triples dysphagia odds across cancers, meta-analysis finds
Muscle Loss Linked to Swallowing Problems in Cancer Patients
This meta-analysis of 2,889 patients with cancer, including head and neck cancer, found that tumor-associated sarcopenia is significantly as…
A new analysis finds that cancer patients with muscle loss are nearly three times more likely to have swallowing difficulties, regardless of…
Wasting is associated with higher chemotherapy toxicity and reduced survival in pediatric cancer patients
Malnutrition in Pediatric Cancer Patients Linked to Poorer Outcomes
This meta-analysis of 2,419 pediatric cancer patients in Africa found a wasting prevalence of 39.7% (95% CI: 30.7%-49.1%). The study indicat…
Nearly 40% of pediatric cancer patients in Africa face wasting or malnutrition, which is linked to higher toxicity and lower survival rates.
Disease-free survival shows strong correlation with overall survival in localized renal cell carcinoma
Disease free survival predicts long term outcomes for kidney cancer
This systematic review and trial-level meta-analysis of 9594 patients with localized renal cell carcinoma found a strong correlation between…
A large analysis shows that tracking how long patients stay cancer-free can help doctors predict overall survival in kidney cancer cases.
Radiomics models show moderate accuracy for predicting microsatellite instability status in gastric cancer patients
Imaging data helps predict specific markers in gastric cancer
This meta-analysis of 2447 patients evaluates the use of radiomics for preoperative prediction of microsatellite instability (MSI) status in…
New imaging analysis tools can help doctors identify a key genetic marker in stomach cancer patients before surgery begins.