PM-TRPV4 positivity associated with invasive progression in patients with ductal carcinoma in situ
New Protein Test Predicts Which Breast Lesions Spread
This retrospective case-control study evaluated 44 patients with pure ductal carcinoma in situ (DCIS) to assess PM-TRPV4 status. PM-TRPV4 po…
A new protein test on cell walls helps doctors predict which early breast changes might spread to invasive cancer.
Meta-analysis finds oral SERDs improve PFS over standard ET in HR+ HER2- ABC
New Drug Helps Some Breast Cancer Patients Live Longer
This systematic review and meta-analysis of 2,808 patients with HR+ HER2- advanced breast cancer found oral SERDs improved progression-free …
New oral pills help some advanced breast cancer patients live longer and fight back against drug resistance by blocking estrogen growth sign…
Systematic review and meta-analysis on incidental findings in trauma whole-body CT scans
Hidden Injuries Found in Trauma Scans
This systematic review and meta-analysis synthesized data on incidental findings from trauma whole-body CT scans. The authors found that inc…
Nearly 30% of trauma scans reveal hidden injuries needing treatment in adults, not children, requiring new safety rules for emergency rooms.
Online mindfulness-based cognitive therapy reduces distress in cancer patients over 9-month follow-up.
Cancer Patients Find Lasting Calm With Simple Online Mindfulness
This secondary analysis of a randomized controlled trial evaluated online mindfulness-based cognitive therapy (eMBCT) in 161 cancer patients…
Simple online mindfulness tools offer lasting mental relief for cancer patients.
Narrative review offers qualitative synthesis without reported quantitative outcomes or safety data.
Making Cancer Drugs Work Better: The New Roadmap Ahead
This source is a narrative review with no reported study population, sample size, or specific interventions. The authors provide qualitative…
Doctors are mapping four new ways to make immune cancer drugs work better for patients whose tumors hide from the body's defenses.
Review of STING agonists for high-grade and diffuse midline glioma discusses systemic toxicity and delivery constraints.
New Brain Drug Target Could Wake Up the Immune System
This narrative review examines the potential of STING agonists, cyclic dinucleotides, and related compounds for treating high-grade glioma a…
A new brain drug target aims to wake up the immune system's defenses against dangerous, hard-to-treat tumors that hide from the body's natur…
Probiotics shorten hospital stay and improve gut recovery after open gastrectomy for gastric cancer
Probiotics may shorten hospital stay after gastric cancer surgery in small trial
In a single-centre randomized controlled trial of 42 patients undergoing open gastrectomy for gastric cancer, 10 days of postoperative probi…
Taking probiotics after open gastric cancer surgery may help patients leave the hospital sooner and recover their gut function faster.
Peer-led blended peer support program improves psychosocial adjustment in young- to middle-aged breast cancer patients
Can a peer support program help young breast cancer patients cope better after surgery?
In a single-center cluster RCT of 70 young- to middle-aged breast cancer patients, an 8-week peer-led, nurse-involved blended peer support p…
An 8-week peer support program helped young breast cancer patients feel more socially supported and face problems head-on after surgery.
Narrative review examines driver mutations and immunotherapy response in non-small cell lung cancer
Does your lung cancer's genetic makeup change how well immune therapy works?
This narrative review explores how targetable driver gene alterations in non-small cell lung cancer (NSCLC) influence the tumor immune micro…
Lung cancer's genetic drivers actively reshape the tumor's immune environment, causing immunotherapy to work differently depending on a pati…
Extensive intraoperative peritoneal lavage after gastrectomy for gastric cancer with peritoneal cytology positivity.
Can washing the belly during surgery help prevent stomach cancer from coming back?
This single-arm exploratory phase 2 trial in 13 patients with gastric cancer and positive peritoneal cytology evaluated extensive intraopera…
A thorough belly wash during stomach cancer surgery kept patients free from recurrence for 14.5 months if their fluid tests showed no cancer…
Switching therapy after rituximab resistance in AQP4-IgG+ NMOSD shows variable relapse outcomes.
New Hope for Tough-to-Treat Nerve Disorder
This single-center, retrospective case series of 10 adults with AQP4-IgG+ NMOSD who were resistant to rituximab evaluated switching therapy.…
Patients with a rare nerve disease who stopped responding to standard treatment found relief after switching to new therapies that prevented…
SBRT with ≥70 Gy BED10 for colorectal liver metastases shows 74.5% 1-year FFLP
Can a higher radiation dose improve tumor control in liver metastases?
This retrospective cohort study of 116 patients with colorectal liver metastases treated with stereotactic body radiation therapy (SBRT) fou…
For liver cancer spread from colorectal cancer, higher radiation doses to tumors significantly lower the risk of regrowth, while multiple tu…