Clinical Trial Search

Primary: Change in Pain Assessment — 2.9; 4.0 score on a scale

Primary: NRS-Pain With Movement on POD 2 — 2.83 units on a scale

Primary: Change in Pain: Visual Analog Scale (VAS) — 2.1 units on a scale (centimeters)

Primary: Credibility and Expectancy Questionnaire (CEQ)- Credibility Subscale — 8 Participants

Primary: 10 Day Silverman Integrated Analgesic Assessment (SIA) Score — 1.4; -1.4 score on a scale — p=0.7957

Primary: Safety and Tolerability as Assessed by Number of Participants With Treatment-Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs) — 94; 2 Participants

Primary: Severity of Acute Pain — 46; 31 mm — p=0.05

Primary: Analgesic Efficacy — 26.5; 32.3 percentage of patients with NRS≥4

Primary: Number of Patients Who Respond to Study Medication at the 24-hr Numeric Pain Rating Scale (NPRS) Assessment Compared to Placebo. — 47; 61; 56; 37 Participants

Primary: Change in Pain Score at 60 Minutes — 2.18; 4.01 units on a scale

Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale

Primary: Time Until PCA Discontinued After the Operation — 76.4; 86.7 hours

Primary: Change of Pain Relief From Baseline to the End of Treatment Using the 5-point Visual Rating Scale (VRS) — 3; 23; 28; 20 Participants

Primary: Number of Patients That Experienced a Treatment-emergent Adverse Event — 490 Participants

Primary: Time-weighted Sum of the Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) at Rest 0 to 48 Hours (SPIDr0-48) After the First Dose of…

Primary: Intervention Effects on Mechanical Sensitivity Threshold — 125.6; 93.56; 63.04; 70.27 100*Value at 24 hours/Value at Baseline

Primary: Postoperative Pain Intensity — 33; 42 Participants

Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg

Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale

Primary: Sum of Pain Intensity Difference (SPID) for Low Back Pain - Summary Statistics at 120 Hours (With Imputation) — 264.6; 264.0 Units on a scale — p=0.9703

Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934

Primary: Change in Pain Intensity, Baseline to 60 Minutes After Medication Infused — 5.8; 5.2 units on a scale

Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01

Primary: Change From Baseline of Pain as Described by Numeric Rating Scale (NRS) [Minimum:0, Maximum 10] at 15 Minutes — 3.5; 6.0 units on a scale

Primary: Sum of Pain Intensity Differences (SPID) Over 48 Hours — 65.3; 131.7; 154.5 Scores on a scale — p=<0.001

Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05

Primary: Clinical Improvement in NRS Pain Score — 62; 63 Participants

Primary: Change in Pain Score — -0.92; -0.16; -1.24 score on a scale

Primary: Verbally Administered Numeric Rating Scale (VNRS) — 68; 66 units on a scale — p=0.56

Primary: Mean Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) of Pain Intensity Scores From Time 0 (When First Dose on Day 1 is Administered) Through 24 Hours…