N/A N=117 Luminopia One Amblyopia Vision Improvement Study
Amblyopia
Primary: Best-Corrected Visual Acuity of Amblyopic Eye — 1.77; 0.85 Lines of visual acuity improvement
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=139 Levodopa for the Treatment of Residual Amblyopia
Amblyopia
Primary: Distribution of Amblyopic Eye Visual Acuity Change From Baseline — 0; 0; 2; 1 participants
N/A N=76 New Visual Acuity and Crowding Tests for Better Detection of Amblyopia
Amblyopia
Primary: Visual Acuity (LogMAR) — 0.004; 0.551; 0.320; 0.005 logMAR
Phase 3 N=233 Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds
Amblyopia
Primary: Distribution of Visual Acuity in the Amblyopic Eye at 17 Weeks — 0; 0; 0; 0 participants
N/A N=146 Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old
Amblyopia
Primary: Mean Amblyopic Eye Visual Acuity Improvement With Spectacles — 2.3; 3.2 logMAR units
Phase 3 N=73 Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
Amblyopia
Primary: Distribution of 10-week Amblyopic-Eye Visual Acuity — 0; 1; 2; 0 participants
Phase 2 N=33 Pilot Study to Evaluate Levodopa as Treatment for Residual Amblyopia
Amblyopia
Primary: Distribution of Amblyopic Eye Visual Acuity Letter Scores at 9 Weeks After Starting Levodopa — 2; 5; 2; 0 participants
Phase 3 N=240 Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old
Amblyopia
Primary: Visual Acuity Mean Score in the Amblyopic Eye — 0.23; 0.22; 0.54; 0.50 logMAR units — p=0.21
N/A N=485 Study of Binocular Computer Activities for Treatment of Amblyopia
Amblyopia
Primary: Change in Distance Visual Acuity From Baseline in the Younger Cohort (5 to <13 Years) — 1.05; 1.35; 1.08; 1.32 LogMAR lines
N/A N=320 Binocular Dig Rush Game Treatment for Amblyopia
Amblyopia
Primary: Mean Change in Amblyopic-eye Visual Acuity (VA) Older Cohort — 1.3; 1.7; 1.3; 1.7 Letter score — p=0.71
Phase 3 N=186 Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children
Amblyopia
Primary: Distribution of Visual Acuity in the Amblyopic Eye at 24 Weeks — 1; 0; 3; 0 participants
N/A N=318 Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening
Amblyopia · Strabismus
Primary: Detection of Amblyopia and Strabismus in Children Ages 2-5 Using Automated Pediatric Vision Scanner Device — 6; 249; 0; 45 Participants
Phase 3 N=169 Increasing Patching for Amblyopia in Children 3 to < 8 Years Old
Amblyopia
Primary: Distribution of 10-week Amblyopic Eye Visual Acuity — 1; 0; 0; 0 participants
N/A N=559 Observation Versus Occlusion Therapy for Intermittent Exotropia
Exotropia
Primary: Deterioration by 6 Months - Older Cohort — 10; 1; 7; 1 Participants — p=0.004
N/A N=92 A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
Amblyopia · Ocular Motility Disorders
Primary: Visual Acuity — -0.12; -0.13 change in logMAR
N/A N=40 Symmetric vs Asymmetric BLR Recession in Management of Basic IXT With Ocular Dominance
Intermittent Exotropia
Primary: Ocular Alignment at Distant Fixation — 5.8; 1.1 prism diopter
N/A N=35 Enhancement of Emmetropization in Highly Hyperopic Infants
Hyperopia
Primary: Central Cycloplegic Refractive Error With Retinoscopy — 1.6; 1.2; 2.8 Diopters
N/A N=49 Bifocal & Atropine in Myopia (BAM) Study
Refractive Errors
Primary: Refractive Error Progression — -3.50 Diopter — p=0.70
N/A N=217 A Prospective Observational Study of Adult Strabismus
Convergence Insufficiency · Divergence Insufficiency · Hypertropia
Primary: Number of Participants With Symptom Success at 10 Weeks — 25; 91; 12 Participants
N/A N=249 Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation
Hyperopia
Primary: Number of Participants With Confirmation of Failure Criteria — 5; 4; 11; 18 Participants — p=0.72
Phase 3 N=187 Low-Dose Atropine for Treatment of Myopia
Myopia
Primary: Treatment Group Comparison of Change in Spherical Equivalent Refractive Error. — 0; 0; 1; 0 Participants
Phase 2 N=97 Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia
Primary: Axial Length at 36 Months — 25.28; 25.25; 25.33 mm
Phase 2 N=45 Trial of L-DOPA as a Treatment to Improve Vision in Albinism
Albinism
Primary: Improved Vision — 0.67; 0.55; 0.53 logMAR
Phase 2 N=65 Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia
Presbyopia
Primary: Percentage of Participants With at Least a 2 Line Improvement From Baseline in Uncorrected Near Visual Acuity (UNVA) in the Non-Dominant Eye — 46.7; 70.6; 56.3; 68.8…
N/A N=58 A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Intermittent Exotropia
Primary: Mean Distance Exotropia Control Score — 2.0; 2.8 points on control score scale — p=0.01
Phase 3 N=73 Full-Time Occlusion Therapy for Intermittent Exotropia in Children
Intermittent Exotropia
Primary: Number of Participants With a Change in Mean Distance Control Scores at 3 Months — 1; 0; 4; 4 Participants
N/A N=91 Mobile Medical Application for Cost-effective Strabismus Screening
Strabismus
Primary: Comparison of App-measured Eye Deviation Angles to Gold Standard — 3.3 prism diopter
N/A N=48 Visual Restoration for Hemianopia
Stroke Induced Vision Loss · Hemianopia · Quadrantanopia
Primary: 24-2 Humphrey PMD Change From Baseline to 6-month Post-training Timepoint — 0.84; 0.10; 0.58; 0.12 decibels