Clinical Trial Search

Primary: Association Between EEG Measurements and Default Mode Network Brain Activity Measured With fMRI — 0.09 Spearman rank correlation coefficient

Primary: Behavioral Performance (Accuracy) on Cognitive Tests of Perceptual Processing — 97; 98; 98 percent correct

Primary: dACC BOLD Signal (After Active rTMS Session) — -1.14; -1.27 Percentage of BOLD signal change

Primary: Number of Remembered Items — 1.72; 1.68; 1.68; 1.65 remembered items — p=0.783

Primary: Number of Remembered Items — 1.863; 1.754; 1.796; 1.797 number of remembered items — p=0.263

Primary: 2-back Minus 1-back Blood Oxygen Level-Dependent (BOLD) Activation, Voxelwise in FPN — 0.74; 0.75; 0.58 arbitrary units — p==0.11

Primary: Duration of Cortical Silent Period (CSP) (ms) — 104.34; 99.71 milliseconds (ms)

Primary: Change in NIH Toolbox Fluid Cognition Composite Score — 4.7; 6.1 units on a scale

Primary: Functional Connectivity (FC) Changes Between the Left Hippocampus and Left Parietal Cortex — -0.03; 0.13; 0.02; -0.01 Change in z-transformed R-value

Primary: Memory Performance — 0.89; 0.64; 0.91; 0.66 proportion accuracy

Primary: Threshold-Level Tactile Detection Hit Rate — 0.37; 0.46; 0.47; 0.32 # hit trials/(total # hit + miss trials) — p=0.0031

Primary: Acute Effect of a rTMS Session on the Performance for a Working Memory Task, as Measured by Accuracy (in Percentage) — 50.43; 55.42; 83.93; 46.49 percentage of accuracy

Primary: Cognition on the RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) Scale — 7; 5.25; -1.5; -1.33 units on a scale

Primary: Cognitive and Memory Function — 56.5; 49.8 score on a scale

Primary: Relative Changes in Corticolimbic Functional Connectivity as a Result of TMS — -0.11; -0.19 Fisher transformed z values

Primary: Composite Score of Attention and Executive Functioning From a Neurocognitive Test Battery — 0.18; -0.06 units on a scale

Primary: Change in Hippocampal-dependent Learning — -.00369; .00404 learning rate (proportion correct/trial) — p=<.05

Primary: Changes in Thalamocortical Functional Connectivity (FC) — 22.7; 20.5; 21.9 arbitrary units

Primary: Relationship Between Prefrontal Cortex Activation and Respiratory Sinus Arrhythmia — -0.064; 0.00375 Micro mol per second — p=0.008

Primary: Change From Baseline in Resting-state Functional Connectivity Between the Caudate and the Caudate Network — -0.073; -0.021; -0.029; -0.007 Fisher Z-Transformation Score

Primary: Change in Montgomery and Asberg Depression Rating Scale (MADRS) — 33.28; 16.23 score on a scale — p=<0.001

Primary: Change of Daily Step Counts From Baseline — 842; 194; 1099; 408 Steps per day — p=0.009

Primary: Improvement in Cognitive Ability. — 4.7; 4.5 units on a scale — p=<0.05

Primary: Change in Brain Nicotinamide Adenine Dinucleotide Metabolites NAD+/NADH — -0.79 ratio

Primary: Cortical Excitability: Resting Motor Threshold (RMT). — 51.1; 51.8 % of Max Stimulation Output (MSO)

Primary: ROBoT-r Task Performance Score (During Stimulation) — 73.19; 75.33; 76.64; 77.62 score on a scale (0-100) — p=0.049

Primary: Change in Clinical Disease Severity (CDR) — -0.1; 0.0; 0.0; 0.0 score on a scale

Primary: Motor-evoked Potential (MEP) Amplitudes — 1.13; 0.96; 0.90 arbitrary units (normalized microvolts)

Primary: Change in Resting State Network

Primary: N-Back Working Memory — .2030; .0731 percent change