N/A N=47 Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia
Cystic Fibrosis
Primary: Accuracy of CO2 Levels — 48.9; 39.5; 41.5; 44.3 mmHg
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=286 A New and Innovative Method for CO2 Removal in Anesthetic Circuits
Anesthesia
Primary: End-tidal CO2 Concentration (%) — 5.069; 5.096 % end-tidal CO2
N/A N=23 Optical Imaging Measurement of Intravascular Solution Efficacy Trial
Peripheral Artery Disease
Primary: Quality of Images — .702; .872; .10; .743 Clear imaging field (CIF) proportion
N/A N=21 Absorptive Clearance in the Cystic Fibrosis Airway
Cystic Fibrosis
Primary: Absorptive Clearance Rate — 42; 32 percentage of DTPA absoprtion per hour
N/A N=100 Study of Carbon Dioxide Exchange Patterns During Robotic Prostatectomies
Prostate Cancer · Pneumoperitoneum
Primary: Intraoperative Pneumoperitoneal Pressure (mmHg) — 7.9; 9.9 mmHg — p=<0.001
N/A N=27 Carbon Dioxide (CO2) and Cognitive Impairment
Healthy
Primary: Change in PMN (Polymorphonuclear Leukocyte) Activation as Measured by Basal Oxygen Consumption (OCR) — 18.74; 19.54 pmol/min
N/A N=49 Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)
Delivery Room Resuscitation
Primary: PCO2 Level Outside of Desired Range (40-60 mmHg) — 9; 8 participants
N/A N=20 A Study to Determine if Carbon Dioxide Lavage During Total Knee Surgery Reduces Intraoperative Embolic Events
Postoperative Complications · Memory Disorders
Primary: The Number of Cerebral Emboli During Surgery as Measured by Transcranial Doppler (TCD) — 0; 3 emboli
Phase 2 N=147 Market Potential of Carbon Dioxide Nasal Spray
Nasal Congestion
Primary: Which One Product That Relieves Nasal Congestion do You Buy Most Often? — 46; 29; 6; 3 Participants
Phase 1 N=10 Clearance of 25-hydroxyvitamin D in Cystic Fibrosis
Cystic Fibrosis
Primary: Metabolic Clearance of D6-25(OH)D3 — 397; 342 mL/day
N/A N=32 Carbon Monoxide Measurement to Screen for Sickle Cell Disease
Sickle Cell Anemia
Primary: End-Tidal Carbon Monoxide — 4.35; .80 ppm
N/A N=29 A Comparison of Capnography Sampling Lines
Capnography
Primary: Capnography Measured CO2 Waveform Data as a Function of CO2 Cannula Sampling Filterline (CCSF) Stratified by Activity — 30.6; 0.0; 26.6; 0.2 mmHg
N/A N=6 Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia
Anesthetic Ventilatory Requirements
Primary: Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas. — 136 mL
Phase 3 N=350 Breath Analysis Technique to Diagnose Pulmonary Embolism
Pulmonary Embolism
Primary: Phase I: Percentage Change in the Postoperative End Tidal CO2/O2 Ratio and D-dimer Concentration Relative to the Preoperative Measurement — 0; 136 percent change
N/A N=52 Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
Lung Cancer · Pulmonary Nodule, Solitary · Segmentectomy
Primary: The Intersegmental Border Appearance Time During the Surgery. — 748.74; 157.11 seconds
N/A N=8 Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers
CO2 Clearance · Mask Comfort · Rebreathing Exhaled Gas
Primary: Carbon Dioxide Clearance From the Masks — 1.83; 1; 0.49; 0 percentage of CO2 inspired
N/A N=77 Minimally Invasive Cardiac Output Monitoring Device
Cardiac Event
Primary: Establishment of a Dataset to Create an Algorithm to Measure Cardiac Output — 75; 2 Participants
N/A N=200 Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant
Endoscopy
Primary: Number of Procedures With Elevated End-tidal CO2 Levels — 8; 21 Procedures
N/A N=32 Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients
Sepsis
Primary: Change in Breath Delta Value — 0.44 parts per mil (‰)
Phase 1 N=88 Clearance of 25-hydroxyvitamin D in Chronic Kidney Disease
Chronic Kidney Disease
Primary: Metabolic Clearance of D6-25(OH)D3 — 360; 313; 263 milliliter per day (ml/d)
N/A N=90 Respiration Rate V2.0 in a Hospital Setting
Respiratory Rate
Primary: Mean Error (ME) +/- 1 Breath Per Minute, RR Sensor — -0.82 BrPM (breaths per minute)
N/A N=30 Respiration Rate V2.0 in Healthy Volunteers
Focus of the Study is Measuring Respiratory Rate
Primary: Mean Error (ME) +/- 1 Breath Per Minute, RR Sensor — -0.05 BrPM
Phase 1 N=20 Absorptive Clearance After Inhaled Osmotics in Cystic Fibrosis
Cystic Fibrosis
Primary: Absorptive Clearance Rate After Isotonic Saline Inhalation — 32.0 percent cleared / 80 minutes
N/A N=20 CO2 Versus Lund De-airing Technique in Heart Surgery
Aortic Valve Disorder
Primary: Number of Air Microemboli Registered Over the Middle Cerebral Arteries by On-line Trans-cranial Echo-Doppler (TCD). — 41; 118 Air Microemboli — p=<0.01
N/A N=25 Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy
Liver Cancer
Primary: CO Output (Ppm) — 2.03 ppm
N/A N=262 Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
Right Colon Adenoma Miss Rate · Right Colon Hyperplastic Polyp Miss Rate
Primary: Percentage of Adenomas and Hyperplastic Polyps Missed During Initial Right Colon Examination — 18.0; 36.7 percentage of all missed polyps
N/A N=13 Intranasal CO2 for Allergic Rhinitis
Allergic Rhinitis
Primary: Change From Diluent Challenge Contralateral Secretion Weight at Antigen Challenge — 6; 19.6 milligrams
N/A N=33 Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD
Congenital Heart Disease
Primary: Mean Difference in Stroke Volume Between CMR and SMIC — 1.7 ml — p=0.47
N/A N=10 Measurement of Kidney Blood Flow and Oxygen Levels by MRI
Chronic Kidney Disease
Primary: Measurement of Renal Blood Flow of the Kidney by the PAH Method — 190 ml/min
N/A N=132 AirSeal®Insufflation Trocar/CO2 Absorption Study
Gynecologic Diseases
Primary: Average Carbon Dioxide (CO2) Absorption During Gynecologic Laparoscopy Using the AirSeal® Versus Standard Trocars at Intra-abdominal Pressures of 10 mmHg — 3.96; 4.05…