N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=300 Sedation Regimens in GI Endoscopy
Anesthesia · Endoscopy · Colonoscopy
Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Phase 2 N=15 Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients
Acute Respiratory Failure · Anxiety
Primary: Aggregate Sedative Exposure During PCS Use (up to 5 Days). — 4; 3.5 units on a scale
Phase 3 N=50 Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Gastrointestinal Disease
Primary: Consumption of Rescue Patient Controlled Propofol — 42.4; 28.6 mg
Phase 4 N=107 Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department
Pain
Primary: Patients With Clinical Signs of Respiratory Depression or Sub Clinical Respiratory Depressions Measured by Capnography and Pulse Oximetry. — 22; 21 Participants
N/A N=110 Sedline EEG Guided Depth of Anesthesia
Anesthesia · Surgery
Primary: Total Average Anesthetic — 1.1890; 1.2906 percentage of sevoflurane
Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants
N/A N=150 Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
Sedation, Bronchoscopy
Primary: Discharge Assessment Using PADSS After 2 Hours Number of Patients Reaching PADSS Score 10 After 2 Hours — 19; 30; 45 Participants
Phase 4 N=126 Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
Sedation
Primary: Number of Participants With Sub-clinical Respiratory Depression and Clinical Events Associated With Respiratory Depression During the Sedation Procedure — 11; 12…
N/A N=86 Sedation and Pain (The Effect of IV Sedation on Pain Perception)
Pain
Primary: Pain Rating Change — -0.253; 0.762; -0.346 units on a scale
Phase 4 N=40 Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation
Intubation; Difficult
Primary: Endoscopy Scores — 3; 2 units on a scale
Phase 4 N=144 A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
Anesthesia
Primary: Respiratory Events Requiring Intervention — 17; 2 Participants
N/A N=11 Sedation in Patients at Risk for Upper Airway Collapse
Obstructive Sleep Apnea
Primary: Respiratory Disturbance Index — 57.52; 21.32 events per hour
Phase 4 N=271 Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation
Procedural Sedation
Primary: Clinical Interventions During Sedation — 41; 33; 48 Clinical interventions performed
Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
N/A N=39 Nitrous Oxide Versus Intravenous Sedation for Anesthesia
Pregnancy Termination in Second Trimester
Primary: Visual Analog Scale (VAS) Score for Maximum Procedural Pain — 54.1; 34.0 units on a scale
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
Phase 3 N=1,000 Safety and Effectiveness of a Computer-Assisted Personalized Sedation (CAPS) Device for Propofol Delivery During Endoscopy
Colonoscopy · Endoscopy, Digestive System · Conscious Sedation
Primary: Area Under the Curve for Oxygen Desaturation (AUCDesat) — 23.6; 88.0 seconds*percent of oxygen desaturation — p=0.028
Phase 4 N=114 Propofol and Dexmedetomidine Versus a Propofol Only Regimen for Sedation During Colonoscopy
Colonoscopy
Primary: Percentage of Subjects Ready for Discharge in Each Group at 30 Minutes Post Procedure — 26; 44 Participants
Phase 3 N=60 A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Anxiety, Dental · Dental Decay
Primary: Incidence of Adverse Sedation-Related Events in Musculoskeletal System During Sedation — 2.8; 3; 2.5500 score on a scale — p=0.016
Phase 4 N=500 Bispectral Index-guided Sedation for Flexible Bronchoscopy
Flexible Bronchoscopy
Primary: The Number of Participants With Any Hypoxemia Event During Flexible Bronchoscopy — 97; 88 participants — p=0.05
N/A N=111 Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
Hypoxia · Endoscopy · Anesthesia Morbidity
Primary: Hypoxia Rate as Assessed by Number of Participants With at Least One Hypoxic Event — 3; 16 Participants
N/A N=10 Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
Conscious Sedation · Deep Sedation · Critical Care
Primary: Amplitudes (in Micro Volts) of Acoustic Event Related Potentials (Time-locked Amplitudes in the Electroencephalogram 100 Milliseconds After the Acoustic Stimulus…
N/A N=43 Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults
Joint Dislocation · Perianal Abscess · Abscess
Primary: Total Number of Respiratory Depression Events — 0 events
Phase 4 N=68 Etomidate vs. Midazolam for Sedation During ERCP
Choledocholithiasis · Cholangiocarcinoma · Pancreatitis
Primary: Number of Intervention — 1.9; 7.5 Number of intervention — p=0.05
Phase 4 N=60 A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
Conscious Sedation · Simple Lacerations Less Than 4 cm · Lumbar Punctures
Primary: ED Length of Stay After Intranasal Midazolam or Nitrous Oxide Administration — 24.5; 18.5; 9; 10 minutes
Phase 4 N=140 Propofol Administered by Gastroenterologists by Target Controlled Infusion Pump During Endoscopy
Sedation · Endoscopy
Primary: Endoscopist's Satisfaction (Visual Analog Scale) About Sedation — 93; 83; 98; 87 units on a scale
N/A N=19 Effects of Audiovisual Distraction on Desaturation and Airway Intervention in OSA-patients
Obstructive Sleep Apnea (OSA)
Primary: Desaturations — 0; 1 number of desaturation events