N/A N=300 Investigational Multi-purpose Contact Lens Care Solution.
Contact Lens Wear
Primary: Slit Lamp Findings — 11; 16; 0; 0 Subjects Eyes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=295 Vistakon Investigational Multi-purpose Contact Lens Care Solution.
Contact Lens Wear
Primary: Slit Lamp Findings (SLF) — 0; 0; 0; 0 eyes (2 per subject)
N/A N=444 Study of A New Contact Lens Cleaning and Disinfecting Solution
Vision Disorders
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 4; 0 eyes
N/A N=236 Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions
Contact Lens Solutions
Primary: Overall Comfort Score (Senofilcon A Lens) — 64.42; 59.73; 63.75; 63.47 units on a scale
N/A N=295 A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution
Refractive Ametropia
Primary: Overall Comfort Averaged Over All Follow-up Visits — 91.7; 90.7 score on a scale
N/A N=32 A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand
Corneal Staining
Primary: Corneal Staining Severity — 0.01; 0.01; 0.02; 0.01 units on a scale
N/A N=177 Evaluation of a Multi-Purpose Solution
Contact Lens Solutions
Primary: Antimicrobial Efficacy — 114; 219; 0; 3 Eyes
N/A N=396 A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution
Contact Lens Wear
Primary: The Primary Safety Endpoint Was Statistical Non-inferiority With Respect to the Proportion of Eyes With Any Slit Lamp Findings Greater Than Grade 2 at Any Visit Between…
N/A N=438 A Study to Evaluate a Modified Contact Lens
Myopia
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 0; 0 eyes
N/A N=30 BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
Myopia
Primary: Ocular Health - Corneal Staining — 38; 35; 18; 20 Eyes
N/A N=352 Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
Myopia · Astigmatism · Hyperopia
Primary: Percentage of Subjects With Visibly Clean Lenses — 44.5; 39.8; 35.0; 31.3 percentage of subjects
N/A N=591 Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
Symptomatic Contact Lens Wearers
Primary: Likert Statement: When I Use This Solution, I Can Comfortably Wear my Lenses. — 3.9; 3.8 Units on a scale
N/A N=192 Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
Myopia · Hyperopia · Contact Lens Comfort
Primary: Subjective Lens Wear Comfort — 4.3; 4.3 units on a scale
N/A N=125 Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)
Healthy
Primary: Corneal Fluorescein Staining Type at Baseline — 1.7 Units on a scale
Phase 3 N=270 Evaluation of an Investigational Multi-Purpose Solution (MPS)
Study Focus is Healthy Contact Lens Wearers
Primary: Mean Lens Cleanliness as Measured by Light Reflectance — 65.5; 66.8 light reflectance score
N/A N=175 Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
Refractive Error
Primary: Mean Change From Baseline (Day 0) in Average Corneal Staining Area at Day 30 — -5.04 Percentage of corneal staining
N/A N=350 Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution
Adverse Effect of Contact Lens Solution
Primary: Subjective Assessment of Comfort and Cleanliness — 89.71; 89.26; 87.45; 86.63 Scores on a scale
N/A N=372 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
Refractive Error · Myopia · Hyperopia
Primary: Likert Scale Questionnaire Item: "I Can Comfortably Wear my Lenses" — 4.2; 4.4 units on a scale
N/A N=312 A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution
Ocular Discomfort
Primary: Comfort-related Symptoms/Complaints — 89.0; 88.3; 81.7; 81.9 Units on a scale
N/A N=22 Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
Contact Lens Wear
Primary: Ex Vivo Contact Angle — 104.8; 104.9; 103.3 degrees
N/A N=134 Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
Refractive Error
Primary: Mean Change From Baseline in Investigator Rated Lid Papillae Maximum Score at Day 90 — 2.3; 2.3; 2.2; 2.2 units on a scale
N/A N=441 Evaluation of Two Daily Disposable Contact Lenses.
Myopia
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 0; 0 eyes
Phase 2 N=30 Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
Myopia · Hyperopia · Astigmatism
Primary: Number of Eyes With No Change in Corneal Staining — 16; 17; 19; 14 eyes
N/A N=113 Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Primary: Subject Comfort — 92.4; 92.4; 92.0; 63.0 Units on a scale
N/A N=121 CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
Presbyopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score at Day 30 — 12.6; 14.8 units on a scale — p==0.0073
N/A N=36 Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
Refractive Errors
Primary: Average Percent Area of Corneal Staining — 2.93; 0.45; 6.06; 3.52 percentage of area
N/A N=106 Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
Myopia · Astigmatism · Hyperopia
Primary: Percentage of Subjects With Visibly Clean Lenses — 42.0; 57.1; 29.0; 42.9 percentage of subjects
N/A N=252 A Safety and Effectiveness Study of BL-ABT12 Multi-Purpose Solution for Use by Participants With Soft Contact Lenses
Contact Lens Wear
Primary: Overall Comfort — 88.9; 87.5 score on a scale
N/A N=446 Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
Myopia
Primary: Average Daily Wear Time — 13.57; 13.30 Hours
N/A N=42 Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Normal Contact Lens Wearers
Primary: Corneal Staining — 184; 46.6; 77.8 units on a scale