Phase 2 N=323 Provoked Craving Assessment
Smoking Dependence · Smoking
Primary: Change From Post-cue Baseline in Nicotine Craving Score at 5 Minutes — -41.8; -25.9 Score on a scale — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=19 The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Decreasing Food Cravings
Craving
Primary: Food Cravings — -26.81; -7.8 percentage of change in cravings
N/A N=29 Olfactory Contributions to Sleep-dependent Food Craving
Sleep Deprivation
Primary: Functional Magnetic Resonance Imaging (fMRI)-Based Decoding Accuracy of Food vs Non-food Odors in Piriform Cortex — 54.38; 49.65 Percentage correctly classified — p=0.001
Phase 3 N=322 Nicotine Mouth Film for Craving Relief.
Smoking Cessation
Primary: The Change From Pre-dose Post-provocation in Craving Score at 50 Seconds — -14.15; -9.26 mm — p=0.0141
Phase 2 N=120 Provoked Craving Relief Study by NRT
Smoking Cessation
Primary: Mean Change From Baseline in Nicotine Craving Score on a VAS — -11.3; -1.7; -4.6; -28.2 Score on a scale
Phase 2 N=187 Evaluation of the Nicotine Lozenge in Relief of Provoked Acute Craving
Smoking · Smoking Cessation
Primary: Mean Change From Baseline in Nicotine Cravings VAS Scores in Light Smokers — -15.40; -8.17; -24.42; -17.26 Score on a scale — p=0.0643
Phase 2 N=80 Sweet Preference and Alcohol Craving
Alcohol Dependence · Alcohol Abuse
Primary: Percent Heavy Drinking Days — 0.63; 0.14; 0.09; 0.17 percentage of days
Phase 1 N=10 Effect of Allopregnanolone on Stress-induced Craving
Alcohol Use Disorder
Primary: Alcohol Urge Questionnaire (AUQ) Pre-script — 24.45; 21.51; 19.15; 26.29 units on a scale
Phase 1 N=96 GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight
Obesity
Primary: Change in Craving Score — -0.7; -0.3 score — p=< 0.001
Phase 2 N=47 Craving and Lifestyle Management Through Mindfulness Study
Obesity
Primary: Change in Abdominal Fat — 68.2; 50.0 grams
N/A N=19 Transcranial Magnetic Stimulation Effects on Nicotine Craving
Nicotine Dependence
Primary: the Change From Baseline in Cue Nicotine Craving Rating Score — 64; 46 score on a scale
Phase 2 N=34 Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics
Alcoholism
Primary: Alcohol Craving Rating in Response to Saline Infusion — 1.704; 1.766 Units on a scale
N/A N=38 Effect of Snacks on Appetite Control
Healthy Canadians · Appetite Control
Primary: Total Area Under the Curve (AUC) for Hunger, Fullness, Desire to Eat and Prospective Consumption Using Visual Analog Scales (VAS) — 651; 1008; 638; 640 cm x min — p=<0.05
N/A N=45 Effects of Ghrelin on Alcohol Cue Reactivity and Craving
Alcoholism
Primary: Alcohol Visual Analogue Scale (A-VAS) — 1.95; 2.66; 4.29 units on a scale
N/A N=21 Protein Quality on Appetite Control, Reward-driven Eating, & Subsequent Food Intake
Appetite and General Nutritional Disorders
Primary: Eating Initiation — 250; 270; 245; 250 minutes
Phase 2 N=26 Effects of Aripiprazole on Cocaine Craving and Self-Administration
Cocaine Abuse
Primary: Cocaine Self-administration — 0; 1.5; 3; 4 Number of Choices
Phase 2 N=53 Effect of LY686017 on Alcohol Craving
Alcohol Dependence · Alcoholism
Primary: Craving for Alcohol (Spontaneous) — 19.7; 19.1 Units on a scale
Phase 4 N=32 Minocycline and Tobacco Craving in Smokers With Schizophrenia
Schizophrenia · Tobacco Use
Primary: Questionnaire for Smoking Urges-Brief — 42.1429; 38.6429; 43.4286; 36.8571 score on a scale
Phase 2 N=42 Acute and Short-term Effects of CBD on Cue-induced Craving in Drug-abstinent Heroin-dependent Humans
Opiate Addiction
Primary: Changes in Cue-Induced In-Clinic Craving (From Baseline to Post-cue (30 Minutes), and From Test Day 1 Through Test Day 4 (1 Week)) - Via the Visual Analog Scale for…
Phase 2 N=21 A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent Smokers
Nicotine Dependence
Primary: Change in Craving for Cigarettes After Smoking Cues Versus Neutral Cues Using a Repeated Measure Design. — -.18; .12; 1.29 units on a scale — p=0.014
N/A N=104 Sweet Consumption and Subsequent Sweet Food Preferences and Intakes
Dietary Behaviour
Primary: Sweet Food Preferences — 66; 63; 68 score on a scale
Phase 2 N=10 Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Humans
Opiate Addiction
Primary: Changes in Cue-Induced In-Clinic Craving (From Baseline to Post-cue or Post-neutral - Via the Visual Analog Scale for Craving (VASC) — 2.67; 0.83; -0.33; -0.17 units on…
N/A N=14 Aim 1: App for Reducing Cravings to Smoke
Smoking
Primary: System Usability Scale (Aim 1) — 70.3 score on a scale
Phase 1 N=20 Oxytocin, Stress, Craving, Opioid Use Disorder
Opioid Use Disorder
Primary: Opioid Craving — 21.6; 22.4; 23.3; 23.4 score on a scale
N/A N=36 Repeated Sweet Consumption and Subsequent Sweet Food Preferences and Intake
Repeated Sweet Food Consumption
Primary: Food Preferences — 7; 1 units on a scale
Phase 3 N=99 Aripiprazole Effects on Alcohol Drinking and Craving
Alcohol Dependence
Primary: Total Number of Drinks Per Day During Natural (Usual Environment) Conditions — 5.8; 6.4 standard drinks
N/A N=56 Medicinal Nicotine for Preventing Cue Induced Craving
Tobacco Use Disorder
Primary: Craving Symptom Severity Score Assessed Via Questionnaire — 0.52; 0.57; 0.31 units on a scale — p=0.25
N/A N=40 Cognitive Interference Task on Alcohol Craving and Consumption
Alcohol Drinking · Craving
Primary: Alcohol Craving — 2.51; 2.79 units on a scale
N/A N=30 Effect of Managing Problematic Eating Behaviours With Dietary Management on Chronic Disease Self-management
Hypertension · Type 2 Diabetes
Primary: The Change in EEQ (Emotional Eater Questionnaire) Score is the Primary Outcome Measure in This Study. — -1.7; -3.2 Scores on a scale
Phase 2 N=17 Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers
fMRI · Alcohol Drinking · Alcoholism
Primary: Alcohol Infusions Self-administered — 10.45; 8.80 Number of alcohol infusions