Phase 4 N=4 Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
Anesthesia, Local
Primary: Ropivacaine Concentrations — 0; 0; 1232.25; 850.25 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=12 Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
Distribution of Ropivacaine in Erector Spinae Plane Block
Primary: Area of Dermatomal Sensory Loss at 20 Min — 68.8; 167.5 cm^2
Phase 2 N=70 Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Erector Spinae Plane Block · Pain Control · Post-Operative Pain, Chronic
Primary: Quantitate the Amount of Opioid Medication Required to Provide Pain Relief-Cumulative First 48 Hours — 80.2; 54.9 Morphine Milligram Equivalents
Phase 4 N=33 Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery
Thoracic Surgical Procedures
Primary: Total Opioid Consumption — 187.36; 164.70 mg morphine equivalent (MME)
N/A N=93 Transversus Abdominis Plane Block Versus Erector Spinae Plane Block
Postoperative Pain · Laparotomy
Primary: Time of First Post Operative Analgesic Request — 14.9; 6.5; 2.8 Hour
Phase 4 N=46 Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery
Opioid Use · Pain, Postoperative
Primary: Intraoperative and Postoperative Opioid Consumption — 191; 139.4 MME/day
Phase 4 N=100 Erector Spinae Versus Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Numeric Rating Scale Pain Scores — 3.0; 0 score on a scale — p=0.0011
Phase 4 N=120 Transverse Abdominis Plane (TAP) Block After Cesarean Delivery
Postoperative Pain · Pregnancy · Obesity
Primary: Morphine Equivalents 0-24 Hours (Mgs) — 54; 38; 32; 45 Morphine equivalents (mg) — p=.05
Phase 2 N=5 Erector Spinae Plane Block for Uncomplicated Renal Colic
Renal Colic · Kidney Stone
Primary: Participants Who Received a Second Parenteral Pain Medication in the Emergency Department (ED) — 0 Participants
Phase 4 N=150 ESP Block for Post Cesarean Analgesia
Cesarean Section Complications
Primary: Postoperative Oxycodone Consumption 0- 48 Hours After Cesarean Delivery — 12.5; 25 mg
Phase 3 N=120 Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures
Pain, Postoperative · Thoracic · Acute Pain
Primary: The Primary Endpoint of This Study Will be 24 Hours VAS Pain Score at Rest — 4.1; 4.3; 3.3 score on a scale
N/A N=24 Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
Pain, Postoperative · Opioid Use · Recruitment
Primary: Number of Patients Who Receive Bilateral, Pre-incision ESPB — 9; 12 Participants
N/A N=39 Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Paresis
Primary: Forced Expiratory Volume at 1 Second (% Change From Baseline) — -22.4; -29.4 percentage of change from baseline
N/A N=71 Single Shot Lumbar Erector Spinae Plane (ESP) Block in Total Hip Replacement (THR)
Total Hip Replacement · Analgesia
Primary: Post-operative Pain Score in Numeric Rating Scale (NRS) From 0 (no Pain) to 10 (Extreme Pain) — 3; 3 score on a scale
Phase 3 N=60 Efficacy of TAP Block in Cesarean Section Patients
Pain Control
Primary: Effect of Transversus Abdominis Plane (TAP) Block Using Either 0.5% or 0.25% Bupivacaine on Analgesia for Cesarean Section Patients When Compared to Placebo. — 9.45…
N/A N=514 Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine
Pain, Postoperative · Major Abdominal Surgery
Primary: VRS Pain Score — 4.3; 4.2 score on a scale — p=<0.001
N/A N=30 A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Total Hip Arthroplasty · Postoperative Pain
Primary: Opiate Consumption Postoperatively — 8.21; 8.02 mg
N/A N=16 Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy
Anesthesia, Conduction
Primary: Skin Temperature Increase From Baseline — 1.9; 2.3 degrees C
N/A N=65 Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
Pain, Postoperative
Primary: Postoperative Pain (Pain Scores) Intensity Measure — 1; 3 units on a scale — p=0.001
N/A N=84 Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients
Pain, Postoperative
Primary: Opioids Consumption Via PCA — 107.29; 100.17 ng/kg/min
N/A N=20 Comparing Post-operative Analgesia After (PECS II) Block and (ESPB) in Modified Radical Mastectomy
Anaesthesia
Primary: Post-operative Pain Severity Assessed by Visual Analogue Scale Immediately Postoperative on Admission to the Post Anesthesia Care Unit. — 0.4; 0.9 score on a scale
Phase 3 N=211 Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block
Axillary Nerve Block
Primary: Percentage of Participants With Successful Block for Distal Upper Limb Surgeries — 96; 97 Participants
Phase 4 N=51 Efficacy of Continuous Infusion Ropivacaine Interscalene Blocks
Full-thickness Rotator Cuff Tear
Primary: Mean Visual Analog Scale — 3.5; 5.9; 3.1; 5.2 units on a scale — p=.006
Phase 4 N=45 Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
Postoperative Pain
Primary: Analgesic Requirement — 0.60 (mg/kg)
Phase 3 N=10 Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study
Pain, Postoperative
Primary: Number of Participants Who Completed a Successful Intervention With No Major Adverse Events — 10 Participants
Phase 4 N=15 Pharmacokinetics of Single-Dose Liposomal Bupivacaine in Surgeon Performed Intercostal Nerve Blocks
Thoracic
Primary: Tmax, or the Time Until the Maximum Concentration — 24 Hours
Phase 4 N=100 Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Mean/Median Numeric Rating Scale Pain Score Within the Recovery Room — 4; 0 score on a scale — p=0.001
N/A N=50 Pulmonary Function and Interscalene Block
Shoulder Arthroscopy
Primary: Number of Patients With Paradoxical Diaphragmatic Movement — 16; 8 Participants
N/A N=100 Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks
Pregnancy
Primary: The Time After the TAP Block When Rescue Analgesia Was First Sought — 13.12; 18.21 Hours
N/A N=80 Supraclavicular Brachial Plexus Block Using Ropivacaine Alone and With Dexmedetomidine
Brachial Plexus Anesthesia
Primary: Duration of Analgesia — 413.73; 197.35 minutes