Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=14 Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Blood Volume Analysis
Primary: Change in Total Blood Volume — 487 ml
N/A N=214 Hypotension Prediction Index for Blood Pressure Management
Intraoperative Hypotension
Primary: Time- Weighted Average (TWA) MAP Under a Threshold of 65 mmHg. — 0.14; 0.14 mmHg — p=0.757
N/A N=17,463 Decision Support for Intraoperative Low Blood Pressure
Hypotension
Primary: Postoperative Acute Kidney Injury — 1333; 372; 9670; 2785 Participants
N/A N=35 The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty
Anesthesia
Primary: The Hemoglobin (in g/dl) Levels — 12.2; 12.0; 11.9; 11.8 g/dl
Phase 4 N=3,626 Norepinephrine vs Phenylephrine During General Anesthesia
Anesthesia · Surgery · Hypotension
Primary: Number of Participants With Assigned Vasopressor Given — 1570; 1627 Participants
Phase 2 N=66 The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Hypotension · Pain
Primary: Changes Between the 3 Groups Assessed by Blood Pressure Measurement — 5; 2; 3; 10 Participants — p=0.165
N/A N=63 Intraoperative Ocular Pressure in Lumbar Spine Fusion Patients
Raised Ocular Pressure
Primary: Change in Intraoperative Ocular Pressure in Lumbar Spine Fusion Patients Head Raised 10 Degrees or Kept in Neutral Position — 9.26; 13.79 mm Hg
N/A N=429 Predict Fluid Responsiveness in Spinal Anesthesia
Hypotension and Shock · Excessive Amount of Blood / Fluid Infusion
Primary: Percentage of Participants With Systemic Hypotensions — 68; 46; 65 Participants
Phase 4 N=82 Spinal Anesthesia Induced Hypotension During Cesarean Section
Hypotension
Primary: Incidence of Maternal Hypotension — 10.8; 27 percentage of participants
N/A N=100 Cerebral Oxygenation in Total Hip Arthroplasty Patients
Cerebral Oxygen Desaturation · Post-operative Delirium
Primary: Oxygen Desaturation Incidences — 4 Participants
Phase 4 N=291 Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Hypotension on Induction
Primary: Number of Participants With Interoperative Hypotension — 76; 95 Participants — p=0.03
Phase 4 N=178 Preventing Hypotension in Parturients With an Elevated Body Mass Index (BMI)
Hypotension
Primary: Incidence of Nausea and Vomiting — 59; 37 participants
N/A N=67 The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-Assisted Laparoscopic Radical Prostatectomy
Primary: Maximum Intraocular Pressure During RALRP Under Deep Neuromuscular Blockade — 23.3; 19.8 mmHg
N/A N=51 Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Hypotension · Anesthesia
Primary: Number of Participants Who Had Hypotensive Events — 8; 21 Participants — p=0.01
Phase 4 N=80 Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Anesthetic Complication Spinal
Primary: Number of Physician Interventions Needed to Maintain Maternal Blood Pressure After Spinal Anesthesia Within 20% of Baseline and to Treat Bradycardia During Cesarean…
N/A N=34 Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
Anesthesia, Epidural · Hypotension
Primary: Time-to-treatment of Hypotension (Minutes) — 21.8; 23.1 minutes
N/A N=160 Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Fluid Overload · Anesthesia; Adverse Effect, Spinal and Epidural · Regional Anesthesia Morbidity
Primary: Rate of Arterial Hypotension — 42.5; 27.5 percentage of participants
Phase 4 N=115 Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
Hypotension During Surgery · Blood Loss, Surgical
Primary: Surgeon's Analysis of Surgical Field Visualization — 1.3 score on a scale
N/A N=30 Cerebral Blood Flow During Propofol Anaesthesia
Gastrointestinal Neoplasms
Primary: Changes in Internal Carotid Artery Blood Flow by Treatment of Anaesthesia-induced Hypotension — 27 ml/min — p=0.0276
Phase 3 N=72 Postoperative Consequences of Intraoperative NOL Titration
Anesthesia; Adverse Effect
Primary: Pain Scores at 10-minute Intervals for the Initial Hour of Recovery — 0; 0; 1.0; 5.0 score on a scale — p=0.895
N/A N=65 Does Heart Rate Variablity (HRV) Predict Hypotension in Patients Undergoing Cervical Myelopathy Surgery ?
Heart Rate Variability
Primary: Heart Rate Variability (HRV) — 1439; 2191 ms2
Phase 3 N=100 Does High Intraoperative Inspired Oxygen Reduce Postoperative Arterial Oxygen Saturation?
Atelectasis
Primary: Oxygen Requirement to Maintain SpO2>90% — 1; 1; 1; 1 liters per minute
N/A N=110 Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Preeclampsia · Hypotension
Primary: The Umbilical Artery pH — 7.22; 7.20 pH — p=.38
Phase 3 N=59 Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
Anesthesia
Primary: Change in Base Deficit — -1.5; -1.2; -0.5 mEq/L
N/A N=68 Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
Intracranial Aneurysm · Brain Edema · Scoliosis
Primary: Number of ICU Stays Greater Than 1.5 Days — 13; 20 Number of ICU Stays greater that 1.5 Day
Phase 3 N=20 Intraoperative Lidocaine Infusion for Postoperative Pain Management in Obese Patients
Bariatric Surgical Pain
Primary: Postoperative Pain — 3; 4.5; 8; 8 units on a scale
Phase 4 N=70 Pilot - Peri-operative Beta Blockade
Adrenergic Beta-Receptor Blockader · Troponin Levels · Cardiomyopathy, Post-surgical
Primary: Difference in hscTnI Values — 3.4; 2.8 ng/L
N/A N=42 Intraoperative Warming Comparison of Devices
Hypothermia
Primary: Percent of Patients With an Average Intraoperative Temperature Greater Than or Equal to 36 Celcius — 56; 90 percentage of participants — p=0.027
N/A N=200 Perioperative Blood Pressures and Chronic Hypertension
Hypertension
Primary: Performance of Blood Pressure Referral Threshold — .841 proportion