N/A N=43 Do Terpenes Play a Role in the Stress-reducing Effects of a Forest Bathing Intervention?
Monoterpene Exposure During a Forest Bathing Intervention
Primary: Changes in the HF (ms^2) Component of HRV — 6.65; 6.48 ms^2 — p=0.914
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=24 Evaluation of Post-Exposure Sauna Treatment of Firefighters - A Pilot Study
Post-fire Rehabilitation of Firefighters in Sauna
Primary: Urinary Excretion of Hydroxylated PAHs (PAH-OHs) — 10364.2; 40012.1; 6964.1; 22604.3 ng/L — p=0.0000009
N/A N=47 Affective Responses in Mountain Hiking
Affect
Primary: Change From Baseline Subscales of Mood Survey Scale at 3 Hours — 0.54; -1.27; -2.22 score on a scale
N/A N=100 Using Aromatherapy in Substance Use Disorder
Substance Use Disorders
Primary: Examine Feasibility (Eligible Participant Recruitment) — 45; 55 Participants
N/A N=77 Reducing Traffic Pollution Exposure Improves Blood Pressure
Air Pollution
Primary: Systolic Blood Pressure (SBP) — 122.3; 120.83; 119.9 mmHg
Phase 1 N=33 Behavioral Pharmacology of THC and Alpha-pinene
THC · Alpha-pinene
Primary: Mean Peak Change From Baseline Drug Effect as Assessed by the Drug Effect Questionnaire (DEQ) — -1.2; 5.1; 67.2; 66.1 score on a scale
N/A N=35 Intervention Study on the Health Impact of Air Filters in Chinese Adults
Inflammation · Coagulation · Blood Pressure
Primary: Circulating Biomarkers — 926.3; 913.1; 1122.2; 1108.2 ng/ml
N/A N=60 Health Effects of Indoor Air Filtration in Healthy Chinese Adults
Blood Pressure
Primary: Changes of Serum Cortisol Levels — 0.012835; 0.016206 relative intensity — p=<0.05
N/A N=9 Woodsmoke Particulate + Hypertonic Saline
Airway Inflammation
Primary: Change From Baseline to 4 Hours in Sputum Percent Neutrophils — -0.04; -0.5 percent neutrophils — p=> 0.99
Phase 2 N=16 A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults
Airway Inflammation · Asthma
Primary: Change in Sputum % Polymorphonuclear Neutrophils (PMN) With Wood Smoke Particulate (WSP) Exposure — 18.00; 14.75 percent PMNs — p=0.67
N/A N=160 Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
Smoking
Primary: Concentration of Monohydroxybutenyl Mercapturic Acid (MHBMA) — 83.21; 617.04; 83.57 pg/mg creat — p=<.001
N/A N=28 Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
Autonomic Nervous System Imbalance · Blood Pressure · Inflammation
Primary: Heart Rate Variability-LF Power,HF Power,VLF Power — 899.4; 838.5; 519.7; 416.6 ms^2 — p=<0.05
Phase 1 N=35 Behavioral Pharmacology of THC and D-limonene
D-limonene and THC Pharmacodynamics
Primary: Mean Peak Change From Baseline Anxiety as Assessed by the Drug Effect Questionnaire (DEQ) — -1.2; 13.8; 18.7; -1.9 score on a scale
Phase 2 N=18 Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure
Allergic Asthma
Primary: Change From Baseline in Sputum Percent Neutrophils (%PMN) Following Ozone Exposure — 34.1; 36.5 percent neutrophils
N/A N=160 Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Smoking
Primary: Concentration of Monohydroxybutenylmercapturic Acid (MHBMA) — 110.96; 882.25; 94.97 pg/mg creat — p=<0.001
N/A N=66 Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
Hypertension
Primary: Memory Function — 25.5; 24.0; 9.7; 9.0 score on a scale
N/A N=434 Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age
Endocrine Disrupting Chemicals · Environmental Exposure · Health Literacy
Primary: Changes in Endocrine Disrupting Chemical (EDC) Levels as Measured by the Post-intervention Value Minus the Baseline Value. — 5.83; 18.43; 56.94; 75.30 ng/ml — p=<0.05
N/A N=94 Aromatherapy for Management of Pain, Anxiety, and Nausea in the Acute Care Setting
Effectiveness of Aromatherapy
Primary: Numerical Rating Pain Scale — 5.7; 5.3; -1 score on a scale — p=0.008
Phase 2 N=70 Intraoperative Aromatherapy Versus Placebo for Port-a-Cath Placement Under Monitored Anesthesia Care. A Randomized Controlled Trial
Cancer Pain
Primary: To Compare the Time to Readiness for Discharge From PACU (Minutes) After Port-a-Cath Placement Surgery Between Patients Who Are Randomized to Receive Intraoperative…
N/A N=24 The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors
Loneliness · Social Isolation · Mood
Primary: Loneliness (Time 1) — 4.08; 5; 3; 3 units on a scale
Phase 1 N=40 Feasibility of Aromatherapy in an Awake Craniotomy Environment
Intracranial Pathology
Primary: Number of Consented Patients — 40 Participants
Phase 2 N=170 Broccoli Sprout Dose Response: Bioavailability and Effects of Air Pollutants
Environmental Carcinogenesis
Primary: Sulforaphane Bioavailability Measured in Sequential 12-Hour Urine Samples — 24.8; 11.0; 4.3 micromoles/24 hours — p=<0.001
N/A N=68 Effects of Lentinula Edodes Bars on Dyslipidemia and Oxidative Stress in Cholesterol Individuals: Randomized Study
Dyslipidemias
Primary: Total Cholesterol Levels — 222.8; 228.2; 226.7; 229.6 mg/dL — p=0.59
Phase 3 N=38 The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels
Neonatal Abstinence Syndrome · Aromatherapy
Primary: Length of Hospitalization — 17.8; 11.4 days — p=0.03
Phase 2 N=92 Use of Aromatherapy to Reduce Symptom Burden
Anxiety · Chemotherapy-induced Nausea and Vomiting
Primary: Chemotherapy-induced Nausea, Vomiting, and Retching (CINVR) Symptoms at Baseline, 25 Hours, and 48 Hours — 9.6; 8.5; 5.2; 4.9 score on a scale — p=0.462
Phase 4 N=12 The Influence of Menthol Gel During Exercise With Heat
Acute Exercise · Heat Exposure
Primary: Skin Blood Flow — 131.6; 119.2 arbitrary units — p=0.742
N/A N=35 Characterization of Selected Aerosol Constituents Levels in the Exhaled Breath of Adult e-Vapor Users
Tobacco Use
Primary: Nicotine Residue Summary Statistics by Test-Product Group — 87.1; 192.3; 174.1; 182.8 Micrograms
N/A N=46 Cleaner Air for Better Cardiac Biomarkers
Cardiovascular Diseases
Primary: Percent Change in Circulating Concentration of Tumor Necrosis Factor Alpha (TNFα) — -1.03; 2 percent change
Phase 2 N=413 University of Wisconsin Meditation & Exercise Cold Study
Acute Respiratory Infection
Primary: Severity-weighted Total Days of ARI Illness — 1045; 1010; 1210 severity*days
N/A N=144 Effects of Aromatherapy on Patient Satisfaction With Surgical Abortion at Less Than 10 Weeks Gestation
Surgical Abortion · Patient Satisfaction · Anesthesia
Primary: Patient Satisfaction With Anesthesia — 0.72; 0.46 score on a scale