N/A N=266,499 Polypharmacy and Outcomes After Elective Noncardiac Surgery
Polypharmacy · Surgical Procedure, Operative · Morality
Primary: Mortality — 4356; 1919 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=164 Extracardiac Complications After Cardiac Surgery
Acute Lung Injury · Sepsis · Infections
Primary: Acute Lung Injury After Cardiac Surgery — 20 participants — p=<0.05
N/A N=266,499 The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery
SURGICAL PROCEDURES, OPERATIVE · Aged · Epidemiology
Primary: Number of Participants With All-Cause Mortality at 90-days — 103; 6172 Participants
N/A N=244,976 Anticholinergic Risk Scale and Resource Use After Elective Noncardiac Surgery
Length of Stay · Anti Cholinergics · Surgical Procedure, Operative
Primary: Hospital Length of Stay — 6.8; 7.8; 7.5 Days
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=1,439 Epidemiology of Severe Peroperative Bleeding During Scheduled Surgery
Surgery · Blood Loss
Primary: Unanticipated Bleeding — 0; 100; 0 percentage of participants
Phase 3 N=600 Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery
Elevated Cardiac Risk · Coronary Arteries Disease Risk
Primary: Number of Participants With Myocardial Necrosis (MN) — 57; 54 participants — p=0.0052
Phase 4 N=7,112 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial
Coronary Artery Disease
Primary: The Primary Endpoint is a Composite of Death and Cardiovascular Events (Clinical and Silent MI, Cardiac Failure, Cardiac Arrest, Pulmonary Embolism, and Stroke) Measured…
N/A N=460 Cerebral Autoregulation Monitoring During Cardiac Surgery
Thoracic Surgery · Cardiopulmonary Bypass
Primary: Composite Neurological Outcome of Clinical Stroke or New Ischemic Brain Lesion on Diffusion Weighted MRI or Neurocognitive Dysfunction 4 to 6 Weeks After Surgery. — 79…
Phase 4 N=70 Pilot - Peri-operative Beta Blockade
Adrenergic Beta-Receptor Blockader · Troponin Levels · Cardiomyopathy, Post-surgical
Primary: Difference in hscTnI Values — 3.4; 2.8 ng/L
N/A N=297 Natriuretic Peptides - Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?
Surgery
Primary: Occurence of Adverse Cardiac Events — 91 participants
N/A N=75 VItamin D Metabolism in SEnescent Cardiac Surgery Patients
Coronary Artery Bypass Grafting · Heart Valve Surgery
Primary: Peri- and Postoperative Time Course of Circulating 1,25-dihydroxyvitamin D in the First Postoperative Month in Cardiac Surgery Patients — 13; 4.2 percentage
N/A N=483 Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery
Acute Coronary Syndrome · Coronary Stent Occlusion · Surgery
Primary: Major Adverse Cardiac and Cerebrovascular Events (MACCEs) — 63 participants
N/A N=4,021 South African Surgical Outcomes Study
Mortality Following Noncardiac Surgery
Primary: Mortality — 123 participants
N/A N=1,113 Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury
Acute Kidney Injury
Primary: Mortality — 96; 34 Participants — p=<0.0001
N/A N=47 Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post Operative Cognitive Dysfunction
Primary: Presence of Post Operative Cognitive Dysfunction (POCD) — 15 Participants
Phase 3 N=10,010 PeriOperative ISchemic Evaluation-2 Trial
Cardiovascular Disease
Primary: Composite of All-cause Mortality and Nonfatal MI — 173; 194; 178; 161 participants
N/A N=5,056 Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
Perioperative Care · Surgery--Complications · Hypothermia; Anesthesia
Primary: Number of Participants With a Composite Outcome Consisted of Myocardial Injury After Non-cardiac Surgery (MINS), Non-fatal Cardiac Arrest, and All-cause Mortality — 239…
Phase 4 N=647 Multicenter Infection Surveillance Study Following Open Heart Surgery
Surgery · Pneumonia · Surgical Site Infection
Primary: Hospital Acquired Pneumonia — 8; 18 participants
Phase 4 N=3,626 Norepinephrine vs Phenylephrine During General Anesthesia
Anesthesia · Surgery · Hypotension
Primary: Number of Participants With Assigned Vasopressor Given — 1570; 1627 Participants
Phase 4 N=130 Prevention of Atrial Fibrillation Following Noncardiac Thoracic Surgery
Atrial Fibrillation
Primary: Incidence of Atrial Fibrillation Requiring Treatment — 9; 21 participants — p=0.02
Phase 4 N=285 Dexmedetomidine and Delirium in Patients After Cardiac Surgery
Delirium · C.Surgical Procedure; Cardiac · Postoperative Complications
Primary: Incidence of Postoperative Delirium — 7; 11 Participants — p=0.341
N/A N=168 Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
Post-Resuscitation Syndrome · Critical Illness · Cardiac Arrest
Primary: 30-Day Mortality — 112 participants
Phase 4 N=60 Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
Delirium
Primary: The Incidence of Delirium (Number of Patients (in Digits)) — 1; 2 participants
Phase 4 N=121 Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery
Delirium
Primary: Incidence of Delirium — 2; 4; 8; 9 Participants
N/A N=100 Delirium and EuroSCORE II in Cardiac Surgery
Delirium
Primary: Number of Participants With Delirium — 5 Participants
Phase 4 N=291 Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Hypotension on Induction
Primary: Number of Participants With Interoperative Hypotension — 76; 95 Participants — p=0.03
Phase 4 N=100 Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery
Neuromuscular Blockade · Postoperative Complications
Primary: Number of Participants With Postoperative Pulmonary Complications — 8; 8 Participants — p=1.00
Phase 3 N=201 Risk of Oxygen During Cardiac Surgery Trial
Cardiac Surgery
Primary: Intraoperative Systemic Oxidative Damage — 69; 83 pg/ml
N/A N=200 Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
Coronary Artery Disease · Postoperative Cognitive Dysfunction · Neurological Impairment
Primary: Difference in Incidence of Cognitive Impairment Between Groups. Change Between Preoperative and Postoperative Cognitive Function Was Assessed by Performing Standardized…