Phase 3 N=583 Negative Pressure Wound Therapy in Post-Operative Incision Management
Negative-Pressure Wound Therapy
Primary: Number of Post-op Wound Complications — 2; 5; 42; 36 Wound Complications
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=164 Negative Pressure Wound Therapy to Reduce Surgical Site Infection
Patients Undergoing Hepatopancreatobiliary Surgery
Primary: Participants With a Surgical Site Infection — 14; 20 Participants — p=0.27
N/A N=160 Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
Prosthesis-related Infections · Wound Complications · Joint Diseases
Primary: Number of Patients With Wound Complications — 9; 22 participants
N/A N=441 Negative Pressure Wound Therapy in Cesarean Section
Postoperative Wound Complications
Primary: Number of Participants With Wound Complication — 37; 42 Participants — p=0.54
N/A N=150 Negative Pressure Wound Therapy as a Drug Delivery System
Diabetic Foot Ulcers
Primary: Number of Participants Who Achieved Complete Healing or Coverage of the Study Wound — 44; 45 Participants — p=0.87
Phase 1 N=41 Simplified Negative Pressure Wound Therapy
Wounds
Primary: Maintenance of Negative Pressure — 22.2 hours
N/A N=20 Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Surgical Wound
Primary: Progression of Wound Healing — 69.9; 75.6 percentage of skin graft take
N/A N=1,869 Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
Surgical Wound Infection
Primary: Wound Infection After Open Heart Surgery — 4; 17 Participants — p=0.55
N/A N=30 Procellera and Negative Pressure Therapy for Acute Wounds
Wound
Primary: Wound Infection — 13; 12 participants
N/A N=164 Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)
Venous Leg Ulcers · Diabetic Foot Ulcers
Primary: Change in Ulcer Area From Baseline to the End of the Treatment Period — 6.2; 7.8; 0.7; 3.8 cm^2 — p=0.001
N/A N=160 Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds
Sarcoma · Cancer · Infectious Disease
Primary: Wound Complication Rate — 3.7; 3.7; 2.1; 2.2 score on a scale
N/A N=110 Negative Pressure Wound Therapy After Cesarean Delivery
Major Puerperal Infection, Postpartum · Wound Complications · Wound Seroma
Primary: Wound Complication Rate — 3; 1; 3; 6 participants
Phase 4 N=10 Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions
High Risk Abdominal Wounds
Primary: Number of Participants With Surgical Site Infections Within 1 Month (4 Weeks ) From Index Operation — 1 Participants
N/A N=81 Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients
Postoperative Complications · Obesity · Gynecologic Neoplasms
Primary: Number of Participants Who Experience Wound Complications (Wound Dehiscence or Infection) — 25; 33; 12; 9 Participants — p=0.27
N/A N=154 Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Section in High Risk Patients
High Risk Pregnancy · Cesarean Wound Disruption With Postnatal Complication
Primary: Wound Complication — 13; 14 Participants
N/A N=46 Prevention of Seroma Formation and Wound Complications Using NPWT Devices
Seroma · Wound Dehiscence · Wound Infection
Primary: Post-operative Seroma Formation — 16.9; 10.1 cm^3
N/A N=87 Comparison of Two Methods of Negative Pressure Wound Therapy
Acute Wounds From Trauma · Dehiscence or Surgical Complications
Primary: Percent Change Per Day in Wound Surface Area — -4.5; -4.9 % change per day — p=0.60
N/A N=132 SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds
Ulcers · Wounds
Primary: Percent Change in Wound Area — -85.7; -94 percentage of baseline wound area
N/A N=24 Negative Pressure Wound Therapy-PICO: Cosmesis in Repeat C-Sections
Hypertrophic Skin Condition of Anterior Abdomen
Primary: Subjective Cosmetic Result — 13; 26.5 units on a scale
N/A N=16 Evaluation of Negative Pressure Wound Therapy in the Treatment of DFUs Incl. Post Amputation Wounds.
Diabetes · Foot Ulcers
Primary: Mean Change in Wound Area. — -33.7 cm2
N/A N=43 Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
Open Wound Abdominal Wall · Wound Non Healing
Primary: Closure Rate of Non-healing Wounds — 45.79; 89.98 percentage of healing
N/A N=200 PICO Breast Reduction Clinical Study Looking at Incision Healing Complications
Delayed Healing
Primary: Number of Participants Experiencing Incision Healing Complications up to Day 21 Postoperatively — 113; 86; 123; 76 participants
Phase 4 N=100 Comparing Outcomes for Prontosan Versus Normal Saline for Negative Pressure Wound Therapy With Instillation
Wound Infection
Primary: Number of Operating Room Visits — 2.5; 2.8 Operative Room Visits
Phase 4 N=140 A Randomized Clinical Trial Evaluating Negative Pressure Therapy to Decrease Vascular Groin Incision Complications
Wound Infection · Peripheral Arterial Disease · Aneurysm
Primary: Groin Wound Complication — 6; 19; 1 Participants
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
N/A N=104 Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
N/A N=526 Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery
Wound of Knee · Wound of Hip
Primary: Incision Appearance Based on VAS (Incision Healing Assessment Form) — 83.4; 83.5 units on a scale
N/A N=120 Prophylactic Incisional Care in Obese Women at Cesarean
Wound Infections
Primary: Number of Participants With Composite Surgical Site Infection (SSI) or Other Wound Complication. — 5; 3 Participants — p=0.72
N/A N=124 Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Surgical Site Infection · Pancreatic Neoplasms · Pancreatic Cancer
Primary: Rate of Surgical Site Infection — 6; 19 Participants — p=0.003
N/A N=90 NPWT PRO vs KCI Ulta® NPWT and to Compare NPWT PRO vs NPWT PRO With Simultaneous Irrigation on Wound Healing
Partial-thickness Burn · Ulcer
Primary: Number of Participants Who Achieved Complete Wound Healing — 15; 19; 14 Participants