N/A N=57 Insulin-sensitive Obesity: Lessons From Longitudinal Data
Insulin Sensitivity/Resistance · Obesity
Primary: Insulin Sensitivity — 0.0105; -0.0076; 0.0041 micro mol/min/Kg/mU/L/year
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=47 Healthy Bodies, Healthy Kids
Child Mental Disorders · Obesity · Metabolic Syndrome
Primary: DEXA-measured Adiposity — 0.76; -0.43; -2.79 kilograms — p=0.01
N/A N=47 Antecedents of Obesity: Fetal Measures of Adiposity
Obesity
Primary: Infant Adiposity at 24-72 Hours Following Birth — 11 Percentage of total body weight
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
Phase 4 N=226 Obesity, Oral Contraception, and Ovarian Suppression
Ovarian Suppression
Primary: Risk of Oral Contraceptive (OC) Failure Due to Less Contraceptive-mediated Ovarian Suppression. — 54; 28; 11; 12 Participants
N/A N=60 Dysregulation of FSH in Obesity: Functional and Statistical Analysis
Obesity · Fertility
Primary: Difference Between Peak Inhibin B — 100.8; 38.8 picograms/mL
N/A N=5,392 Impact of Body Weight on the Immediate Health of the Pediatric Population
Childhood Obesity
Primary: Diagnosis of Infectious Disease — 900; 1067 Participants — p=.026
N/A N=80 Effects of Obesity Treatments on Food Preferences and Metabolism
Obesity · Type 2 Diabetes Mellitus
Primary: Change in Energy Intake From Baseline — 500; 310; 482; 5 kcal
N/A N=271 Weight Discrimination and Poor Cardiovascular Health
Obesity
Primary: Negative Affect — 1.43; 1.29 score on a scale — p=.007
N/A N=79 Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Weight Loss · Anovulation · Amenorrhea
Primary: Change From Baseline Ovulatory/Menstrual Function — 12; 18 Participants
N/A N=264 School Nurse-directed Secondary Obesity Prevention for Elementary School Children
Overweight · Obesity
Primary: Child Body Mass Index (BMI) — 1.6; 1.5; 1.7; 1.6 units on a scale
N/A N=50 Bariatric Surgery for Morbid Obesity
Obesity · Morbid Obesity
Primary: Size of Adipocytes — 73.4; 99.0; 103.0 µm
N/A N=30 Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
Obesity · Infertility
Primary: Luteinizing Hormone Pulse Amplitude — 2.73; 1.12 IU/L
N/A N=39 Early-onset Obesity and Cognitive Impairment in Children With Pseudohypoparathyroidism
Pseudohypoparathyroidism · Albright Hereditary Osteodystrophy
Primary: Intelligence Quotient — 85.9; 104.3; 103.2 units on a scale
N/A N=33 Young Adult Eating Habits
Eating Behavior · Eating Habit
Primary: Change in Brain Response From Baseline to 2-weeks Post High UPF or 2 Weeks no UPF Diet — 0.02; 0.13 arbitrary units
N/A N=28 Increased Monitoring of Physical Activity and Calories With Technology
Weight Change, Body · Behavior, Health · Obesity, Childhood
Primary: BMI Percentile — 98.46; 99.37 BMI percentile for age and sex
N/A N=65 Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Weight Gain · Healthy Subjects · Obesity
Primary: Proportion of n-6 HUFA in Total HUFA (%n-6 in HUFA) — 80.0; 81.3; 80.5 Percentage of total HUFA
Phase 2 N=272 A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities
Obesity · Overweight and Obesity
Primary: Percent Change From Baseline in Body Weight in LY3502970 and Placebo — -8.6; -11.2; -12.3; -12.6 Percent change — p=<0.001
N/A N=360 Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Maternal Obesity · Gestational Weight Gain · Obstetric Complications
Primary: Cesarean Section
N/A N=61 Healthy Weight for Teens
Obesity
Primary: Number of Participants With Successful Implemenmtation of BPE (Bundle of Program Enhancements) in Existing Multi-component PWM Programs — 20; 12 Participants
N/A N=102 Metformin in Overweight Type 2 Diabetes Mellitus
Obesity · Type 2 Diabetes Mellitus
Primary: Change in Weight From Baseline at 12 Months or More — -8.37 Kg — p=<0.05
Phase 2 N=33 Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Obesity · Weight Loss · Overweight and Obesity
Primary: Safety: The Incidence of Treatment-related Adverse Events [AEs] — 0; 0; 0; 0 participants
Phase 3 N=130 A Primary Care Behavioral Approach for Addressing Childhood Overweight
Obesity
Primary: BMI Z-score(for Gender and Age)at 6-months — -0.129; 0.001 Z-score
Phase 2 N=200 Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases
Diabetes Mellitus · Hypertension · Metabolic Disease
Primary: Change in BMI Standard Deviation Score — -0.12; -0.06 Standard Deviation Score — p=0.007
N/A N=2,060 The Louisiana (LA) Health Project
Childhood Obesity
Primary: % Body Fat (Boys) — -1.3; -2.0; -0.11 percentage of body fat
N/A N=50 Guided Self-help for Families With an Overweight Child
Obesity
Primary: Child BMI — 23.3; 25.17 kg/m^2
N/A N=436 Study of Gelesis100 on Body Weight in Overweight and Obese Subjects With and Without Type 2 Diabetes
Overweight · Obesity
Primary: Co-Primary Outcome: Percent Change in Body Weight — -6.41; -4.39 percentage change in body weight — p=0.0007
Phase 1 N=22 PED NEONAT 20-000599 Fetal Body Composition
IUGR · Gestational Diabetes · Pregnancy Related
Primary: Maternal Visceral Adipose Tissue Volume — 97593; 169626; 96787 mm3
N/A N=51 Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity
Primary: Total Myocardial Oxygen Consumption (MVO2) — 1064; 1202; 947; 835 µmol/min
N/A N=277 Toddler Overweight Prevention Study Among Low-Income Families
Overweight · Obesity · Depression
Primary: Change of Body Mass Index (BMI) Z-score for Toddlers — 0.49; 0.50; 0.62; 0.52 z-score — p=0.555