N/A N=110 Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Preeclampsia · Hypotension
Primary: The Umbilical Artery pH — 7.22; 7.20 pH — p=.38
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=40 Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Pregnant Women · Pain · Hypotension
Primary: Time to Regression of Motor Block — 180; 130 minutes
N/A N=4,577 Incidence of Obstructive Sleep Apnea in Pregnancy
Obstructive Sleep Apnea · Pregnancy
Primary: Positive Berlin Questionnaire Indicative of Sleep Disordered Breathing — 1343; 96 participants — p=0.001
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
Phase 4 N=91 Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine
Cesarean Section
Primary: Induction to Delivery Interval — 268; 276 seconds
N/A N=57 Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Pregnancy
Primary: Changes in Maternal Ventilation During Labor Analgesia — 15.3; 12.6; 13.8 L/min
N/A N=212 Intrapartum Maternal Oxygen Supplementation: Effects on the Mother and Neonate
Intrauterine Resuscitation
Primary: Umbilical Artery Malondialdehyde — 9.8; 10.2 umol/L
Phase 2 N=40 Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery
Pregnant Women
Primary: Success of Anesthesia — 4; 4; 4; 1 Participants
N/A N=280 Ultrasonography Versus Palpation for Spinal Anesthesia in Obese Parturients Undergoing Cesarean Delivery
Anesthesia, Spinal · Cesarean Section · Spinal Ultrasound
Primary: Number of Needle Passes Required to Obtain Free Cerebrospinal Fluid Flow — 3; 3 needle passes — p=0.62
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
N/A N=108 Obstructive Sleep Apnea in Pregnancy
Sleep Apnea, Obstructive · Pregnancy · Obesity, Morbid
Primary: Number of Participants With a Negative Obstructive Sleep Apnea (OSA) Home Sleep Test Result — 61 Participants
Phase 4 N=141 DPE Technique in Labor Epidural for Morbidly Obese Women
Morbid Obesity · Labor Pain
Primary: Number of Participants Who Required Asymmetric Block, Top-up Interventions, Catheter Adjustments, Replacement of Epidural Catheter, or Failure of Block Requiring…
N/A N=23 Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Infants Undergoing Surgery
Primary: Cerebral Non-invasive Near Infrared Spectroscopy (NIRS) — 0.05 percentage change per minute
N/A N=40 Pre-Oxygenation Techniques in Pregnancy
Preoxygenation
Primary: End Tidal Oxygen Concentration (ETO2) Following Tidal Volume Breathing Using Either Face Mask or OptiFlow — 91.0; 87.4 Percentage units of end-tidal oxygen
Phase 4 N=82 Spinal Anesthesia Induced Hypotension During Cesarean Section
Hypotension
Primary: Incidence of Maternal Hypotension — 10.8; 27 percentage of participants
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents
Phase 4 N=178 Preventing Hypotension in Parturients With an Elevated Body Mass Index (BMI)
Hypotension
Primary: Incidence of Nausea and Vomiting — 59; 37 participants
Early Phase 1 N=15 Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery
Cesarean Section
Primary: Chloroprocaine Plasma Concentration at 1 Minute — 14.3; 7.5; 3.5 ng/ml
N/A N=276 Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Primary: Incidence of New-onset Category II or III Fetal Heart Rate Tracings — 72; 52 Participants
Phase 4 N=42 ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
Obesity, Morbid · Spinal Anesthesia · Cesarean Delivery
Primary: Number of Participants With Successful Blocks for Induction (Success Induction) — 1; 3; 27; 11 Participants
N/A N=72 Positive Pressure at Induction of Anesthesia in Children
Continuous Positive Airway Pressure · Hypoxia · General Anesthesia
Primary: Time Between Onset of Apnea and the Drop in 95% Oxyhemoglobin Saturation Levels — 227.65; 133.68 seconds — p=<0.0001
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
Phase 3 N=45 Bupivacaine With Epidural Volume Extension
Spinal Anesthesia · Epidural; Anesthesia
Primary: Time Until PACU Discharge in Minutes — 135; 50 minutes
N/A N=18 Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40
Labor Pain
Primary: Total Time Required for Epidural Catheter Placement — 6.1; 11.0 Minutes
Phase 4 N=23 Anesthesia and Postoperative Pain
Postoperative Pain
Primary: Score on a Pain Rating Scale (Numerical Analog Score) — 1.5; 4.9 scores on a scale
N/A N=50 EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
Obesity, Morbid
Primary: Non Hypoxic Apnea Time — 216.7; 258.2 seconds — p=0.005
N/A N=140 Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
Pain Levels
Primary: Onset Time of Surgical Anesthesia — 422; 655 seconds
N/A N=40 Pre-warming Prevents Hypothermia in Elective Cesarean Section
Hypothermia
Primary: Maternal Hypothermia — 36.6; 36.4; 36.5; 36.3 Centigrades — p=<0.05
N/A N=150 Utility of Ultrasound in Identification of Midline and Placement of Epidural in Severely Obese Parturients
Epidural Anesthesia · Spinal Ultrasound · Obesity
Primary: Time for Epidural Placement — 9.0; 6.2 minutes
N/A N=30 Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients
Idiopathic Scoliosis
Primary: Amplitude Required to Elicit the MEP — 307; 417 milliamperes