N/A N=10 Cross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus
Nystagmus
Primary: Change in logMAR Visual Acuity of Each Eye, Measured During Far or Near Viewing — 0; 0.1; 0.2; 0.2 logMAR
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=78 Vestibular Testing: Consistency and Effects Over Time
Dizziness
Primary: Vestibular Reaction Times — 240.89; 202.96; 233.09; 228.95 msec
N/A N=10 Sensory Training for Visual Motion Sickness
Dizziness · Vertigo · Motion Sickness
Primary: Rod and Disk Test (RDT) Mean Performance — 17; 13.3; 7.8; 12.1 degrees
N/A N=23 Recovery of Visual Acuity in People With Vestibular Deficits
Vestibular Neuronitis · Vestibular Neuronitis, Bilateral · Vestibular Schwannoma
Primary: Change in Visual Acuity During Head Movement From Baseline to Discharge — 0.198; .296 LogMAR
N/A N=18 Production of a Device to Obtain Continuous Ambulatory Vestibular Assessment (CAVA) - Healthy Volunteer Trial
Optokinetic Nystagmus
Primary: Sensitivity and Specificity of a Computer Algorithm to Detect Artificially Induced Nystagmus — 99.1; 98.6 Percent
N/A N=44 Novel Portable Diagnostic Device for Automatic Detection of Relative Afferent Pupillary Defect
Multiple Sclerosis · Glaucoma
Primary: Number of Participants With Detected Relative Afferent Pupillary Defect (RAPD) — 44; 37 participants
Phase 2 N=130 Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
Vertigo · Dizziness
Primary: VRT vs. ED SOC Six-Category Diagnosis Accuracy (Primary Analysis-eligible Participants, Two-arm Comparison) — 24; 18; 33; 38 Participants
N/A N=6 Vestibular Rehabilitation and Otolith Dysfunction
Dizziness
Primary: Change in Static Subjective Visual Vertical (SVV) — 0.69; 0.58; 0.69; 0.89 degrees — p=0.97
N/A N=26 Eye Movement Recordings in the Diagnosis of Traumatic Brain Injury
Traumatic Brain Injury
Primary: Stability of Fixation — 0.8; 1.1 degrees
Phase 2 N=14 Non-intrusive Detection of Temporary Neurologic Impairment By Opioids
Healthy
Primary: Oculo-Cognitive Addition Test (OCAT) Completion Time — 57.22; 57.22; 59.56; 58.18 seconds
Phase 2 N=19 Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis
Multiple Sclerosis · Internuclear Ophthalmoplegia · Fatigue
Primary: Pulse Size Ratio (PSR): Abducting/Adducting Eye Ratio for Saccadic Peak Velocity. — 1.914; 1.937; 1.805; 1.898 ratio — p=0.842672
N/A N=24 Computerized Vestibular Rehabilitation
Vestibular Diseases
Primary: Vestibulo-ocular Reflex Gain Ratio — 1.15 unitless gain ratio — p=<0.001
N/A N=40 Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
Astigmatism
Primary: Visual Acuity After Infero-temporal Version Movement. — 0.12; 0.1; 0.16; 0.14 LogMAR units — p=0.02
N/A N=5 Otolith Function in Patients With Primary Ciliary Dyskinesia
Primary Ciliary Dyskinesia
Primary: Vestibular Evoked Myogenic Potentials (VEMPs) — 0; 3; 2 participants
N/A N=100 Visual Function During Gait in Parkinson's Disease: Impact of Cognition and Response to Visual Cues
Parkinson's Disease
Primary: Visual Sampling Parameter: Saccade Frequency During Gait — 0.48; 0.76; 0.67; 0.77 Saccade frequency (sacc/sec)
N/A N=100 Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion
Elevated Intracranial Pressure (ICP)
Primary: Changes in ONSD in mm With Changes in ICP in Healthy Volunteers. — 4.2 mm
Phase 2 N=107 Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy
Acute Unilateral Vestibulopathy (AUV)
Primary: Standing Vertigo Intensity — 165.10; 155.10; 136.60 mm*day — p=0.8466
Phase 2 N=22 Safety and Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION).
Non-arteritic Ischemic Optic Neuropathy · Optic Nerve Injuries
Primary: Mean Increase From Baseline in ETDRS Letters Read at 26 Weeks and Off-drug Follow-up Visit — 15; 7; 9; 6 EDTRS Letters
Phase 4 N=37 Study to Evaluate OXERVATE® in Patients With Stage 1 Neurotrophic Keratitis
Neurotrophic Keratitis
Primary: Corneal Epithelial Healing — 5; 28 Participants
Phase 4 N=119 Clinical Investigation of the Vision-R800 Device.
Myopia · Hyperopia · Astigmatism
Primary: Subjective Questionnaire Response — 22; 32; 5; 3 Participants
N/A N=46 Vestibular Stimulation in Parkinson's Disease
Parkinson's Disease
Primary: Change From Baseline in the Nonmotor Symptom Severity Scale (NMSS) — -33.5; -2.0 change in scale total score — p=0.0089
N/A N=30 Virtual Environments for Vestibular Rehabilitation
Dizziness Chronic · Vertigo, Peripheral · Fall
Primary: Visual Vertigo Analog Scale (VVAS) — 43.05; 36.84; 31.28; 21.41 score on a scale — p=0.027
N/A N=40 Citicoline in Non-Arteritic Ischemic Optic Neuropathy
Non-arteritic Ischemic Optic Neuropathy
Primary: Change From Baseline in Visual Acuity at 9 Month — -0.0574; 0.0535 LogMAR
N/A N=14 Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
Astigmatism
Primary: Lens Orientation During Head Tilt. — 12.2; 39.7; 27.6; 39.3 Degree of rotation — p=<0.0001
N/A N=217 A Prospective Observational Study of Adult Strabismus
Convergence Insufficiency · Divergence Insufficiency · Hypertropia
Primary: Number of Participants With Symptom Success at 10 Weeks — 25; 91; 12 Participants
N/A N=65 The Effect of Sedation on Eye Movements
Saccadic Eye Movements
Primary: Dynamic Eye Movement Measures — -25; -115; -90; 10 (degrees/second)
N/A N=26 Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients
Benign Paroxysmal Positional Vertigo
Primary: Likert Scale for Satisfaction — 9; 9 units on a scale
N/A N=136 How Accurately Does the Diopsys Visual Evoked Potential (VEP) Vision Testing System Detect Glaucoma?
Glaucoma Diagnosis
Primary: Visual Evoked Potential (VEP) — 6.7; 7.1; 4.1 microvolts (uV) (amplitude)
Phase 2 N=113 Phase 2 Clinical Trial to Evaluate OC-01 Nasal Spray in Subjects With Neurotrophic Keratopathy
Neurotrophic Keratopathy
Primary: Mean Change From Baseline in Corneal Fluorescein Staining — -0.6; -0.9 score on a scale
N/A N=155 Eye Movements, Visual Perception and Attention
Vision
Primary: Average Performance in Visual Tasks — 74 percentage