Clinical Trial Search

Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline

Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale

Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants

Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants

Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 48.4; 48.4; 43.5; 41.2 units on a scale — p=0.158

Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms

Primary: Sum of Change in Brief Arthritis Stiffness Scale (BASS) Scores Over the 4-day Treatment Period — -12.6; -13.6; -11.7; -2.3 Scores on a scale

Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg

Primary: Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument — 3.3; -1.0; 3.1; 0.8 units on a scale

Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141

Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants

Primary: Change at 6 Months From Baseline in First Peak Knee Adduction Moment (KAM): (6 Month Value - Baseline) — -0.19 %Bw*Ht

Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003

Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025

Primary: The Percentage of Participants Achieving ≥30% Decrease From Baseline in Pain Intensity as Measured by WOMAC (Western Ontario and McMaster Universities Osteoarthritis…

Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants

Primary: Change From Baseline to Last 5 Days of Treatment in the Average Evening Pain Intensity In the Target Knee When Walking on a Flat Surface Using a Mixed Model for Repeated…

Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — 43.3; 34.1 units on a scale

Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495

Primary: Pain Scores Measured by Western Ontario and McMaster Universities Index (WOMAC) Survey — 3.98; 5.54 units on a scale

Primary: Treatment Adherence — 24; 18 Participants

Primary: Australian Canadian OA Hand Index (AUSCAN) — 3.3; 1.3; 2.0; 1.6 score on a scale

Primary: Change in 6-minute Walk Test — 22; 49 meters

Primary: Change in Synovitis — 9.8 units on a scale

Primary: Number of Adverse Events — 22 Adverse Events (AEs)

Primary: Change in WOMAC Pain (0-20 Scale) — -0.14; -0.65 units on a scale

Primary: Change From Baseline to Month 4 for Minutes of Moderate to Vigorous Intensity PA Per Week — 0.78 minutes — p=0.5145

Primary: Measure: Pain On Movement (POM) — 42.9; 42.1 units on a scale

Primary: Medial Condylar Separation With Brace — 0.60 mm

Primary: Pain — 6.01; 5.77; 5.92; 5.84 units on a scale — p=0.007