N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
N/A N=19 Feasibility of Pain Informed Movement for Knee OA
Knee Osteoarthritis
Primary: Acceptability of Content — 13 Participants
N/A N=71 Molecular Pathways Involved in Knee Pain
Knee Osteoarthritis · Knee Pain Chronic
Primary: Pain Sensitivity: Pressure Pain Detection Threshold (PPT) — 252.58; 266.17 kPa
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=110 Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee
Chronic Diseases · Obesity · Osteoarthritis
Primary: WOMAC Function — -10.4; -4.8; -4.9; -1.6 Change in Score — p=0.0129
Phase 2 N=260 Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants
Phase 2 N=147 A Study in the Treatment of Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Primary: Change From Baseline in Weekly Mean 24-hour Average Pain Severity (APS) Score From Electronic Diary at 5 Weeks — -2.05; -2.10; -2.09 units on a scale
N/A N=20 Geniculate Artery Embolization for the Treatment of Knee Pain
Osteoarthritis Of Knee
Primary: Patient Function (Units on a Scale) — 31 units on a scale
Phase 3 N=697 Tanezumab in Osteoarthritis of the Knee
Arthritis · Osteoarthritis
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale at Week 16: Baseline Observation Carried Forward (BOCF)…
Phase 3 N=231 Duloxetine Versus Placebo for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Primary: Weekly Change From Baseline in the 24-Hour Average Pain Rating Using an 11-Point Numerical Likert Scale Patient Diary — -0.36; -0.84; -0.95; -1.54 units on a scale…
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
Phase 4 N=120 Osteoarthritis Knee Pain Relief Study of 0.25% 920-CGS-200
Osteoarthritis, Knee
Primary: Percentage of Subjects With 50% or Greater Pain Score Reduction From Baseline to 24 Hours After First Dose of Study Drug Treatment. — 27.03; 20.0; 23.08; 20.0 percentage…
Phase 2 N=58 Maximizing Analgesia to Reduce Pain in Knee Osteoarthritis
Knee Osteoarthritis
Primary: Largest Change From Baseline on Clinical Pain Rating — 24.19; 30.48; 28.55; 26.38 score on a scale — p=.021
N/A N=79 Gait Modification Treatment for Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495
Phase 3 N=256 Duloxetine vs. Placebo in the Treatment of Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Primary: Change in Brief Pain Inventory (BPI) 24-hour Average Rating — -1.80; -1.12; -2.47; -1.41 units on a scale — p=<0.001
N/A N=45 Yoga as an Intervention for Women With Knee Osteoarthritis
Osteoarthritis
Primary: Change in Knee Extensor Torque — 130.1 Nm
Phase 2 N=291 A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee
Osteo Arthritis Knee
Primary: Daily "Average Pain Over the Last 24 Hours" Score at Week 4 — 5.9; 5.9; 6.1; 5.9 score on a scale
Phase 2 N=169 Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee
Osteoarthritis of the Knee
Primary: Time-to-Exit From Current Study Treatment — 31; 20; NA; NA Days — p=0.1006
N/A N=90 Resistance Exercise and Knee Osteoarthritis Pain, Functional Impairment and Cartilage Turnover
Knee Osteoarthritis
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC Score); Change From Baseline at 4 Months — 27.1; 33.3; 28.9; 26.7 units on a scale
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
N/A N=64 Needling Techniques for Knee Osteoarthritis
Knee Osteoarthritis · Kidney Yin Deficiency · Kidney Yang Deficiency
Primary: WOMAC Total in Week 15 — 11.6; 54.4 score on a scale — p=<0.001
N/A N=345 STepped Exercise Program for Knee OsteoArthritis
Osteoarthritis, Knee
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003
Phase 2 N=286 Efficacy and Safety of XT-150 in Osteoarthritis of the Knee
Osteoarthritis, Knee
Primary: Stage A: Number of Participants Achieving 30% Improvement From Baseline in Western Ontario and McMasters Arthritis Index (WOMAC) Pain Score — 26; 28; 38; 53 Participants
Phase 1 N=33 Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)
Osteoarthritis, Knee
Primary: Change in Average Pain Intensities Measured From the Pre-Treatment Walk (Baseline) at 3 Post-Treatment Walks — 0.24; 0.18; 0.18 Units on a Scale — p=0.743
N/A N=180 Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain
Knee Osteoarthritis
Primary: Absolute Change From Baseline in Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain Subscale Score at Day 30 — -16.33; -8.79 score on a scale…
N/A N=320 Group Physical Therapy for Knee Osteoarthritis
Osteoarthritis
Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 43.7; 43.7; 36.5; 39.1 units on a scale — p=0.1024
N/A N=69 Pain Informed Movement for People With Knee Osteoarthritis
Knee Osteoarthritis
Primary: Percentage of Follow up — 28; 31 Participants
Phase 2 N=40 Efficacy and Safety of Synera in Osteoarthritis Pain
Knee Osteoarthritis
Primary: Index Knee Pain Scores on a Numeric Rating Scale (NRS) — 4.167; 4.703 units on a scale
N/A N=93 Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
Knee Osteoarthritis
Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale