N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=7 Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Anterior Cruciate Ligament Injuries · Exercise · Cartilage, Articular
Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
N/A N=300 Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
Osteoarthritis
Primary: Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) — 48.4; 48.4; 43.5; 41.2 units on a scale — p=0.158
N/A N=41 Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Hip Osteoarthritis
Primary: Change in 6-minute Walk Test — 22; 49 meters
Phase 2 N=260 Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants
N/A N=60 Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)
Osteoarthritis
Primary: Change From Baseline to Month 4 for Minutes of Moderate to Vigorous Intensity PA Per Week — 0.78 minutes — p=0.5145
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
N/A N=240 Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
Osteoarthritis
Primary: Change From Baseline to Month 6 in Objectively Assessed Physical Activity (Accelerometer) — -2.40; -10.8 Minutes per week — p=0.3086
Phase 2 N=41 A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
Osteoarthritis, Knee
Primary: Sum of Change in Brief Arthritis Stiffness Scale (BASS) Scores Over the 4-day Treatment Period — -12.6; -13.6; -11.7; -2.3 Scores on a scale
Phase 2 N=389 A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
Osteoarthritis of the Knee
Primary: Change From Baseline to Last 5 Days of Treatment in the Average Evening Pain Intensity In the Target Knee When Walking on a Flat Surface Using a Mixed Model for Repeated…
N/A N=58 Mobility Optimization Through Velocity Exercise
Knee Osteoarthritis
Primary: Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument — 3.3; -1.0; 3.1; 0.8 units on a scale
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
N/A N=24 Group Physical Therapy for Knee Osteoarthritis
Osteoarthritis
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — 43.3; 34.1 units on a scale
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
N/A N=101 Role of Bone in Knee Osteoarthritis (OA)
Osteoarthritis, Knee
Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants
N/A N=79 Gait Modification Treatment for Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495
N/A N=345 STepped Exercise Program for Knee OsteoArthritis
Osteoarthritis, Knee
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003
Phase 1 N=8 Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
Knee Osteoarthritis
Primary: Safety and Tolerability of Single IA Administration of 4P-004 at Escalating Doses in Participants With Knee OA. — 5; 5; 5; 6 participants
Phase 2 N=395 Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in Minimum Joint Space Width in the Medial Compartment of the Tibiofemoral Joint of the Signal Knee After 1 Year of Treatment — -0.1361; -0.0442; -0.2261; -0.2000…
N/A N=25 A Biomarker Stress Test for Detection of Early Osteoarthritis
Osteoarthritis
Primary: Change at 6 Months From Baseline in First Peak Knee Adduction Moment (KAM): (6 Month Value - Baseline) — -0.19 %Bw*Ht
N/A N=10 Falls Prevention Program for Adults With Osteoarthritis
Osteoarthritis · Falls, Accidental
Primary: Participant Adherence to Intervention — 5 Participants
N/A N=351 Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
Osteoarthritis
Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26
N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared