Phase 4 N=52 Regional Anesthesia Following Pediatric Cardiac Surgery
Atrial Septal Defect · Ventricular Septal Defect · Pain, Procedural
Primary: Total Amount of Opioid Medications Administered — 0.44; 0.83 MME/kg — p=0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=2,108 Regional Anesthesia and Breast Cancer Recurrence
Breast Neoplasms
Primary: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery — 111; 102 participants — p=0.84
N/A N=120 General or Regional Anesthesia for Hip Surgery
Osteoarthritis
Primary: Length of Hospital Stay — 30; 26 hours
N/A N=80 Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia
Hip Fractures
Primary: Success Rate (Supplemental Medication) — 22; 20; 3 Participants
N/A N=386 Regional Anesthesia Military Battlefield Pain Outcomes Study
Anxiety Disorders · Complex Regional Pain Syndrome Type II · Depressive Disorders
Primary: Neuropathic Pain Scale - Pain Intensity — 3; 3.44; 3.92; 3.04 units on the Neuropathic Pain Scale — p=<0.0001
Phase 4 N=166 Local Anesthesia Versus Saline Serum in Surgical Incision of Colorectal or Hepatic Surgery
Postoperative Pain · Surgery · Postoperative Complications
Primary: Mg of Morphine Consumption During 48 Hours Administered by Patient Controlled Analgesia System — 23; 52; 24.63; 26.78 mg
Phase 4 N=159 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Osteoarthritis, Hip
Primary: Percentage Ambulating Early After Spinal Anesthesia — 9; 20; 35 Participants
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
Phase 4 N=46 Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Pain Management
Primary: Participant Pain Control — 4.5; 5.87; 4.63; 5.00 units on a scale — p=0.16
N/A N=60 Epidural Anesthesia for Transurethral Resection of The Prostate
Epidural Catheter · Epidural Analgesia · Geriatric Cardiology
Primary: Time to Reach Sensory Block at T10 — 15.25; 10.50; 11.25 Minutes — p=0.05
N/A N=154 Effect of Local Anesthetic Dose on Interscalene Block
Shoulder Arthroscopy · Interscalene Block
Primary: Handgrip Strength — 6.45; 2.98 kg
Phase 4 N=36 Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
Nerve Block · General Anesthesia · Spinal Anesthesia
Primary: Time Until Patient is Ready for Discharge From Post-Anesthesia Care Unit (PACU) to Home. — 81; 43.5 Minutes
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
Phase 4 N=14 Anesthesia for Pain After Ankle Fracture Surgery
Chronic Pain · Ankle Fracture Surgery · Regional Anesthesia
Primary: Pain Score at 12 Months - Experimental Group vs. Control Group — 36.33; 44.00 units on a scale — p=0.1269
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
Phase 4 N=100 Regional Block for Postoperative Free Flap Care
Pain Management
Primary: Opioid Utilization Measured in Oral Morphine Equivalent (OME) — 118; 166 mg
Phase 4 N=24 Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks
Relatively Healthy Volunteers
Primary: Maximum Tolerance to Transcutaneous Electrical Stimulation — 27.0; 26.9 mA (milliamperes) — p=0.02
Phase 4 N=50 Optimizing Local Anesthetic Concentration for Continuous Lumbar Plexus Nerve Blocks
Hip Arthroplasty · Hip Pain
Primary: Percent Change From Baseline in Quadriceps Femoris Maximum Voluntary Isometric Contraction (MVIC) — 64.1; 68 percentage change from baseline of MVIC
Phase 4 N=165 Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty
Primary: Maximum Pain Post-Operative Day (POD) 1 (Morning) — 3; 4; 4.5 units on a scale — p=0.144
N/A N=70 Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses
Pain, Acute · Anesthesia, Local · Trauma Injury
Primary: Average Pain Queried on First Postoperative Day — 3; 0.0 score on a scale — p=0.033
N/A N=30 Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Brachial Plexus Blockade
Primary: Overall Duration of Sensory Block. — 165; 188 minutes — p=<0.001
N/A N=300 Evaluation of Factors Associated With Patient Satisfaction and Mood-State in Regional Anesthesia
Outcome Assessment · Patient Satisfaction
Primary: Overall Patient Satisfaction — 247; 53 Participants
Phase 4 N=43 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
Adverse Reaction to Spinal Anesthetic · Maternal Care for Cervical Incompetence
Primary: Time to Resolution of Motor Block — 109; 112 minutes
Phase 4 N=31 Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension
Tourniquet Hypertension · Intraoperative Hypertension · Total Ankle Arthroplasty
Primary: Number of Subjects Experiencing Tourniquet Hypertension — 5; 14 Participants
N/A N=950 Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery
Post Operative Delirium
Primary: Number of Participants With Post-operative Delirium in 7 Days Post Operation — 29; 24 Participants
Phase 4 N=183 Spinal Anesthesia With Hyperbaric Levobupivacaine 0.75% for Ambulatory Knee Arthroscopy
Disorder of Knee · Anesthesia
Primary: Probability of Motor Block — 5; 20; 27 percentage of motor block
N/A N=116 Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Spine Surgery
Primary: Mean Pain Scores — 4.4; 5.3 verbal response scores — p=<0.001
N/A N=23 Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Infants Undergoing Surgery
Primary: Cerebral Non-invasive Near Infrared Spectroscopy (NIRS) — 0.05 percentage change per minute
Phase 4 N=24 Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Application Site Discomfort · Medical Device Discomfort
Primary: Time in Minutes That Tq Remained Inflated — 30.5; 22.4 Minutes
N/A N=36 Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
Thyroid Neoplasms · Goiter, Nodular · Thyroid Nodule
Primary: Intraoperative Fentanyl Administration — 187.5; 185.7; 144.2; 156.3 mcg