Clinical Trial Search

Primary: Percent of Patients With Success as Defined by no or Mild Pain as Analyzed on a VAS Scale and no Narcotic Use — 52; 43 percentage of participants

Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)

Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale

Primary: Pain Intensity Measure: Visual Analogue Pain Scale — 11.8; 8.8; 9.4; 10.3 score on a scale — p=0.329

Primary: Changes Between Initial and Post Treatment Dimensions of Periapical Lesions — 37.34; 34.04; 16.20; 17.54 square millimeters — p=<0.01

Primary: Number of Participants With a PAI Score of < 3, = 3, or = 4 or 5 — 51; 3; 0 Participants

Primary: Number of Colony Forming Units Per Millilitre — 80300000; 79900000; 74000000; 73000000 CFU/ml

Primary: Comparison of MTA/FS Pulpotomy Versus RCT Treated Incisors With Acceptable Radiographic Outcome at 12 Months Post-procedure. — .97; .92 Proportion of incisors — p=.15

Primary: Metabolic Activity of Persistent Bacteria — 4.748; 2.57; 2.614; 4.0008 RNA/DNA ratio

Primary: Clinical Postoperative Pain — 30.5; 20.6 score on a scale

Primary: Clinical Success at 6 Months — 27; 30 Participants

Primary: State-Trait Anxiety Inventory State Sub-scale (STAI-S) Score at the End of the Appointment — 27.39; 29.37 units on a scale — p=.399

Primary: Change From Baseline in Root Canal Bleeding Score — 2.33; 0.13 score on a scale — p=<.0001

Primary: Post-operative Diameter of the Periapical Lesion — 2.07; 0.98; 1.12; 0.78 Post-operative lesion diameter- mm2

Primary: Clinical Examination — 30; 30 Participants

Primary: Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) — 16; 37; 29; 26 Participants

Primary: Effect of Trypsin-Chymotrypsin on Post-operative Pain After Single Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis — 3.47; 3.53; 2.93; 6.13 score on…

Primary: 24 Hour Postoperative Pain for Patients Seen From 09/2020-06/2021 — 14.75; 16.23 score on a scale — p=0.63

Primary: Failure Rate of the Three Treatment Arms Judged Clinically — 37; 31; 39; 2 Teeth — p=0.02

Primary: The Primary Outcome Parameter Will be the Difference in Bacterial Reduction Between the Experimental and Control Disinfection Groups Group (Ferumoxytol) and Comparison…

Primary: Root Caries Activity — 3.72; 40.52 Percentage of active lesions (2-years)

Primary: Survival of Capped Pulps — 842; 1201 Survival days — p=<0.01

Primary: Success Rate Based on Pulp Vitality Tests (Vital/Non Vital) — 96.2; 100; 100; 86 Percentage of success rate — p=>0.1

Primary: Post-operative Pain on the Visual Anlogue Scale (VAS) at the 6-hour Post-operative Interval — 5; 3.2; 3.5 units on a scale

Primary: Number of New Tooth Root Caries Lesions — 1.1; 0.43; 0.56 new carious root surfaces

Primary: Bacterial Count of Streptococus Mutans — 2.00; 2.04; 1.12; 1.05 CFU/ml log10

Primary: Post Operative Pain — 3.18; 2.27; 2.20; 1.39 score on a scale — p=0.083

Primary: Number of Participants With Treatment Failure — 2; 2 participants

Primary: Number of Participats Showing Efficacy (Functionality) — 18; 18 Participants

Primary: Change From Baseline in Root Canal Bleeding — 3.40; 3.73; 0.26; 3.03 millimeters — p=<.0001