N/A N=21 Virtual Neuroprosthesis: Restoring a Sense of Touch to Amputees
Amputation
Primary: Artificial Hand Grasp Performance Metrics — 90.6 percentage of successful transportation
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=12 Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap
Sensory Reconstruction of the Volar Aspect of the Finger · The Heterodigital Neurocutaneous Island Flap
Primary: Discriminatory Sensation of the Flap — 8.3 mm
N/A N=9 Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
Infection Wound · Disruption of Nerve Repair
Primary: 2-point Discrimination Test — 7.5 mm
N/A N=45 Novel Training Environment to Normalize Altered Finger Force Direction Post Stroke
Stroke
Primary: Action Research Arm Test (ARAT) — 3.5; 0.8 score on a scale
N/A N=12 Sensory Stimulation to Enhance Hand Function Post Stroke
Stroke
Primary: Box and Block Test (BBT) About a Week After the 2-week Intervention — 6; -2 change in # of blocks
N/A N=12 Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke
Stroke · Physical Disability
Primary: Short-latency Afferent Inhibition — 48; 21 % of unconditioned motor evoked potentia
N/A N=9 Treatment of Painful Digital Neuroma Using A Pedicled Nerve Flap
Painful Digital Neuroma
Primary: Static 2-point Discrimination Test — 7.3 mm
N/A N=87 Frontal and Parietal Contributions to Proprioception and Motor Skill Learning
Basic Science
Primary: Motor Skill — 66.6; 59.4; 59.9; 64.9 Accuracy (%) — p=0.55
N/A N=18 Validation Study Of A Digital Measuring Device For Central Hand Representation In Children With A Neonatal Brachial Plexus Palsy
Neonatal Brachial Plexus Palsy
Primary: Intrarater Reliability of Implicit Finger Length Estimates Using the HandUZ Device — 0.91; 0.92 Intraclass Correlation Coefficient
N/A N=4 Dexterous Partial Hand Prosthesis Outcomes
Amputation · Amputation; Traumatic, Hand · Limb; Absence, Congenital, Upper
Primary: Jebsen-Taylor Small Common Objects Functional Test — 34.8; 26.1; 97.2; 62.1 Seconds
N/A N=76 Neural Basis of Sensory and Motor Learning: Functional Connections
Basic Science
Primary: Resting-state PMv-M1 Functional Connectivity (Fisher Z-transformed Correlation) — 0.64 unitless (Fisher z-score)
N/A N=61 Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
Stroke · Physical Disability
Primary: Change in Wolf Motor Function Test (WMFT) Movement Time — -4; -9 Seconds (sec)
N/A N=1 Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
Spinal Cord Injuries · Tetraplegia · Quadriplegia
Primary: Ability to Form Appropriate Grasp Patterns — 78.75 percentage of correct grasps formed
N/A N=5 Neural Adaptation After Tendon Transfer and Training in Tetraplegia
Spinal Cord Injury
Primary: Pinch Force — 8.7; 10.6 newtons
N/A N=4 Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Phantom Limb
Primary: Stimulation Thresholds to a Variety of Stimulus Parameters — 2.13 milliamps
N/A N=13 Sensory Stimulation During CIMT
Cerebral Palsy
Primary: Feasibility (Total Number of Hours That Participants Wear the Device) — 28.3; 27.9 Hours
N/A N=31 Thumb Osteoarthritis: A Cross-Sectional Study of Mechanisms
Carpometacarpal Osteoarthritis
Primary: Australian Canadian OA Hand Index (AUSCAN) — 3.3; 1.3; 2.0; 1.6 score on a scale
N/A N=8 Sensorimotor Imaging for Brain-Computer Interfaces
Functional Neuroimaging
Primary: Peak Activity Volume: Right D1 Attempt Movement Activity at S1 - SCI — 893.6 mm^3
N/A N=13 Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI
Spinal Cord Injuries · Hand Weakness
Primary: Percent Change in Time to Achieve Secure Grasp (Cognition Glove Only) — 39.9; -14.6; 10.1 % change in time to secure grasp
Early Phase 1 N=44 Sensory Augmentation Methods in Stroke
Stroke
Primary: Percentage of Participants With Related or Serious Adverse Events — 1; 0 Participants — p=1
Phase 2 N=12 Extension of the MIME Robotic System for Stroke Rehabilitation
Stroke · Impaired Upper Extremity Function
Primary: Fugl-Meyer Test of Motor Function — 1.9; .8; 1.3; .8 units on a scale
N/A N=81 Thumb vs Great Toe Recovery
Residual Neuromuscular Blockade
Primary: Onset Time of Muscle Relaxation for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles — 180.0; 180.0 seconds
N/A N=5 Functional Connectivity & Stimulation-enhanced Therapy Post Stroke
Stroke
Primary: Mean Change in Hand Motor Function — 0.83 blocks
N/A N=13 Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury
Spinal Cord Injury · Tetraplegia · Paresis
Primary: Grasp Release Test — 58.5; 72.0; 77.5 Objects moved — p=<0.025
N/A N=14 Passive Tactile Stimulation for Stroke Rehabilitation
Stroke · Stroke, Ischemic · Stroke Hemorrhagic
Primary: Change in Modified Ashworth at 12 Weeks — 1.1 units on a scale — p=0.00025
N/A N=5 Validation of Point Partial User Needs With Partial Finger Amputees
Amputation; Traumatic, Hand
Primary: VAL-1: System Comfort Validation Test — 100 % of participants who Passed test
N/A N=3 Development of a FES Device for Hand Use During Arm Activities Following Stroke
Stroke · Hand Function
Primary: Box and Blocks Test (BBT) Score Across the 12 Weeks of the Intervention, Immediately After Conclusion of Intervention, and 3 Months Post-intervention — 13.74; 21; 19.67…
N/A N=30 Effects Of Sensory Training and Electrical Stimulation on Sole of The Foot Sensations in Patients With Acute Hemiplegia
Hemiplegia · Stroke, Acute · Sensory Disorders
Primary: Assessment Of Joint Position Sense — 5.0; 6.4; 8.1; 8.6 correct responses
N/A N=11 Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury
Spinal Cord Injury
Primary: Conduct pre-and Post-training Assessments of Behavioral Outcomes Using Wolf Motor Function Test and Jebsen Taylor Hand Function Test to Measure Upper Extremity Function…
N/A N=5 Multisensory Rehabilitation of Hemianopia
Hemianopia
Primary: Number of Points Detected at Multiple Locations — 14.0; 94.9; 63.6; 95.4 Number of points